1821例住院皮肤病例分析

本文报告了1821例住院皮肤病例分析结果:诊断正确率91.2％,总有效率97.8％,死亡率为0.5％。1821例中,最常见为皮炎湿疹、麻疹、荨麻疹、药疹、带状疤疹;此外还有银屑病,天疱疮,系统性红斑狼疮、皮肌炎……等。作者对诊断与治疗进行了简要分析并提出了进一步提高诊治水平的建议。     

PPARs与皮肤病的关系研究进展

过氧化物酶体增殖物激活受体（PPARs）在过氧化物酶体增殖、脂肪生成、B氧化增加和细胞周期的调节等方面起着重要作用，它在皮肤生理及病理方面的作用逐渐受到重视。PPARct影响皮肤的成熟、分化和增殖，皮肤外伤后，PPARβ／δ一直保持表达直到创口愈合。PPARs对皮脂形成、皮肤肿瘤发展有不同的影响，在银屑病和色素性皮肤病中也起一定的作用。这些发现可为治疗皮肤病提供新途径。     

“阳化气,阴成形”在皮肤科中的应用

"阳化气,阴成形"是中医学阴阳学说的重要组成部分,在皮肤病的发生发展及诊治过程中起着重要指导的作用。阳化气不足,阴成形太过,是皮肤病发生发展的重要原因之一;故温阳散邪、扶阳抑阴是皮肤病的重要治法。     

喀喇昆仑高原官兵皮肤病流行病学调查研究

目的：研究喀喇昆仑高原进驻者皮肤病流行病学特点。方法：由皮肤科医师按照统一调查方案对喀喇昆仑高原与兰州地区居住1年以上的某部官兵进行皮肤病普查,并对其可能的影响因素进行分析。结果：与兰州地区进驻者比较,喀喇昆仑高原进驻者部分皮肤病患病率显著增加。共发现36个病种,其中寻常痤疮、高原指甲凹陷症、高原性脱发、慢性唇炎和日光性皮炎是最常见的病种,共253例,占全部被调查对象的54.29%。结论：喀喇昆仑高原进驻者皮肤病谱有所不同,高原指甲凹陷症、高原性脱发和慢性唇炎的患病率显著增高。寻常痤疮、高原指甲凹陷症、高原性脱发、慢性唇炎和日光性皮炎是最常见的皮肤病。     

Dermatosis en pacientes con sobrepeso y obesidad y su relación con la insulina

IntroductionThe prevalence of obesity has increased worldwide in recent years. Some authors have described skin conditions associated with obesity, but there is little evidence on the association between insulin levels and such disorders.ObjectiveTo describe the skin disorders present in overweight and obese patients and analyze their association with insulin levels.Material and methodsThe study included nondiabetic male and female patients over 6 years of age who were seen at our hospital between January and April 2011. All the patients were evaluated by a dermatologist, who performed a physical examination, including anthropometry, and reviewed their medical history and medication record; fasting blood glucose and insulin were also measured. The patients were grouped according to degree of overweight or obesity and the data were compared using analysis of variance or the χ² test depending on the type of variable. The independence of the associations was assessed using regression analysis.ResultsIn total, 109 patients (95 adults and 13 children, 83.5% female) were studied. The mean (SD) age was 38 (14) years and the mean body mass index was 39.6 ± 8 kg/m². The skin conditions observed were acanthosis nigricans (AN) (in 97% of patients), skin tags (77%), keratosis pilaris (42%), and plantar hyperkeratosis (38%). Statistically significant associations were found between degree of obesity and AN (P = .003), skin tags (P = .001), and plantar hyperkeratosis. Number of skin tags, AN neck severity score, and AN distribution were significantly and independently associated with insulin levels.ConclusionsAN and skin tags should be considered clinical markers of hyperinsulinemia in nondiabetic, obese patients.     

渤海诸岛官兵皮肤病调查研究

目的调查渤海驻岛官兵皮肤病发病情况,了解诱发皮肤病的相关因素。方法采用普查法,在2011年和2015年分别对1 386名和1 000名驻岛官兵进行皮肤病流行病学调查。结果 2015年和2011年的皮肤病发病率无明显差异,2年中皮肤病高发病分布情况大致相同,但红斑鳞屑性、角化性皮肤病发病率排名有所提前。结论需进一步加强皮肤病防治措施,以减少非战斗性减员。     

血清C-反应蛋白测定对皮肤病及其病情活动的临床意义

作者采用琼脂糖单向免疫扩散法对200例皮肤病患者血清239人次进行了CPR的测定。结果发现病情活动与缓解两者之间的CRP值,在某些皮肤病差异高度显著性P<0.005,在SLE显著性差异P<0.05,硬皮病和皮肌炎则差异无显著性P>0.05。经治疗缓解的某些感染性皮肤病,CRP值是正常的。急性感染性疾病的CRP值是显著地增高。     

我国虫媒性皮肤病及其治疗

由医学节肢动物引起的皮肤损伤及皮肤病正逐渐引起重视。现就一些常见的由医学节肢动物引起的病征及其对策叙述如下。1　螨类引起的皮肤病1 1　疥疮　本病由寄生于人体的人疥螨成虫期引起的皮肤损伤。在我国主要分布于南方一些省市及自治区。成虫寄生于皮肤之表皮角质层间 ,啮食角质组织 ,并以其附肢在皮下开凿一条与体表平行而纡曲的隧道。故而局部的皮损表现为淡红色小丘疹 ,小水疱及隧道。隧道的盲端常有虫体隐藏 ,其呈针尖大小的灰白色小点。局部剧痒是疥疮的最突出症状 ,尤其夜晚更甚。常因剧痒抓挠而继发感染后出现脓疮 ,毛囊炎或疖肿…     

Penile skin diseases

Many dermatoses become manifest in the genital region. Some of them are specific for this anatomical site; other lesions of the penis are associated with systemic dermatological diseases. Medical history, clinical inspection of the whole integument and optional microbiological or histological examination of the lesions will lead to a correct diagnosis. Dermatoses of the penis (glans penis and/or prepuce) may be symptoms of general diseases or specific alterations of the genital region. The differential diagnoses of penile dermatoses include infections, balanitides, neoplastic diseases, trauma, papulosqamous or systemic diseases, fixed drug reactions, allergic or irritant contact dermatitis and miscellaneous lesions. Since andrologists pay special attention to the inspection and palpation of the male genital region, they should possess knowledge of dermatologically relevant penile lesions.