急性心肌梗死PTCA及支架植入术后的康复护理

近年来，随着介入心脏病学的迅速发展，经皮冠状动脉腔内血管成形术（Percutaneous transluminal coronary angioplasty，PTCA）及冠状动脉支架植入术已成为治疗冠心病的重要方法之一。国内外在急性心肌梗死PTCA及支架植入术后患者的早期康复医疗方面已有较多研究，并在实践中证明，进行早期康复治疗能延长患者寿命及降低病死率。本院对58例此类患者进行早期康复活动观察，观察介入患者的最佳康复时间和指标，现将结果报道如下。     

Pediatric intracranial aneurysms——clinical characteristics and therapeutic strategies

Objective To assess the radiological characteristics and therapeutic strategies of intracranial aneurysms in children. Methods From our dedicated neurovascular databank of patients, we reviewed 23 consecutive children who had 24 intracranial aneurysms. There were 14 boys and 9 girls with a mean age of 9.09 years ( range 1 - 14 years ). Results Intracranial aneurysms in children ≤ 14 years constituted 1.3% of all intracranial aneurysms. Internal Carotid artery (ICA) and middle cerebral artery (MCA) were the most frequent sites for aneurysms. About 58.3% of the aneurysms were complex, including dissecting, pseudoaneurysm, giant and fusiform aneurysm. 1/3 of all aneurysms were located in posterior circulation. Only 1 case had multiple aneurysms in this case series. Almost half of all cases presented with subarachnoid hemorrhage and others presented with mass effect. 14 cases underwent endovascular treatment. 4 patients received microsurgical therapy. 5 cases did not receive microsurgical or endovascular therapy, 2 of them whose aneurysms spontaneously thrombosed during follow up. One boy with left vertebral artery giant aneurysm died after endovascular therapy owing to gradual thrombosis in basilar artery. Another child had poor outcome because of rerupture of aneurysm before operation. Whereas the majority had a favorable outcome. Conclusions Intracranial aneurysms in children had many clinical and radiological characteristics different from those in adults : ( 1 ) remarkable male predominance; ( 2 ) ICA and MCA were the most common sites for aneurysms; (3) high incidence of large, traumatic, infectious, dissecting and fusiform aneurysms. (4)For pediatric intracranial aneurysms, both microsurgical approaches and endovascular treatment were effective. Endovaacular therapy was the best choice for complex aneurysms.     

腹腔镜辅助下的腹主动脉瘤手术与传统手术的对比

腹主动脉瘤传统手术采用开腹人工血管置换，手术创伤大，术后患者恢复慢。随着腹腔镜在腹部外科应用的进展，传统腹主动脉瘤手术已经可以被腹腔镜辅助下完成人工血管置换所替代。此外，腹主动脉瘤腔内隔绝术部分并发症也能用腹腔镜辅助方式得到解决，现就该技术的操作、效果以及与传统手术的比较作一综述。     

卡托普利在临床应用中的不良反应

血管紧张素转换酶抑制剂（ACE1）近年来已广泛应用于临床，特别在心衰和高血压病的治疗上占据着其它药物无法替代的重要地位，近年来各种制剂不断问世并投入使用，但仍以卡托普利的应用最为广泛。随着临床使用的日益广泛，其不良反应的报告也日渐增多，现将卡托普利（CTP）在临床应用中发生的不良反应综述如下：     

血管内皮生长因子受体-2在膀胱癌组织中的表达及其重要意义

血管内皮细胞生长因子（VEGF）在维持肿瘤微脉管系统中发挥了重要作用，针对其进行抗新生血管的治疗已成为肿瘤治疗的新靶点。VEGF受体（VEGFR）特别是VEGFR2，在上皮性肿瘤细胞中的表达异常，使VEGF以自分泌或旁分泌方式刺激肿瘤细胞生长并发生转移。     

MRI联合磁共振血管成像诊断盆腔静脉瘀血综合征20例分析

1949年，Tayor首次将一种慢性盆腔疼痛综合征定义为盆腔静脉瘀血综合征。该综合征是由于盆腔静脉曲张、瘀血引起的一种妇科疾病，主要见于经产、育龄妇女。慢性盆腔疼痛足无规律的盆腔疼痛持续至少6个月，在妇产科患者中比较常见，占妇产科门诊就诊患者的10％-40％。约50％的盆腔静脉瘀血综合征患者存在慢性盆腔疼痛。但由于其临床表现复杂，缺乏特异性体征，常常被临床医师误诊或漏诊。本研究应用MRI平扫联合磁共振血管成像（magnetic resonance angiography，MRA）技术，探讨盆腔静脉瘀血综合征的MRI表现，为临床诊断提供准确、客观的依据。     

电视胸腔镜手术30例麻醉处理

电视胸腔镜（VATS）创伤小、恢复快，使用日渐增多。我院从2004年12月-2005年6月共进行了30例电视胸腔镜手术，取得了满意的效果，现将麻醉处理报告如下。     

神经病、神经外科和精神病学杂志

严重脑损伤后17年的社会心理调整;由琥珀酸脱氢酶（SDHA）黄素蛋白（Fp）亚单位突变所致Leigh综合征;动脉瘤性蛛网膜下腔出血早期循环中的内皮细胞激活标记物水平：与脑缺血事件和预后的关系;CSF前列腺素E2水平与认知功能下降和阿尔茨海默病存活率的关系；变异型克罗伊茨费尔特-雅各布病患者的CSF磷酸-tau蛋白浓度升高：诊断和病理学意义。