腹腔镜、胆道镜、胃镜三镜联合治疗胆囊结石合并胆总管结石的临床应用(附30例报告)

目的:探讨腹腔镜胆囊切除(laparoscopic cholecystectomy,LC)、胆总管探查+术中胃镜辅助放置鼻胆管引流、胆总管一期缝合术治疗胆囊结石并胆总管结石的临床应用价值。方法:回顾分析2011年6月至2013年7月为30例患者行LC+胆道镜胆总管探查+术中胃镜辅助放置鼻胆管引流+胆总管一期缝合术的临床资料。结果:30例手术均获成功,无一例中转开腹。手术时间110~160 min,平均(137±19)min;术中出血量30~80 ml,平均(56±16)ml;术后肠功能恢复时间24~48 h,平均(40±8)h;术后无严重并发症发生;术后住院7~9 d,平均(8±1)d。随访3~28个月,平均(17±8)个月,未发现胆总管狭窄或结石残留。结论:腹腔镜联合胆道镜、胃镜是治疗胆囊结石合并胆总管结石的合理术式,具有安全、有效、微创、保留Oddi括约肌功能等优点,患者术后康复快,具有临床推广价值。     

腹腔镜联合胆道镜微创保胆取石术68例报告

目的:探讨联合应用腹腔镜与胆道镜行微创保胆取石术治疗胆囊结石的可行性及临床应用价值。方法:回顾分析为68例患者行微创腹腔镜联合胆道镜保胆取石术的临床资料。结果:手术时间45～90min,平均65min,术后3例脐部切口疼痛使用止痛剂。患者手术当天均可下床活动,次日进流质饮食,1～3d出院。术后无出血、胆漏、切口感染等并发症发生。门诊随访1～19个月,无结石复发。结论:腹腔镜联合胆道镜微创保胆取石术是一种安全可行的胆囊结石治疗方法,具有患者创伤小、美容效果好等优点。     

多镜联合治疗肝外胆管结石3780例

目的 探讨腹腔镜、胆道镜、十二指肠镜联合治疗肝外胆管结石的方法及疗效.方法 回顾性分析1998年3月至2010年6月兰州大学第一医院收治的3780例肝外胆管结石患者的临床资料,根据患者胆管结石不同位置和采用腹腔镜、胆道镜、十二指肠镜的情况,将患者分为"一镜"、"二镜"、"三镜"治疗组;通过患者治疗后的影像学检查和随访结果,比较3组患者治疗的成功率和并发症的发生率.结果 "一镜"治疗组1425例患者,成功率为89.54%(1276/1425),并发症发生率为6.73%(86/1276);149例治疗失败,其中83例接受"二镜"治疗、66例接受"三镜"治疗."二镜"治疗组1792例患者(含转入83例),成功率为95.93%(1719/1792),并发症发生率为4.07%(70/1719);73例治疗失败(转入"三镜"治疗组)."三镜"治疗组785例(含转入139例)患者,成功率为99.75%(783/785),并发症发生率为0.26%(2/783);2例治疗失败患者选择开腹手术治疗.结论 腹腔镜、胆道镜、十二指肠镜联合应用治疗肝外胆管结石可以优势互补,明显提高结石取尽成功率,降低术后并发症的发生率.

Abstract：

Objective To investigate the efficacy of combined application of laparoscope and multiple endoscopes for the treatment of extra-hepatic bile duct stones.Methods The clinical data of 3780 patients with extra-hepatic bile duct stones who were admitted to the First Hospital of Lanzhou University from March 1998 to June 2010 were retrospectively analyzed.According to the condition of bile duct stones,laparoscope,choledochoscope and duodenoscope were applied separately or combinately.All patients were divided into A,B and C groups.Patients in group A were treated by laparoseopy,choledochoscopy or duodenoscopy;patients in group B were treated by choledochoscopy+duodenoscopy.duodenoscopy+laparoscopy or laparoscopy+choledochoscopy;patients in group C were treated by laparoscopy+duodenoscopy+choledochoscopy.The efficacies of different treatment approaches were analyzed by comparing the results of imaging examination and follow-up.Results The curative rate and complication rate of the group A were 89.54%(1276/1425)and 6.73%(86/1276),respectively.Of the 149 patients in the group A who were failed in the treatment,83 patients were transferred to the group B,and 66 patients were transferred to the group C.The curative rate and complication rate of the group B(including 83 patients transferred from the group A)were 95.93%(1719/1792)and 4.07%(70/1719),respectively,and 73 patients who were failed in the treatment were transferred to the group C.The curative rate and complication rate of the group C(including 139 patients transferred from the group C)were 99.75%(783/785)and 0.26% (2/783),respectively,and 2 patients who were failed in the treatment received open surgery.Conclusion Combined application of laparoscope and endoscopes could raise the success rate of stone clearance and decrease the postoperative complications.     

腹腔镜和胆道镜双镜联合治疗胆总管结石临床疗效观察

目的探讨腹腔镜联合纤维胆道镜双镜治疗胆总管结石的临床疗效。方法选取2011年11月至2013年4月我院行手术治疗胆总管结石患者72例,其中行腹腔镜联合胆道镜治疗40例作为观察组,开腹手术治疗32例作为对照组。观察并比较两组临床疗效结果。结果 72例手术均获成功。其中观察组在术中出血量、胃肠功能恢复时间、住院天数、术后并发症发生率方面均优于对照组(P0.05)。结论腹腔镜和胆道镜双镜联合治疗胆总管结石具有损伤小、恢复快、术中出血少、疼痛反应轻、住院时间短及术后并发症少等优点,是目前治疗胆道结石较理想的微创术式,临床上值得推广。     

腹腔镜联合胆道镜保胆取石术同期治疗胆囊结石与胆总管结石的临床体会

目的:探讨为胆囊结石、胆总管结石患者行腹腔镜联合胆道镜保胆取石术的手术疗效及临床价值。方法:将68例患者按其意愿分为两组,观察组行腹腔镜联合胆道镜保胆取石术,对照组行传统胆囊切除胆总管切开取石术,比较两组手术时间、术中出血量、住院时间、并发症发生率及术后随访情况。结果:观察组中转开腹1例,对照组中转开腹2例,两组差异无统计学意义(P=0.648);两组手术时间差异无统计学意义(P>0.05);观察组术中出血量、住院时间优于对照组,差异有统计学意义(P<0.05);两组均未发生穿孔、出血、死亡等严重并发症,急性胰腺炎均为轻度,且经及时治疗后痊愈;急性胰腺炎、肺部感染、切口感染情况两组相比差异有统计学意义(P<0.05)。术后8周复查,均无结石复发及其他相关并发症发生,术后1年,对照组发现残余结石1例,经胆道镜取石后痊愈。结论:胆囊结石、胆总管结石患者行腹腔镜联合胆道镜保胆取石术后并发症少,患者痛苦轻,双镜联合可取长补短,优势结合,充分发挥微创的治疗原则。应根据患者的病情,制定个体化诊疗方案,以减少手术并发症,提高疗效。     

腹腔镜、胆道镜引导下钬激光碎石术治疗肝内外胆管结石的临床体会

目的：探讨腹腔镜胆道镜引导下钬激光碎石治疗肝内外胆管结石的可行性。方法：回顾分析2008～2012年为45例肝内外胆管结石患者行腹腔镜胆道镜引导下钬激光碎石治疗的临床资料。结果：45例患者中3例中转开腹;42例成功完成手术,手术时间90～150 min,平均（110±16）min。术后残留结石7例,6例一次取石成功,1例两次取石成功;术后均有轻至中度肝功损害,对症治疗后痊愈;1例少量胆漏,经引流治愈,无切口感染、血栓等其他并发症发生。结论：腹腔镜、胆道镜引导下钬激光碎石术治疗肝内外胆管结石具有患者创伤小、术后康复快等优点,安全、实用。     

腹腔镜联合胆道镜保胆取石术5年回顾分析(附360例报告)

目的:探讨腹腔镜联合胆道镜保胆取石术的应用价值、适应证、手术技巧及临床疗效。方法:回顾分析2008年1月至2013年12月为360例胆囊结石患者行腹腔镜联合胆道镜保胆取石术的临床资料。结果:360例手术均获成功,术中出血量5~10 ml,平均(7.0±1.2)ml;手术时间36~176 min,平均(48.5±17.4)min。术后无残留结石、出血、胆漏、腹腔感染等并发症发生。术后住院2~3 d。随访5年,236例获得随访,随访率65.6%;其中12例结石复发,复发率5.08%。结论:腹腔镜联合胆道镜保胆取石术后复发率较低,方法简单,手术安全、可行,是保留胆囊功能的有效方法。     

The importance of postoperative choledochoscopy for management of retained biliarytract stones

From 1974-8, 808 postoperative choledochoscopy procedures, conducted by insertion of choledochofiberscope into the biliary tract through the sinus tract after the T-tube had been removed, were carried out in 292 patients at Teikyo University Hospital, Tokyo, Japan. In this series, 104 with retained biliary tract stones were encountered, and complete removal of stones was successfully carried out in 101, using postoperative choledochoscopy. Any failures of removal of retained biliary tract stones were attributed to improper insertion of the T-tube. The T-tube, of at least 18 French calibers should be inserted into the common bile duct at a right angle so as to obviate a tortuous sinus tract. The follow-up study in cases of complete extraction of the retained biliary tract stones showed that this approach is most effective. Recurrent stone with a silk nidus was found in one patient in whom postoperative choledochoscopy had been performed one year previously. Reoperation was carried out in this particular case. All other patients have remained asymptomatic. Finally, we advise routine use of postoperative choledochoscopy as an adjunct to the T-tube cholangiography, in order to prevent the possibility of retained biliary tract stones. Contents of this paper were read before the Annual Meeting of the American Society for Gastrointestinal Endoscopy, Digestive Disease Week '79 on May 22nd, 1979 in New Orleans, U.S.A.     

三孔法腹腔镜联合胆道镜保胆取石术的临床应用

目的:探讨三孔法腹腔镜联合胆道镜保胆取石术的应用价值、适应证、手术技巧及临床疗效。方法:回顾分析2010年10月至2013年6月96例胆囊结石患者的临床资料,均行三孔法腹腔镜联合胆道镜完全腹腔内微创保胆取石术。结果:96例手术均获成功,无一例中转腹腔镜胆囊切除术或腹腔外微创保胆取石术。术中出血量5~10 ml,平均(6.0±1.1)ml;手术时间98~225 min,平均(121.8±13.2)min。术后无残留结石、出血、胆漏、腹腔感染、胆总管继发结石等并发症发生。术后住院4~7d,平均(4.5±0.6)d,术后1周复查B超,无结石残留。出院后口服熊去氧胆酸、消炎利胆片3~6个月。95例患者随访4~24个月,未见结石复发,无明显消化道症状,术后3个月复查B超提示胆囊收缩功能良好。结论:三孔法腹腔镜联合胆道镜保胆取石术安全、有效,具有患者创伤小、康复快、并发症少、手术成功率高等优点,是微创保胆取石术的理想手术方法,值得推广应用。其关键是把握适应证,术后预防性用药,同时术者需熟练掌握胆道镜技术及腹腔镜下切开、缝合、打结技术。     

腹腔镜联合胆道镜、FREDDY激光治疗肝内胆管结石的临床体会

目的:探讨腹腔镜联合胆道镜、FREDDY激光治疗肝内胆管结石的应用价值。方法:回顾分析104例肝内胆管结石患者的临床资料,分别行腹腔镜手术(腹腔镜组,n=57)及开腹手术(开腹组,n=47)。对比分析两组患者手术时间、术中出血量、术后肛门排气时间、切口感染率、严重并发症发生率(胆道大出血、严重胆漏等)、术后住院时间、一期结石清除率、总结石清除率等指标。结果:腹腔镜组术中出血量、术后肛门排气时间、切口感染率、一期结石清除率、术后住院时间均优于开腹组,差异有统计学意义(P<0.05)。两组手术时间、总结石清除率及严重并发症发生率差异无统计学意义(P>0.05)。结论:腹腔镜联合胆道镜、FREDDY激光碎石术治疗肝内胆管结石具有微创、安全、可靠、有效的优势,为肝内胆管结石提供了新的治疗方式,值得推广。