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111.
阴茎背深静脉包埋术治疗勃起功能障碍5例 总被引:8,自引:2,他引:6
目的 :评价阴茎背深静脉包埋术治疗勃起功能障碍 (ED)的疗效。 方法 :对 3例静脉性和 2例动静脉混合性ED病人施行阴茎背深静脉包埋术 ,术后随访疗效。 结果 :术后 2个月首次随访 ,3例静脉性ED病人获得满意性交 ,2例动静脉混合性ED病人基本能勃起 ,口服西地那非 5 0mg后可以完成性交。 5例术后随访 3~ 12个月(平均 7个月 )保持以上疗效。 结论 :阴茎背深静脉包埋术创伤小 ,几乎无并发症 ,是治疗静脉性ED的有效疗法 相似文献
112.
Shunichi Takaya MD Shunzaburo Iwatsuki Takashi Noguchi Hisaaki Koie Iman Zaghloul Raman Venkataramanan Thomas E. Starzl 《Surgery today》1989,19(1):49-56
The influence of experimentally induced hepatic dysfunction on the pharmacokinetics of Cyclosporine A (CsA) was determined
in dogs. The pharmacokinetics of oral (PO) and intravenous (IV) CsA were studied before and after 70 per cent hepatectomy
or complete bile duct ligation (CBDL). Changes in liver function were monitored by serial measurements of serum bilirubin,
and by the maximum removal rate (Rmax) and plasma disappearance rate (ICG-K) of indocyanine green (ICG). Concentrations of
CsA in whole blood were measured by HPLC. Seventy per cent hepatectomy caused significant liver dysfunction: the ICG-Rmax
decreased by 47.7±7.1 per cent (mean±SD) and the ICG-K decreased by 61.3±9.7 per cent during the first week after hepatectomy.
At the same time, the systemic clearance (CLs) of IV-CsA decreased by 43.9±8.2 per cent, the area under the concentration
curve (AUC) of IV-CsA increased by 35.4±20.8 per cent and the bioavailability of CsA decreased by 26.4±14.8 per cent. CBDL
also induced significant liver dysfunction: the ICG-Rmax decreased by 39.1±12.8 per cent and the ICG-K decreased by 65.6±3.6
per cent in the second week after the operation. During the same period, the AUC of PO-CsA decreased by 69.9±10.7 per cent
and the bioavailability of CsA also decreased markedly by 73.9±15.6 per cent. These data indicate that hepatic impairment
significantly influences the pharmacokinetics of CsA, not only by the changes in intestinal absorption, but also by those
in hepatic, metabolism. Dose adjustment is therefore necessary in the presence of hepatic dysfunction in order to maintain
an adequate blood concentration of CsA without causing side effects.
This research was performed in the Department of Surgery, University of Pittsburgh Health Center, University of Pittsburgh,
USA 相似文献
113.
114.
Shuji Seki MD 《Surgery today》1987,17(2):123-129
The ratio of PaO2 to FiO2 was often low (300 or less) in four patients with complications of hyperosmolar hyperglycemic non-ketotic diabetic coma (HHNKDC)
following open heart surgery. Four of our patients had poor oxygenation and subsequent spontaneous recovery from in the immediate
post-operative period, although HHNKDC occurred only in one during this period. In the 3 others, poor oxygenation without
accompanying HHNKDC lasted for 1–6 days and HHNKDC developed about 2 weeks after open heart surgery at time when poor oxygenation
reoccurred. If a working diagnosis of congestive heart failure was made only on the basis of the most common probability,
and the fluid supply was restricted, HHNKDC would readily occur or be aggravated by the dehydration iatrogenically produced.
It is thus concluded that HHNKDC should be included in diagnoses for pulmonary dysfunction. 相似文献
115.
Men with erectile problems seen for a comprehensive urology-department-based medical and psychological evaluation were sent questionnaires 2 to 3 years later. A representative sample of 99 (52%) responded. The majority (51%) has taken no action and reported that their sexual function was no better. Patients were more likely to comply with a recommendation for sex therapy than with one for a penile prosthesis. This was related to their attitude towards mental health professionals. These findings suggest the need for more knowledge of patient psychology and expectations.These data were presented in preliminary form at the Tenth Meeting of the International Academy of Sex Research, Cambridge, England, September 1984. 相似文献
116.
1型糖尿病患者勃起功能障碍的患病情况及相关因素分析 总被引:2,自引:0,他引:2
目的探讨1型糖尿病(T1DM)患者勃起功能障碍(ED)的患病情况及相关影响因素。方法收集182例已婚男性T1DM患者,用无记名问卷形式根据国际勃起功能指数问卷进行自我评分。并对年龄、病程、糖化血红蛋白(HbA1c)、睾酮、尿微量白蛋白排泄量、肾功能、血压、吸烟史、饮酒史、应用药物等因素进行调查,分析其与ED的关系。结果T1DM患者ED患病率为37.36%(68/182)。Logistic逐步回归分析结果显示,病程、年龄、HbA1c、收缩压、尿微量白蛋白排泄量与T1DM患者ED发生独立相关,病程增加5年、年龄增加10岁、HbA1c增加2%、收缩压增加4kPa及尿微量白蛋白排泄量的OR值分别为1.6275、1.1613、2.4211、2.3715、1.5234,P均〈0.01。结论加强对T1DM患者ED高危因素的关注和定期检测,有助于早期发现ED。 相似文献
117.
J C Henry T van Amelsvoort R G Morris M J Owen D G M Murphy K C Murphy 《Neuropsychologia》2002,40(5):471-478
Velo-cardio-facial syndrome (VCFS) is associated with deletions on the long arm of chromosome 22, mild intellectual disability, poor social interaction and a high prevalence of psychosis. However, to date there have been no studies investigating the neuropsychological functioning of adults with VCFS. We compared 19 adults with VCFS with 19 age, gender and IQ matched controls using a comprehensive neuropsychological battery. Compared to controls, adults with VCFS had significant impairments in visuoperceptual ability (Visual Object and Space Perception Battery), problem solving and planning (Tower of London) and abstract and social thinking (Comprehension WAIS-R). It is likely that haploinsufficiency (reduced gene dosage) of a neurodevelopmental gene or genes mapping to chromosome 22q11 underlies the cognitive deficits observed in individuals with VCFS. 相似文献
118.
119.
The efficacy of betanecholchloride in the postoperative treatment of bladder dysfunction is controversial. We therefore performed
a comparative study on the effect of this therapy for the prophylaxis of detrusor hypotonia after Wertheim-Meigs operation.
Forty patients with cervical cancer FIGO stage Ib/IIa were divided into two study groups. The control group (24 patients)
only received betanecholchloride if the residual urine persisted above 50 ml after the 10th postoperative day. The study group
(16 patients) received 50 mg betanecholchloride three times a day from the 3rd postoperative day onward. In this group postoperative
catheter treatment, and consequently hospital stay, were significantly shorter (9.6 versus 13.3 days and 15.5 versus 18.6
days). The residual urinary volume normalized faster (8.0 versus 13.0 days) and the rate of cystitis was lower (18.8 versus
25%). According to our study, a prophylactic application of the parasympathomimetic drug betanecholchloride diminishes postoperative
complications associated with bladder dysfunction after Wertheim-Meigs operation.
EDITORIAL COMMENT: Bladder dysfunction plays an important role after radical hysterectomy. The authors present data indicating
improved and quicker resumption of bladder function following radical hysterectomy with early administration of betanecholchloride,
versus use of the medication only when indicated by elevated postvoid residual. Although the study is not a double-blinded
placebo-controlled trial, the patients who received beta-necholchloride from postoperative day 3 had significantly decreased
postoperative catheter treatment, earlier resumption of adequate bladder emptying defined as a postvoid residual of less than
50 ml, decreased incidence of bladder infection and shorter hospital stay. This information is encouraging for this subset
of patients, who characteristically are at high risk for long-term bladder dysfunction. Further studies in this area are needed
to clarify therapeutic options to improve patients’ quality of life, specifically in regard to bladder function following
treatment of their cancer. 相似文献
120.
D. Dickerson B. Adams G. Engelbrecht G. Boltman R. Hickman D. Kahn 《Transplant international》1992,5(Z1):S63-S64
The precise cause of allograft dysfunction after renal transplantation often cannot be established by non-invasive means. In clinical practice, radionuclide scans form an integral part of the clinician's armamentarium in the assessment of these patients [1, 2]. Unfortunately, in the clinical setting more than one pathological process may be responsible for the impaired function, making it difficult to correlate the scan appearances with the pathology. In this study in rats we compared the renal DTPA scan appearances of the various pathological processes which may cause renal allograft dysfunction in the immediate post-transplant period. 相似文献