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81.
随着中医药对外交流的深入开展和世界对中药认识的加深,中医药说明书的翻译问题逐渐引起了重视。为了达到对外宣传中医药并让世界了解中医药的目的,本文从功能文体学指导下的科技文体出发,通过探讨中药说明书的翻译译例,总结出对中药说明书的翻译策略,以期为中医药的国际化贡献绵薄之力。 相似文献
82.
Inna G. Ovsyannikova Iana H. Haralambieva Robert A. Vierkant Megan M. O’Byrne Gregory A. Poland 《Human immunology》2013
The role of polymorphisms within the antiviral tripartite motif (TRIM) genes in measles vaccine adaptive immune responses was examined. A limited association was found between TRIM5 (rs7122620) and TRIM25 (rs205499) gene polymorphisms and measles-specific antibody levels. However, many associations were found between TRIM gene SNPs and variations in cellular responses (IFN-γ Elispot and secreted cytokines IL-2, IL-6, IL-10, IFN-γ, and TNF-α). TRIM22 rs2291841 was significantly associated with an increased IFN-γ Elispot response (35 vs. 102 SFC per 2 × 105 PBMC, p = 0.009, q = 0.71) in Caucasians. A non-synonymous TRIM25 rs205498 (in LD with other SNPs, r2 ? 0.56), as well as the TRIM25 AAAGGAAAGGAGT haplotype, was associated with a decreased IFN-γ Elispot response (t-statistic −2.32, p = 0.02) in African-Americans. We also identified polymorphisms in the TRIM5, TRIM22, and TRIM25 genes that were associated with significant differences in cytokine responses. Additional studies are necessary to replicate our findings and to examine the functional consequences of these associations. 相似文献
83.
《Early child development and care》2012,182(1-4):83-99
Due to increasing availability and sophistication of relatively inexpensive computer hardware, the applications of computers in the teaching and learning process in our schools are expanding. One of the more recent applications is Computer Management of Instruction (CMI), which has been selected as the focus of this article. The author's background experience includes working as a primary developer of a CMI software package supported by the Arkansas State Department of Education. It is hoped that these experiences, both as a user and as a developer of software, will enable the author to share some insights concerning the preparation necessary for using CMI, the general structure of a CMI system, and some features a user might expect to find as part of a CMI system. The system developed through the ADE project is called Computer‐Assisted Instructional Management (C‐AIM), and it will be used as an example in this article. 相似文献
84.
我们应用小鼠非麻醉状态下Ⅲ度烧伤模型,观察烧伤后6天细胞免疫功能的变化及黄芪多糖(APS)体内应用对烧伤后细胞免疫功能的影响。结果显示:烧伤后6天小鼠的脾脏指数和胸腺指数降低,脾细胞的T淋巴细胞转化、白介素2(IL-2)的产生均明显受抑;烧伤小鼠血清、巨噬细胞对T淋巴细胞转化的抑制作用明显增强,抑制性T细胞(Ts)的抑制指数也高于正常。APS经腹腔注射(250mg/kg,每天一次,连续5天)不仅可明显提高正常小鼠的脾脏指数和胸腺指数,还可使烧伤小鼠的脾脏指数和胸腺指数恢复正常;APS体内应用还可纠正烧伤小鼠T淋巴细胞转化,IL-2产生的受抑状态,并可使烧伤小鼠血清、巨噬细胞及Ts的抑制活性降低至正常水平。上述结果提示:烧伤小鼠细胞免疫功能受抑与烧伤后血清、巨噬细胞及Ts的抑制作用有关;黄芪多糖体内治疗可降低烧伤后血清、巨噬细胞、Ts的抑制活性,恢复烧伤后受损的细胞免疫功能 相似文献
85.
《Vaccine》2018,36(7):986-996
BackgroundInfants with history of prematurity (<37 weeks gestation) and low birth weight (LBW, <2500 g) are at high risk of infection due to functional immaturity of normal physical and immunological defense mechanisms. Despite current recommendations that infants with history of prematurity/LBW should receive routine immunization according to the same schedule and chronological age as full-term infants, immunization is often delayed.MethodsHere we summarize 10 clinical studies and 15 years of post-marketing safety surveillance of GSK’s hexavalent vaccine (DTPa-HBV-IPV/Hib), a combined diphtheria-tetanus-acellular-pertussis-hepatitis-B-inactivated-poliovirus-Haemophilus influenzae-type-b (Hib) conjugate vaccine, when administered alone, or co-administered with pneumococcal conjugate, rotavirus, and meningococcal vaccines and respiratory syncytial virus IgG to infants with history of prematurity/LBW in clinical trials.ResultsAt least 92.5% of infants with history of prematurity/LBW as young as 24 weeks gestation in clinical studies were seropositive to all vaccine antigens after 3-dose primary vaccination with GSK’s hexavalent DTPa-HBV-IPV/Hib vaccine, with robust immune responses to booster vaccination. Seropositivity rates and antibody concentrations to hepatitis B and Hib appeared lower in infants with history of prematurity/LBW than term infants. Between 13–30% of medically stable infants with history of prematurity developed apnea after vaccination with GSK’s hexavalent DTPa-HBV-IPV/Hib vaccine; usually after dose 1. The occurrence of post-immunization cardiorespiratory events appears to be influenced by the severity of any underlying neonatal condition. Most cardiorespiratory events resolve spontaneously or require minimal intervention. GSK’s hexavalent DTPa-HBV-IPV/Hib vaccine was well tolerated in co-administration regimens.ConclusionGSK’s hexavalent DTPa-HBV-IPV/Hib vaccine alone or co-administered with other pediatric vaccines has a clinically acceptable safety and immunogenicity profile when used in infants with history of prematurity/LBW for primary and booster vaccination. Additional studies are needed in very premature and very LBW infants. However, currently available data support using GSK’s hexavalent DTPa-HBV-IPV/Hib vaccine to immunize infants with history of prematurity/LBW according to chronological age. 相似文献
86.
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88.
Ichiro Wakabayashi 《Diabetes & Metabolic Syndrome: Clinical Research & Reviews》2018,12(6):1013-1017
Aims
Cardiometabolic index (CMI), calculated as the product of waist-to-height ratio and triglycerides-to-HDL cholesterol ratio, has been proposed as a discriminator of diabetes and has been reported to be associated with progression of atherosclerosis. The purpose of this study was to determine the relationship between alcohol drinking and CMI in men with diabetes.Methods
The subjects were Japanese male workers aged from 35 to 65 years with diabetes mellitus (n?=?1411). The subjects were divided by average daily alcohol consumption (g ethanol/day) into 4 categories of alcohol drinking (nondrinkers; light drinkers, < 22; moderate drinkers, ≥ 22 and < 44; heavy drinkers, ≥ 44). CMI and variables comprising CMI were compared in the nondrinker and each of the drinker groups. Age, habits of smoking and regular exercise, and a present history of medication therapy for diabetes were adjusted in each analysis.Results
Log-transformed CMI was significantly lower in light and moderate drinkers than in nondrinkers. Waist-to-height ratio was significantly lower in moderate drinkers than in nondrinkers, while log-transformed triglycerides was significantly higher in heavy drinkers than in nondrinkers. HDL cholesterol tended to be higher with an increase of alcohol consumption. Odds ratios with their 95% confidence intervals vs. nondrinkers for high CMI were 0.53 (0.36–0.78) in light drinkers, 0.61 (0.46–0.80) in moderate drinkers, and 0.74 (0.55–1.00) in heavy drinkers.Conclusions
In men with diabetes, CMI is lower in light-to-moderate drinkers than in nondrinkers, and this results mainly from a positive association between alcohol drinking and HDL cholesterol. 相似文献89.
90.
Thomas D. Bishop 《Early child development and care》1988,32(1):83-99
Due to increasing availability and sophistication of relatively inexpensive computer hardware, the applications of computers in the teaching and learning process in our schools are expanding. One of the more recent applications is Computer Management of Instruction (CMI), which has been selected as the focus of this article. The author's background experience includes working as a primary developer of a CMI software package supported by the Arkansas State Department of Education. It is hoped that these experiences, both as a user and as a developer of software, will enable the author to share some insights concerning the preparation necessary for using CMI, the general structure of a CMI system, and some features a user might expect to find as part of a CMI system. The system developed through the ADE project is called Computer-Assisted Instructional Management (C-AIM), and it will be used as an example in this article. 相似文献