首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   8262篇
  免费   342篇
  国内免费   375篇
耳鼻咽喉   13篇
儿科学   402篇
妇产科学   12篇
基础医学   196篇
口腔科学   12篇
临床医学   1074篇
内科学   972篇
皮肤病学   10篇
神经病学   4篇
特种医学   458篇
外科学   3107篇
综合类   1483篇
预防医学   317篇
药学   625篇
  6篇
中国医学   110篇
肿瘤学   178篇
  2023年   59篇
  2022年   185篇
  2021年   222篇
  2020年   183篇
  2019年   171篇
  2018年   191篇
  2017年   166篇
  2016年   268篇
  2015年   244篇
  2014年   574篇
  2013年   514篇
  2012年   541篇
  2011年   618篇
  2010年   542篇
  2009年   543篇
  2008年   510篇
  2007年   507篇
  2006年   511篇
  2005年   388篇
  2004年   308篇
  2003年   261篇
  2002年   231篇
  2001年   175篇
  2000年   142篇
  1999年   105篇
  1998年   104篇
  1997年   75篇
  1996年   63篇
  1995年   65篇
  1994年   51篇
  1993年   36篇
  1992年   33篇
  1991年   28篇
  1990年   49篇
  1989年   24篇
  1988年   46篇
  1987年   27篇
  1986年   19篇
  1985年   25篇
  1984年   22篇
  1983年   11篇
  1982年   25篇
  1981年   22篇
  1980年   14篇
  1979年   18篇
  1978年   13篇
  1977年   11篇
  1976年   14篇
  1975年   7篇
  1974年   6篇
排序方式: 共有8979条查询结果,搜索用时 15 毫秒
11.
Biliary stent causing colovaginal fistula: case report.   总被引:2,自引:0,他引:2  
OBJECTIVES: Perforation of the bowel during placement of a biliary stent is a known complication of this procedure. We report the endoluminal loss of a biliary stent during routine stent extraction that ultimately led to a chronic colovaginal fistula. This case emphasizes the need for evaluation of fecal passage of stents in patients with a known dislodged prosthesis. CASE REPORT: A 65-year-old white female underwent biliary stent placement for an episode of choledocholithiasis. The stent was lost in the duodenum during routine extraction. The patient was managed expectantly. She denied ever passing this stent via the rectum and began to develop symptoms of colovaginal fistula. Evaluation found a retained biliary stent in the sigmoid colon and a fistula into the vagina. The patient underwent elective low anterior resection and colovaginal fistula repair. DISCUSSION: Reports exist of migration of stents that lead to acute colonic perforation and the need for emergent surgery. For this reason, it has been suggested that dropped or migrated stents be purposefully retrieved. However, if the option of expectant observation is used, it is important to clearly document the fecal passage of these stents and be prepared to retrieve these objects if they have a prolonged bowel transit time.  相似文献   
12.
苄丙酮香豆素对实验性大鼠肾草酸钙结石形成的影响   总被引:1,自引:0,他引:1  
目的:探讨Vit.K拮抗剂苄丙酮香豆素(商品名华法令)对大鼠肾草酸钙结石形成的影响。方法:采用乙二醇饮水和氯化铵灌胃作成石剂,30只Wistar大鼠随机分为对照组(A组)、成石组(B组)、华法令组(C组)。饲养4周后,检测大鼠肾组织钙含量和草酸钙晶体形成、24h尿钙、尿草酸含量及血生化指标。结果:成石组和华法令组肾组织中钙、镁含量,24h尿草酸及尿钙、镁排泄量差异无显著性意义;镜下观察发现:华法令组大鼠肾脏草酸钙结晶形成多于成石组,但组间比较差异无显著性意义。结论:苄丙酮香豆素对大鼠肾草酸钙结石的形成无显著影响。  相似文献   
13.
Background Cold ischemia time and the presence of postoperative hepatic arterial thrombosis have been associated with biliary complications (BC) after liver transplantation. An ABO-incompatible blood group has also been suggested as a factor for predisposal towards BC. However, the influence of Rh nonidentity has not been studied previously. Materials Three hundred fifty six liver transplants were performed from 1995 to 2000 at our hospital. BC incidence and risk factors were studied in 345 patients. Results Seventy patients (20%) presented BC after liver transplantation. Bile leakage (24/45%) and stenotic anastomosis (21/30%) were the most frequent complications. Presence of BC in Rh-nonidentical graft–host cases (23/76, 30%) was higher than in Rh-identical grafts (47/269, 17%) (P = 0.01). BC was also more frequent in grafts with arterial thrombosis (9/25, 36% vs 60/319, 19%; P = 0.03) and grafts with cold ischemia time longer than 430 min (26/174, 15% vs 44/171, 26%; P = 0.01). Multivariate logistic regression confirmed that Rh graft–host nonidentical blood groups [RR = 2(1.1–3.6); P = 0.02], arterial thrombosis [RR = 2.6(1.1–6.4); P = 0.02] and cold ischemia time longer than 430 min [RR = 1.8(1–3.2); P = 0.02] were risk factors for presenting BC. Conclusion Liver transplantation using Rh graft–host nonidentical blood groups leads to a greater incidence of BC.  相似文献   
14.
肝移植术后并发胆道狭窄和胆泥淤积影像诊断及介入治疗   总被引:1,自引:0,他引:1  
目的:评价肝移植术后胆道狭窄和胆泥淤积影像诊断及介入治疗的价值。方法:对39例肝移植术后并发胆道狭窄和胆泥淤积的影像诊断及介入治疗进行回顾性分析。结果:超声、T型管胆道造影、CT和MRI检查诊断胆道狭窄伴胆泥形成39例,38例介入治疗后胆道梗阻症状明显缓解;1例介入治疗后胆道梗阻症状未明显改善,后行外科胆管修补术。结论:T型管胆道造影或直接经皮胆道造影对肝移植术后胆道狭窄和胆泥淤积诊断特异性及敏感性最高,放射介入和内镜介入技术对其均发挥重要的治疗作用。  相似文献   
15.
输尿管上段结石的微创手术治疗   总被引:12,自引:0,他引:12  
目的:探讨输尿管上段结石的治疗方法。方法:回顾性分析输尿管镜下气压弹道碎石(URSL),后腹腔镜输尿管切开取石(RLU)、经皮肾穿刺取石(PCNL)治疗输尿管上段结石患者的临床资料。其中URSL组25例,RLU组20例。PCNL组9例。结果:URSL组碎石成功18例;7例不成功,其中3例改为开放手术,1例改为后腹腔镜取石。2例行ESWL术,1例仅留置双J管。术后1个月拔管后自行排出。2例并发输尿管穿孔。RLU组取石成功18例,2例滑入肾内,经配合输尿管镜和腹腔镜直视下经皮肾穿刺取石成功,术后15例有伤口漏尿。PCNL组成功9例,无并发症。结论:USRL创伤小。术后恢复快。是治疗输尿管上段结石的较为满意的治疗方法。PCNL创伤小,取石成功率高,在结石靠近肾盂、儿童输尿管上段结石并同侧肾结石和结石以下输尿管狭窄时应优先考虑。但技术难度较大。RLU可作为URSL不成功后的辅助治疗方法。  相似文献   
16.
The incidence of stonestreet formation after extracorporeal shock wave lithotripsy (ESWL) rises with increasing stone burden. However, stonestreet after ESWL is often experienced even in stones smaller than 20 mm. To examine whether the non-contrast helical computed tomography (CT) data could predict stonestreet formation in these stones, 53 radiopaque stones of 5-20 mm treated with ESWL were evaluated. Maximal dimension was measured on plain radiograph. From an attenuation value histogram graphed from the CT data, total stone volume and mean attenuation value were calculated. Seven stonestreets longer than 25 mm developed. There was no significant difference in maximal dimension and total stone volume between stones that did and stones that did not develop stonestreet. Mean attenuation value was the sole significant predictive factor. Application of mean attenuation value with cut-off level of 650 HU would anticipate stonestreet formation with a sensitivity of 85.7% and a specificity of 71.7%. The estimated risk of stonestreet formation is high in the treatment of stones with higher mean attenuation value.  相似文献   
17.
目的比较钬激光输尿管硬镜碎石与经皮肾取石术治疗嵌顿性输尿管上段结石的疗效。方法106例单侧伴有肾积水的嵌顿性输尿管上段结石,48例采用URL治疗(URL组),58例采用PCNL治疗(PCNL组),统计分析2组的结石清除率及手术并发症。结果术后1 d结石清除率URL组25.0%(12/48)显著低于PCNL组98.3%(57/58)(χ^2=62.065,P=0.000);术后3个月结石清除率URL组77.1%(37/48)显著低于PCNL组100%(58/58)(χ^2=14.831,P=0.000);术后高热(T〉38.5℃)率URL组8.3%(4/48)与PCNL组6.9%(4/58)无统计学差异(χ^2=0.000,P=1.000)。结论对于嵌顿性输尿管上段结石,在有条件且技术成熟的医院PCNL可作为治疗的首选方法。  相似文献   
18.
本文报道1988年6月~11月,单独应用上海交通大学电力工程系研制的JT—ESWL—Ⅱ型体外震波碎石机,治疗尿路结石506例,其中肾结石304例(双侧12例)输尿管结石199例(双侧5例),膀胱结石3例。冲击能量15~40焦耳,每次治疗冲击波次数为400~2800次。本组无开放手术、无肾脏丧失、无死亡。效果满意者96.44%。其并发症主要有血尿、结石串。作者认为单用ESWL治疗小于3Cm的尿路结石安全可靠、无严重并发症。文中对单用体外震波碎石(ESWL)治疗尿路结石病例选择,如何减少并发症,提高治疗效果进行了讨论。  相似文献   
19.
刘胜利  陈峰 《江苏医药》1994,20(8):414-416
对我院14年来2322例直接胆管造影所发现的27例AJPBD进行研究,27例中胆总管囊肿8例,胆石症9例,慢性胰腺炎4例,胆管炎3例,胆囊癌2例,胰体癌1例。临床表现为上腹痛(92.6%),黄疸(70.4%),发热(48.1%)或Charcot三联症(44.4%)。发病年龄3~60岁(36.9士17.8)。共同管长15~44mm(20.2士5.9)。据胆、胰管汇合形式作者将AJPBD分为三型。值得注意的是本组3例复杂型患病年龄均<15岁。本组以胆、肠内引流手术效果满意。AJPBD与胆、胰疾病发生、发展密切相关,作者建议用“共同管综合征”来表述这一复杂病理现象。  相似文献   
20.
Background: One hundred eighty-one patients were submitted to laparoscopic common bile duct exploration. Methods: A transcystic approach was used in 147 patients, choledochotomy in 14, and both in 20. The indications to perform a choledochotomy included stones larger than 20 mm, stones proximal to the cystic duct entrance, and cases in which the transcystic duct approach proved impossible or unsuccessful. Results: The common bile duct was drained by a T-tube in four patients, by laparoscopic sphincterotomy in one, by laparoscopic choledochoduodenostomy in one, and by a 10 Fr endoprosthesis in 28. The stent placement was technically feasible in all patients but one. The biliary drainage was adequate. Mean hospital stay was 2.1 days. Complication was limited to one umbilical infection and one self-limited biliary leak. Conclusions: The procedure proved to be technically simple, safe, and efficient, and resulted in a low morbidity rate and short hospital stay. Received: 29 March 1996/Accepted: 12 June 1996  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号