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21.
A M Heyse D Vanhercke J Nimmegeers L Missault R Claeys G Hollanders L Versée 《European journal of echocardiography》2003,4(4):334-335
We describe the case of a 79-year-old woman with mitral insufficiency and a double-orifice mitral valve (DOMV), discovered by echocardiography. Transthoracic echocardiography showed two insufficiency jets. Transesophageal echocardiography revealed a DOMV. Each orifice was provided with a subvalvular apparatus. No associated congenital abnormalities were present. Our case demonstrates that even in elderly patients with a double regurgitant jet, DOMV should be suspected and assessed by transesophageal echocardiography. 相似文献
22.
R. Padovani N. Acciarri M. Giulioni R. Pantieri M. P. Foschini 《European spine journal》1997,6(5):298-303
Cavernous angiomas, also called cavernous malformations or cavernomas, are vascular hamartomas accounting for 3–16% of all angiomatous lesions of the spinal district. Although histologically identical, these vascular anomalies may exhibit different clinical behavior and radiological features, depending on their location, hinting at different managements and therapeutic approaches. The authors report 11 cases of symptomatic spinal cavernous angiomas diagnosed and surgically treated over the past 18 years. Age of patients ranged from 15–75 years; males outnumbered females. Three patients had vertebral cavernous malformations, secondarily invading the epidural space; two had pure epidural lesions; two patients had intradural extramedullary lesions, and four intramedullary lesions. Surgical removal was completely achieved in four patients with intramedullary lesions, in two with subdural extramedullary lesions, and in one with a pure epidural lesion. Subtotal excision of another one epidural and three vertebral cavernous angiomas was followed by radiotherapy. There was no morbidity related to surgery; the mean follow-up was 2 years. The outcome was excellent in two cases, good in six, and unchanged in the other three. The authors discuss the different modalities of treatment of these vascular lesions variously placed along the spine. 相似文献
23.
头面部复杂动静脉畸形的栓塞治疗 总被引:2,自引:0,他引:2
目的 研究经导管栓塞技术在头面部动静脉畸形治疗中的应用。方法 3 0例头面部动静脉畸形患者共接受 40次栓塞治疗。其中使用国产TH胶栓塞者为 18例 2 0次 ,使用进口PVA微粒栓塞者为 12例 2 0次。结果 3 0例患者均成功实行瘤灶供血动脉栓塞术。所有患者栓塞术后临床症状明显改善 ,如瘤体缩小甚至消失 ,皮温降低 ,搏动感和血管杂音减弱或消失等。术后随访3~ 6个月 ,12例复发。全部病例均无严重并发症。结论 对于头面部动静脉畸形的患者来说 ,经导管栓塞术是一种较好的非手术治疗方法 ,在栓塞剂的选择方面 ,则以PVA微粒栓塞更为理想。 相似文献
24.
Tomoyuki TAKANO Masaki OHNO Tsunekazu YAMANO Morimi SHIMADA 《Congenital anomalies》1991,31(3):129-139
Abstract This study was undertaken to elucidate the pathogenesis of the hydrocephalus and aqueductal stenosis induced by intracerebral mumps virus inoculation in suckling hamsters.
Mild ventricular dilatation became apparent after 5 days of inoculation. Focal denuding of the ependymal layer and subsequent aqueductal stenosis were observed by 14 days after inoculation. The virus antigen was detected not only in the ependymal cells and choroid plexus, but also in some neurons in the cerebral cortex, hippocampus, midbrain and cerebellum. In the cerebral aqueduct, the orderly arrangement of the cilialy clusters was destroyed on the 5th day after inoculation. After 10 days, proliferation of GFAP positive cells was noticed around the cerebral aqueduct and subsequently caused aqueductal stenosis. In the advanced state of hydrocephalus, the cerebellum was displaced downward and showed an elongated, atrophic and sleevelike structure similar to the Arnold-Chiari malformation. It was suggested that the extensive damage of the ependymal cilia may account for early ventricular dilatation, and subsequent aqueductal stenosis with glial proliferation is the main cause of the advanced hydrocephalus. It has not yet been determined whether the mumps virus can pass through the human placenta or not. If it can, however, our results strongly suggest that mumps virus infection in the human fetus will cause congenital hydrocephalus. 相似文献
Mild ventricular dilatation became apparent after 5 days of inoculation. Focal denuding of the ependymal layer and subsequent aqueductal stenosis were observed by 14 days after inoculation. The virus antigen was detected not only in the ependymal cells and choroid plexus, but also in some neurons in the cerebral cortex, hippocampus, midbrain and cerebellum. In the cerebral aqueduct, the orderly arrangement of the cilialy clusters was destroyed on the 5th day after inoculation. After 10 days, proliferation of GFAP positive cells was noticed around the cerebral aqueduct and subsequently caused aqueductal stenosis. In the advanced state of hydrocephalus, the cerebellum was displaced downward and showed an elongated, atrophic and sleevelike structure similar to the Arnold-Chiari malformation. It was suggested that the extensive damage of the ependymal cilia may account for early ventricular dilatation, and subsequent aqueductal stenosis with glial proliferation is the main cause of the advanced hydrocephalus. It has not yet been determined whether the mumps virus can pass through the human placenta or not. If it can, however, our results strongly suggest that mumps virus infection in the human fetus will cause congenital hydrocephalus. 相似文献
25.
An atypical variant of reflex sympathetic dystrophy (RSD) is presented in a 45 year old female with a vascular malformation
of the right arm and chest wall. The mechanism was thought to be compression of the brachial plexus by the malformation. The
unique scintigraphic features of this presentation of RSD in the ulnar arterial distribution are illustrated. 相似文献
26.
Summary Intracranial haemorrhage due to rupture of an arteriovenous malformation (AVM) during pregnancy is a rare but serious condition that warrants prompt recognition. Once the diagnosis is made, the management is primarily based on neurosurgical rather than obstetric considerations. Due to its rarity, no definitive guidelines exist, and the best time to perform elective surgery (i.e., at presentation or at completion of the pregnancy) is ill-defined. This report describes three patients recently treated at our institution who had AVMs that ruptured during pregnancy. These cases well summarize the difficulties encountered in treating such patients. The diagnostic as well as the therapeutic implications of this condition are discussed. 相似文献
27.
Oguzkan Sürücü Ulrich Sure Sabine Gaetzner Sonja Stahl Ludwig Benes Helmut Bertalanffy Ute Felbor 《Child's nervous system》2006,22(11):1461-1464
Introduction and background A 3-year-old Bosnian girl with a large symptomatic brainstem and multiple supratentorial cavernous angiomas, who underwent neurosurgical treatment, is presented. As multiple cavernomas are more common in familial cases, genetic analyses and neuroradiological imaging were performed in the patient and her parents to see whether there was any evidence for inheritance. This information is important for genetic counseling and provision of medical care for at-risk relatives. Currently, no recommendation is available on how to manage these cases.Results Genetic analyses demonstrated a novel CCM1 frameshift mutation (c.1683_1684insA; p.V562SfsX6) in the child and the asymptomatic 27-year-old mother. Sensitive gradient-echo magnetic resonance imaging of the mother revealed multiple supratentorial lesions, whereas analogous imaging of the father showed no pathological findings.Conclusion This case exemplifies that seemingly sporadic cases with multiple lesions might well be hereditary and that presymptomatic genetic testing of family members may identify relatives for whom clinical and neuroradiological monitoring is indicated. 相似文献
28.
脑动静脉畸形实验动物模型的建立 总被引:1,自引:1,他引:0
脑动静脉畸形是一种比较常见的严重威胁人们生命安全和生存质量的脑血管疾病,目前人们主要是通过尸体解剖以及CT、MRI等影像学的方法认识。近年来,学者们应用各种动物模型来研究脑动静脉畸形的血流动力学,病理生理学以及脑动静脉畸形栓塞材料的评估,栓塞后临床疗效评价,放射照射剂量对脑动静脉畸形的影响等。本文就脑动静脉畸形实验动物的常用种类,动物模型的建立方法以及动物模型的实际应用进行了综述。 相似文献
29.
经皮血管内采用氰基丙烯酸异丁脂(IBCA)栓塞治疗38例颅内动静脉畸形(AVM)病人。其中8例达到100%完全栓塞,栓塞面积大于75%的10例,大于50%者11例;余下9例栓塞面积小于50%,19例以出血为首发症状,11例以癫痫为首发症状,6例神经功能障碍,2例以头痛为主要症状。栓塞术后发生并发症5例,占13%,无死亡病例。本文讨论了超选插管技术问题、Amytal试验假阴性、导管粘连及正常灌注压突破。 相似文献
30.
目的:总结X刀治疗脑内病变的长期随访结果.方法:对283例X刀治疗的脑瘤和脑血管畸形患者进行临床和影像学随访,随访时间为1~8年,平均(2.05±4.66)年.结果:82例转移瘤消失35例(42.7%),缩小28例(34.1%),无变化11例(13.4%),增大8例(9.8%);61例胶质瘤消失10例(16.4%),缩小19例(31.1%),无变化16例(26.2%),增大16例(26.2%);55例动静脉畸形消失29例(52.7%),缩小20例(36.4%),无变化6例(10.9%);17例海绵状血管瘤缩小4例(23.5%),无变化13例(76.5%);35例脑膜瘤消失5例(14.3%),缩小15例(42.9%),无变化13例(37.1%),增大2例(5.7%);12例神经鞘瘤消失3例(25.0%),缩小6例(50.0%),无变化2例(16.7%),增大1例(8.3%);10例生殖细胞瘤消失8例(80.0%),缩小2例(20.0%);11例其他肿瘤消失2例(18.2%),缩小4例(36.4%),无变化4例(36.4%),增大1例(9.0%).影像检查还发现病灶有坏死表现99例,囊性变19例,周边环状强化73例,胶质细胞增生20例,暂时性反应性肿大23例,放射性脑水肿28例.结论:X刀对小型脑肿瘤和血管畸形是一种安全有效的治疗方法,X刀治疗的主要并发症是放射性脑水肿. 相似文献