Post-processing of DLP-printed denture base polymer: Impact of a protective coating on the surface characteristics,flexural properties,cytotoxicity, and microbial adhesion

ObjectivesTo investigate the effect of a protective coating on the surface characteristics, flexural properties, cytotoxicity, and microbial adhesion of vat-photopolymerization additive-manufacturing denture base polymers.MethodsThe specimens were additively manufactured using digital light processing (DLP). Specimen surfaces were coated with the same printed resin, and mechanical polishing was used for comparison. Surface topography, arithmetical mean height (S_a), and water contact angle values were measured. Furthermore, flexural strength (FS)/modulus and fractography were evaluated. Also, cytotoxicity was evaluated by an extract test. Finally, an adhesion test was used to investigate the adhesion of mixed oral bacteria to the specimens.ResultsThe S_a values in the polished (0.26 ± 0.08 µm) and coated (0.38 ± 0.14 µm) groups were significantly lower than in the untreated (2.21 ± 0.42 µm) and control (2.01 ± 0.37 µm) groups. The coating treatment resulted in a higher FS compared to the untreated surface (p = 0.0002). After the coating treatment, no significant differences were found in relative cell viability between the groups (p > 0.05). The quantitative results showed significantly higher bacterial adhesion in the untreated group than in the polished (p = 0.0047) and coated (p < 0.0001) groups.SignificanceThe surface characteristics and flexural properties were optimized by the protective coating. Also, the protective coating did not adversely affect cytocompatibility. Moreover, the coating treatment could effectively decrease oral bacteria adhering to the surfaces. Therefore, the protective coating treatment can be a less time-consuming alternative to mechanical polishing as a post-processing procedure for the digital denture.     

蒙药明目十一味丸对糖尿病视网膜病变Ⅰ期视网膜功能的影响

评价蒙药明目十一味丸治疗糖尿病视网膜病变（DR）Ⅰ期的临床疗效。方法：前瞻性临床研究。选取2016年7月至2017年3月在内蒙古民族大学附属医院眼科就诊的DRⅠ期患者120例（120眼），通过随机数字表法将其分成蒙药组和对照组各60例，蒙药组加用明目十一味丸，对照组加用羟苯磺酸钙胶囊，一个疗程28 d，共3个疗程。分别在治疗前后对2组患者进行多焦视网膜电图（mfERG）及超广角眼底照相检查，记录N1区域和P1区域的潜伏期、振幅变化及视网膜微动脉瘤和出血点的数目。采用t检验、χ2 检验对数据进行分析。结果：对照组和蒙药组在治疗前后mfERG测得的R1～R5 P1 区域的振幅密度值差异有统计学意义（t对照组=66.86、18.05、36.33、47.43、30.56，P<0.001； t蒙药组=31.52、54.56、101.98、127.02、45.74，P<0.001），N1区域的振幅密度值差异有统计学意义（t对照组=70.18、47.02、78.08、57.44、64.51，P<0.001；t蒙药组=46.09、140.47、145.14、50.46、73.94， P<0.001）。与对照组相比，蒙药组治疗前后R1～R5 P1、R1～R3 N1区域的振幅密度值差值差异有统计学意义（tP1=8.96、23.96、25.10、28.80、13.67，P<0.001；tN1=9.38、30.34、52.06，P<0.001）， R4～R5 N1区域的振幅密度值差值差异无统计学意义。2组治疗前后潜伏期比较，R1～R5 P1区域、N1区域的差异均无统计学意义。2组治疗前后微动脉瘤及出血点数目比较，差异有统计学意义（t=2.08，P=0.042；t=2.07，P=0.043）。眼底照相蒙药组与对照组有效率分别达88%、73%，差异有统计学意义（χ2 =4.36，P=0.037）。结论：蒙药明目十一味丸能明显改善Ⅰ期DR视网膜功能的损伤，疗效显著，可作为治疗DRⅠ期的常规用药。     

颅颌面整形手术机器人在颏部水平截骨手术中的精确性分析

目的 探讨颅颌面整形手术机器人在颏部水平截骨手术中的应用效果和精确性.方法 回顾分析2015年1月至2020年12月接受传统颏部水平截骨手术的10例小颏畸形患者(临床组)的临床资料,并通过颅颌面整形手术机器人对该组患者1:1的3D石膏模型(机器人组)进行颏部水平截骨手术操作.以本团队前期实验研究数据标准为参考,利用数字...     

闭合性指动脉损伤的诊断与治疗

目的探讨闭合性指动脉损伤采用血管移植修复的可行性。方法通过对2003年6月至2008年5月28例闭合性指动脉损伤病例采用血管移植修复受损的指动脉,总结闭合性指动脉损伤的诊断与治疗。结果本组28例手术后成活27例,成活率96．4％。平均随访12个月,采用国际手外科联合会Nako—mura tamal评价标准,优18例,良8例,中1例,失败1例,优良率为92．8％。结论确诊为闭合性指动脉损伤者,应积极治疗,尽早手术探查,采用血管移植修复损伤的指动脉。对损伤段血管的判断、术中血管移植,以及术后护理十分重要。     

The use of the Statscan digital X-ray unit in paediatric polytrauma

We present a 3-year review of clinical paediatric experience with the Statscan (Lodox Systems, Johannesburg, South Africa), a low-dose, digital, whole-body, slit-scanning X-ray machine. While focusing on the role of the unit in paediatric polytrauma, insight into its applications in other paediatric settings is provided.     

磁共振成像QA的自动实现方法

目的 提供一种磁共振成像质量保证(QA)日常检测的自动实现方法.方法 利用DICOM协议实现对QA参数计算的流程控制,由程序根据设定自动选择ROI区域并进行QA参数的计算和存储.结果 计算所得信噪比和漂移等QA参数能避免手动选择ROI等人为因素的影响,可较准确地反映设备状态.结论 此法简化了磁共振设备QA工作的操作流程,有利于历史数据的保存与回顾分析.     

甲亢性心脏病房颤患者的心肺X线表现分析

目的：分析与讨论甲状腺机能亢进性心脏病中房颤改变与X线表现意义。方法：按俞氏诊断标准排除其它疾病的40例甲心病,均在治疗前摄后前位（远达）X线胸片,其中合伴房颤36例（阵发性房颤16例,快速性房颤16例,房扑4例）。结果：X线线中肺淤血（肺静脉高压）,左房大与房颤关系明显,肺淤血程度和左房大与房颤改变联系紧密,对临床治疗有帮助。除此外甲心病XC线表现有高动力循环表现如肺血多,肺动脉段膨,右下肺动脉增粗,心脏改变如左室大、心衰等。结论：甲心病中房颤X线表现与病理改变关系密切,认识与注意相关X线表现对治疗有帮助,且意义较大。     

不同年龄组冠心病患者冠状动脉造影特点

目的:探讨不同年龄组冠心病(coronary heart disease,CHD)患者的临床及冠状动脉造影(CAG)特点。方法:将148例CHD患者,根据年龄分为中青年组(年龄<60岁,n=52)、普通老年组(年龄60~74岁,n=74)和高龄老年组(年龄>74岁,n=22),对三组患者一般资料、血生化指标及CAG结果进行分析,并经统计学处理。结果:中青年组高血压并发率低于高龄老年组(P<0.05)。中青年组以单支病变为主,而普通老年组和高龄老年组以多支病变较多(P<0.05),高龄老年组右冠状动脉病变高于中青年组(P<0.05),三组ACC/AHA积分差异无统计学意义(P>0.05),普通老年组和高龄老年组弥漫长病变多于中青年组(P<0.05)。结论:不同年龄组CHD有不同的临床和CAG特点,不同年龄人群应采取有针对性的CHD防治措施,对合理防治冠状动脉病变的发生和发展有重要意义。     

The Potential of Digital Microscopy in Breast Pathology

The rapidly evolving field of digital microscopy supports the efficient exploitation of inherent information from stained glass slides to offer widespread utilization in breast histopathology. Digital image signals can be accurately measured, integrated into databases and shared through computer networks. Therefore, digital microscopy can boost telepathology-consultation, gradual- and postgradual teaching, proficiency testing, intra- and interlaboratory validation of biomarker screening interpretation, and automated image analysis of biomarker expression for both diagnostics and research applications. This is a brief highlight of the potential of digital microscopy in breast pathology applications.     

CAD-CAM construction of an auricular template for craniofacial implant positioning: a novel approach to diagnosis

A novel approach to the diagnosis of bone available for craniofacial implant positioning is discussed in a case that required ear ablation for tumor removal. A mirrored volume of the healthy ear was rapidly prototyped for a clinical trial in an appropriate position relative to the patient's face. Three ideal positions for the implant were chosen in the inner of the volume of the mirrored ear. The same positions were transferred to a diagnostic template that was rapidly prototyped with a positioning arm extending to the zygomatic arch. Computed tomography (CT) revealed errors in the planning of the implant position and, as a clinical consequence, an implant site was excluded from surgical planning. A virtual elaboration for maxillofacial implant positioning was used to define the correct implant site in relation to the available bone, and two craniofacial implants were correctly positioned in the temporal bone.