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41.
Rym Afiouni Josiane Helou Stephanie Matar Roland Tomb 《The Journal of clinical and aesthetic dermatology》2021,14(2):22
Rosacea and cutaneous lupus erythematosus (CLE) are chronic inflammatory dermatoses. To our knowledge, no cases of granulomatous rosacea (GR) associated with CLE have been previously reported in the literature. We describe the case of a 38-year-old female patient who presented to our clinic with a diffuse scaly facial erythema, with the codiagnoses of GR and CLE later confirmed with clinicopathological correlation. 相似文献
42.
43.
外伤后细菌性致死性肉芽肿的透射电镜观察 总被引:8,自引:0,他引:8
目的:外伤后细菌性致死性肉芽肿是一种尚未被认识的新疾病,近20a来在我国多个地区已发现20余例,无一存活。本研究 应用透射电镜寻找病原体,为该病的诊断和治疗提供线索。方法:以透射电镜观察2例外伤后细菌性致死性肉芽肿的活检组织,寻找该病的病原。结果:病变组织内主要为组织细胞、多核巨细胞,细胞内有大量溶酶体样结构,部分溶酶体样结构具有“杆菌”形态,另见少数球菌。根据电镜下的发现成功分离出1种严格的厌氧性细菌,初步确定为放线菌,并根据细菌药敏结果救活了1例患。结论:对于怀疑由病原体所致的疾患,电镜下发现损害中的病原体是最具说服力的证据,本病的发现和命名,电镜发挥了关键作用。 相似文献
44.
45.
双氯酚酸钠米索前列醇片的抗炎作用研究 总被引:3,自引:0,他引:3
双氯酚酸钠米索前列醇片(DSMT)(20,10mg/kg)连续2d灌胃给药可显著地抑制二甲苯所致鼠耳肿胀(P〈0.01,P〈0.05);DSMT(15,7.5mg/kg)灌胃给药均可非常显著抑制角叉菜胶至炎后3h内大鼠足肿胀;DSMT高、低剂量组(15,7.5mg/kg)灌胃给药7ddisplay structure 相似文献
46.
Inflammatory pseudotumors have been recognized in many parts of the body. A case of a diffuse variant which involved the testis,
the epididymis and the spermatic cord is described. The patient had enlarged left testis for several months. Clinically, the
lesion mimicred cancer. Histologically, the lesion contained hyalinized fibrous tissue with spindle cells, plasma cells and
lymphocytes. Gradual involvement of vascular channels by the cellular elements of inflammatory pseudotumor was observed. Results
of immunohistochemical studies showed a myofibroblast differentiation in the majority of spindle cells: intense antibody staining
for smooth muscle actin, muscle specific actin, and vimentin. The ultrastructural findings, intracytoplasmic filaments with
dense bodies, were also consistent with the myofibroblastic nature of these cells. The histiocyte differentiation of spindle
cells is questionable in our case, because only scattered histiocyte-like cells showed positivity with the KP-1 (CD-3) antibody. 相似文献
47.
Inflammation markers in nasal lavage, and nasal symptoms in relation to relocation to a newly painted building: a longitudinal study 总被引:1,自引:0,他引:1
Wieslander G Norbäck D Wålinder R Erwall C Venge P 《International archives of occupational and environmental health》1999,72(8):507-515
Introduction: There is a need to evaluate possible health effects of ventilation improvements and emissions from new buildings, in longitudinal
studies. New methods to study biological effects on the eyes and upper airways are now available. Material and methods: A longitudinal study was performed on 83 trained social workers in two offices in Uppsala, Sweden. The exposed group (n= 57) moved to a newly redecorated building nearby. Low emitting building material had been used, including a new type of
solvent-free water-based paint. The control group (n= 26) worked in the same office during the study period (November 1995 to February 1996). Hygiene management was carried out
in both offices, at the beginning and the end of the investigation. Tear film stability (BUT) was measured. Nasal patency
was measured by acoustic rhinometry, and eosinophilic cationic protein (ECP), myeloperoxidase (MPO), lysozyme and albumin
were analyzed in nasal lavage fluid (NAL). Results: The relocation resulted in an increase in the personal outdoor airflow rate from 11 to 22 l/s. Indoor concentrations of terpenes
were higher in the new building, and powdering of the new linoleum floor was observed. Measurements showed low levels of volatile
organic compounds (VOC), formaldehyde, carbon dioxide (CO2), nitrogen dioxide, respirable dust, and microorganisms in the air of all buildings. The move resulted in an increased nasal
patency and an increase of ECP and lysozyme in NAL, after adjusting for changes in the control group. No changes were observed
for nasal or ocular symptoms. A seasonal effect, with a decrease of ECP, was observed in the control group. Conclusion: A well-ventilated office building can be redecorated without any major ocular or nasal effects, or measurable increase of
indoor air pollution if low-emitting building materials are selected. In agreement with previous evidence, the improved ventilation
flow may explain the increase of nasal patency. The increase of ECP and lysozyme in NAL suggested an inflammatory effect in
the new building. Since this building had increased ventilation flow, increased concentrations of terpenes, and powdering
from the polish on the new linoleum floor, identification of causative agents was difficult. The hygiene measures did not
give any evidence that emissions from the new type of solvent-free water-based paints or building dampness were responsible
for the observed nasal effects. Considering the higher emissions of VOC reported from older types of water-based latex paints
and solvent-based wall paints, the new type of solvent-free water-based paint seems to be a good choice from the hygiene point
of view.
Received: 21 December 1998 / Accepted: 20 June 1999 相似文献
48.
49.
H. Wiethölter J. Dichgans 《European archives of psychiatry and clinical neuroscience》1982,231(3):283-287
Summary In a case of Whipple's disease the diagnosis was made by careful cytologic evaluation of the cerebrospinal fluid (CSF), identifying Sieracki cells. A basal granuloma invaded the hypothalamus, diencephalon, and rostral parts of the brainstem. An exploration in the initial stage led to misdiagnosis as a granular cell tumor. Diagnosis was then confirmed by intestinal biopsy.
Zusammenfassung Es wird über einen Fall mit Morbus Whipple berichtet, der bei sorgfältiger Untersuchung des Liquor cerebrospinalis durch den Nachweis von Sieracki-Zellen diagnostiziert wurde. Die Exploration eines basalen Granuloms, das in den Hypothalamus, das Diencephalon und die rostralen Anteile des Hirnstamms eingewachsen war, hatte im Frühstadium zur Fehlinterpretation eines Granularzelltumors geführt. Die Diagnose wurde schließlich durch Dünndarmbiopsie bestätigt.相似文献
50.
目的研究嗜酸性细胞胃炎中的肥大细胞的分布及其意义。方法27例嗜酸性细胞胃炎常规切片.分别做pH6.40.5%甲苯胺蓝染色显示肥大细胞和2%硫染色人细胞异染颗粒,此镜观察。结果:在胃粘膜、粘膜下层及溃疡的肉芽组织中.均可见未释放型和释放型两种肥大细胞分布。不同部位不同类型的肥大细胞,被激活后均参与相应部位的炎性反应、引起粘膜溃疡和肉芽肿形成。结论本病的发生.主要与肥大细胞的分布和激活有着重要的关系。肥大细胞释放的各种介质、虽然双本病的发生起到重要作用,同时也具有一定的抗癌作用,这种病变属于一种迟发性免疫反应性疾病. 相似文献