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201.
The records of 1018 patients with low back pain in a tertiary spine referral practice were reviewed. One hundred thirty-nine out of 1018 (13.6%) underwent technetium-99m planar bone scanning as part of their investigation. Seventy-three out of 139 scans (52%) showed increased uptake in some area, but only 27 out of 139 (19.4%) showed increased uptake specifically in the low back. Scans consistently yielded no findings with reference to the back when the prescan diagnosis was spinal stenosis, lumbar pain syndrome, herniated nucleus pulposus, or postlaminectomy syndrome. Some scans gave positive findings in patients with a diagnosis of degenerative disc disease, pseudarthrosis, spondylolisthesis, fracture, infection, metabolic disorder, or tumor. Positive scans were generally obtained early after presentation (within 3 months) and negative scans obtained later (after 6 months), suggesting that clinical suspicion is still the main indication for early scanning. Planar bone scanning was helpful in both diagnosis and therapeutic decisionmaking in many conditions. 相似文献
202.
目的 :观察骨延长术对血清微量元素的影响。方法 :采用实验家兔 6只 ,造成左胫骨中段骨延长模型 ,定期耳缘静脉采血。原子吸收分光光度仪测定血清中锌、铜、铁的含量。结果 :骨延长术后血清铜元素含量呈上升趋势 ,血清铁、锌元素含量明显下降。在延长结束后 5d时与术前比较有明显差别 (P <0 .0 5 )。结论 :骨延长术后 ,血清铁、锌元素含量呈阶段性下降 ,适时予以补充 ,有利于骨组织的修复。 相似文献
203.
[目的]观察补肾密骨片结合经皮自体骨髓移植对骨折延迟愈合治疗后的骨密度和生物力学性能影响。[方法]预制新西兰大耳白兔骨延迟愈合模型,将75只兔随机分为四组:A组20只,饲料中加入补肾密骨片,骨延迟愈合区注入自体红骨髓2ml;B组20只,饲料中加入补肾密骨片,骨延迟愈合区不注入自体红骨髓;C组20只,饲料中不加补肾密骨片,骨延迟愈合区注入自体红骨髓;D组15只,造成骨延迟愈合模型后,饲料中不加补肾密骨片,骨延迟愈合区不注人自体红骨髓。治疗后12周处死动物取材,行骨密度及生物力学测试。[结果]骨密度及生物力学测试均显示A组骨愈合优于B、C、D组。[结论]补肾密骨片结合经皮自体骨髓移植治疗骨折延迟愈合的骨组织的骨密度及生物力学强度优于单一骨髓移植或中药治疗。 相似文献
204.
G. Negri S. Grassi M. Zappia S. Cappabianca P. F. Rambaldi L. Mansi 《Journal of orthopaedics and traumatology》2006,7(4):176-181
Transient osteoporosis is an infrequent condition of uncertain etiology with pain, limited range of motion and radiographic
evidence of osteoporosis affecting one or more joints. It is self-limited, reversible and can involve only the hip (transient
osteoporosis of the hip, TOH) or, less frequently, one or more joints contemporaneously or at different times (regional migratory
osteoporosis, RMO). We studied four men with transient osteoporosis, including two with TOH and two with RMO. All patients
underwent a standard radiographic work-up of the affected joints, arteriovenous Doppler US, computed tomography, magnetic
resonance imaging (MRI) and three-phase bone scanning. In all patients, symptoms were related to bone marrow edema demonstrated
at MRI and to a transitory regional arterial hyperflow observed at the early scintigraphic analysis. On the basis of our observations,
we hypothesize that regional arterial hyperflow may be the cause of the bone marrow edema and therefore of the transient osteoporosis. 相似文献
205.
通过介绍国外人体骨铅测量的历史背景、多种器官铅含量的对比以及体内X射线荧光技术(In vivoXRF)测定骨铅研究的近期发展状况,探讨人体骨铅含量体内X射线荧光非损伤性测定的重要意义。 相似文献
206.
J. BYROM G. DOUCE† P.W. JONES‡ H. TUCKER J. MILLINSHIP K. DHAR & C.W.E. REDMAN 《International journal of gynecological cancer》2006,16(1):253-256
The reliability and applicability of colposcopically directed cervical punch biopsy was assessed in a sample of 170 paired punch and large loop excision of cervical transformation zone (LLETZ) specimens obtained from previously untreated women who had been selected for treatment on the basis of cytology and/or colposcopic findings and in whom the entire cervical transformation zone was visible. A single punch biopsy was taken immediately before the LLETZ, and all the specimens were reviewed by a single pathologist. Nine (5.3%) punch biopsies were inadequate. In terms of whether or not there was cervical intraepithelial neoplasia (CIN), the chance-corrected kappa analysis rated overall agreement as poor (kappa = 0.21, 95% confidence limits 0.02-0.39), whereas in terms of histologic grade, it was fair to moderate (kappa = 0.32, 95% confidence limits 0.23-0.42). Punch biopsy tended to underestimate the disease. The sensitivity and specificity of colposcopically directed punch biopsy for the detection of high-grade CIN was 74% and 91%, respectively, with positive- and negative predictive values of 97% and 48%, respectively. Two microinvasive and two intraepithelial glandular lesions were missed on punch biopsy. Punch biopsy should be avoided when high-grade disease is suspected. 相似文献
207.
MASAAKI SHIMATANI KAZUYUKI TSUJI YOSHIYA AZE SHIN YAMAMOTO NOBUYUKI SHIBATANI YOSHIHITO IMAI SHOICHIROH TAKAMIDO YOSHITSUGU KUBOTA KAZUICHI OKAZAKI 《Journal of gastroenterology and hepatology》2006,20(1):117-125
Background and Aims: Increased numbers and enhanced functions of peripheral neutrophils have been observed in obstructive jaundice. However, the effects of obstructive jaundice on the bone marrow, that is neutrophil production and acquisition of neutrophil chemotactic activity, have been poorly understood. In the present study, differentials of bone marrow cells and chemotactic activity of bone marrow neutrophils were evaluated in bile duct-obstructed rats.
Methods: Male Wistar rats underwent either bile duct obstruction for 10 days or bile duct obstruction for 4 days followed by 6 days' internal biliary drainage. Differentials of peripheral blood and bone marrow cells were sequentially determined. Chemotactic activity of peripheral and bone marrow neutrophils was evaluated with a modified Boyden method using interleukin-8 (recombinant rat Gro-β) as a chemoattractant.
Results: Numbers of peripheral neutrophils significantly increased after bile duct obstruction. Significant increases in the myeloid/erythroid (M/E) ratio of bone marrow cells were observed after bile duct obstruction. The neutrophil proliferative pool (promyelocytes and myelocytes) increased initially, followed by an increased neutrophil storage pool (metamyelocytes, bands, and segmented neutrophils). The M/E ratio as well as the neutrophil proliferative and storage pools normalized after internal biliary drainage. Chemotactic activity was enhanced in both peripheral and bone marrow neutrophils after bile duct obstruction, and enhanced chemotaxis was alleviated with internal biliary drainage.
Conclusion: The present results strongly suggest the principal role of the bone marrow in increasing the number of neutrophils and their chemotactic activity during obstructive jaundice. 相似文献
Methods: Male Wistar rats underwent either bile duct obstruction for 10 days or bile duct obstruction for 4 days followed by 6 days' internal biliary drainage. Differentials of peripheral blood and bone marrow cells were sequentially determined. Chemotactic activity of peripheral and bone marrow neutrophils was evaluated with a modified Boyden method using interleukin-8 (recombinant rat Gro-β) as a chemoattractant.
Results: Numbers of peripheral neutrophils significantly increased after bile duct obstruction. Significant increases in the myeloid/erythroid (M/E) ratio of bone marrow cells were observed after bile duct obstruction. The neutrophil proliferative pool (promyelocytes and myelocytes) increased initially, followed by an increased neutrophil storage pool (metamyelocytes, bands, and segmented neutrophils). The M/E ratio as well as the neutrophil proliferative and storage pools normalized after internal biliary drainage. Chemotactic activity was enhanced in both peripheral and bone marrow neutrophils after bile duct obstruction, and enhanced chemotaxis was alleviated with internal biliary drainage.
Conclusion: The present results strongly suggest the principal role of the bone marrow in increasing the number of neutrophils and their chemotactic activity during obstructive jaundice. 相似文献
208.
Abstract
Background: In recent years, biomaterials are being found and frequently utilized in bone defects. They have also gained significant precedence
in hand surgery.
Objectives: The respective requirements for such replacement material will be cited and acknowledged in this article. The individual material
groups will also be referred to in this review. An introduction to some of the customary bone replacement materials will be
cited and concluded with a corresponding recommendation.
Conclusion: The implantation of autologous cancellous bone is still regarded today as the “gold standard”. Nevertheless, the usage of
bone replacement material can be an enormous advantage in certain indications.
The original article can be found online at
There was an error in the author’s affiliation and the address for correspondence was incomplete. Please note the correct
institution and complete address:
Department of Orthopedics and Traumatology, Hand-, Foot- and Reconstructive Surgery, Kreiskrankenhaus Gummersbach GmbH, Germany.
Alexander von Friesen, MD Department of Orthopedics and Traumatology, Hand-, Foot- and Reconstructive Surgery Kreiskrankenhaus
Gummersbach GmbH Wilhelm-Breckow-Allee 20 51643 Gummersbach Germany Phone (+49/2261) 171-575, Fax -449 e-mail: Friesen@kkh-gummersbach.de 相似文献
209.
210.
Michelle Lucinda DeOliveira M.D. Tarcisio Triviño M.D. Ph.D. Gaspar de Jesus Lopes Filho M.D. Ph.D. 《Journal of gastrointestinal surgery》2006,10(8):1140-1143
Carcinoma of the papilla of Vater is classified as periampullary cancer representing 5% of all gastrointestinal tract malignancies.
Early and accurate diagnosis is important for those patients with a tumor of the papilla, as the prognosis is more favorable
than in other periampullary neoplasms. Endoscopically obtained biopsies from suspicious papillae can detect an early tumor,
although even for skilled pathologists it is often difficult to differentiate carcinomas from noninvasive lesions on the basis
of forceps biopsies. The purpose of this study was to assess the preoperative diagnostic accuracy of duodenoscopy appearance
and biopsy in all cases with suspicion of tumor. Thirty patients with suspicion of carcinoma of the papilla of Vater and with
final diagnosis established by pancreatoduodenectomy were included in this retrospective study. In each case, a comparison
was made between endoscopic biopsy and duodenoscopic appearance. Duodenoscopic appearance sensitivity and accuracy for malignancy
were 86% and 83%, respectively, whereas endoscopic biopsy sensitivity and accuracy were 65% and 67%, respectively. Although
preoperative diagnosis of carcinoma of the papilla of Vater is useful for making therapeutic decisions, the diagnostic value
of the endoscopic appearance was superior to endoscopic biopsy in this series.
Presented at the 2003 American Hepato-Pancreato-Biliary Association Congress, Miami, Florida, February 27-March 3, 2003.
Supported by FADA-CAPES/PROP 200J (M.L.D.). 相似文献