人工髋关节置换术后脂肪栓塞综合征的观察与护理

笔者报道人工髋关节置换术后脂肪栓塞综合征的护理措施认为重视氧饱和度及动脉血氧分压监测，注意观察中枢神经系统症状和呼吸系统症状，及时发现并纠止低氧血症，对不同的病人制定不同护理方案，严密观察病情，及时掌握病情变化：是护理的关键。     

激光辅助臀部脂肪抽吸

在臀部脂肪抽吸术中和术后辅助应用激光，是目前外科医师提高疗效和促进恢复的方法之一。     

[Ca^2＋]i change in hippocampal neurons influenced by preconditioning of etomidate fat emulsion following cerebral ischemia in rats

BACKGROUND: It is known that intravenous anesthetic etomidate fat emulsion has cerebral protection. Now many scholars focus on the research of its cerebral protection from molecular biology, but the mechanism of cerebral protection is still fully unclear. OBJECTIVE: To observe the influence of etomidate fat emulsion on the [Ca2+]i in hippocampal neurons during the transient cerebral ischemia injury in rats. DESIGN: Randomized controlled observation. SETTING: Weifang Medical College. MATERIALS: This study was carried out in the functional laboratory of Weifang Medical College between October 2005 and March 2006. Twenty-four male healthy Wistar rats, aged 3 to 4 months, were involved. Etomidate fat emulsion was provided by the limited company of En-hua Medical Bloc in Jiangsu Province (code of H20020511) and the other agents and materials were provided by Laboratory Center of Weifang Medical College. METHODS: The 24 Wistar rats were randomized into 3 groups: sham-operation group, model group and etomidate preconditioning group, with 8 rats in each. Rat models of transient cerebral ischemia injury were made by the ligation of bilateral carotid arteries combined with descending blood pressure in the latter two groups. Before ischemia (ligation of bilateral common carotid artery), rats in the etomidate preconditioning group were intraperitoneally injected with 12 mg/kg etomidate fat emulsion and then persistently intraperitoneally injected with etomidate fat emulsion at 1.0 mg/kg per minute. Rats in the model group were not administrated. Rats in the sham-operation group were only performed bilateral common carotid artery isolation. When rats were modeled, their brain tissues were quickly taken out and detected. MAIN OUTCOME MEASURES: Change of the fluorescence pixel value of the [Ca2+]i in each group by the laser scanning confocal microscope. RESULTS: Twenty-four rats were involved in the final analysis. Fluorescence pixel value in the sham-operation group was in the low level. Fluorescence pixel value in the model group was significantly higher than that in the sham-operation group (P < 0.01). Fluorescence pixel value in the etomidate preconditioning group was significantly lower than that in the model group (P < 0.01). CONCLUSION: The protection of etomidate fat emulsion to the transient cerebral ischemic injury in rats is associated with the inhibition to the increase of [Ca2+]i to some extent.     

饮食忌讳何需多

在科学家们对食物的长期研究中,曾经得到过这样或那样的错误结论,随后在深入的研究下又得到了有益的结论,但过去的错误观点已经在人们心中留下了深刻的印象,很有必要加以澄清,为这些无辜的食物正名,减少过多的饮食忌讳。为脂肪正名。吃太多的脂肪会引起肥胖症及其他有关疾病,有人就忌吃肥肉,怕吃动物油。其实饮食中数量充足的脂肪对于健康是必不可少的,除为满足能量之外,为满足对必需脂肪酸和脂溶性维生素的需求,都必须摄入足够的脂肪,尤其是处于能量平衡状态经常活动的成年人,如果摄入的必需脂肪酸和其他营养素等是足够的,则总消耗能量的35…     

心房充血分数评价高血压患者左室舒张功能的临床研究

目的探讨心房充血分数(AFF)在评价高血压患者左室舒张功能方面的临床应用价值。方法应用声学定量技术(AQ)对40名高血压患者及40名正常人的AAF值,快充血率峰值(PRFR)进行测定,并兼测了二尖瓣口E峰峰值速度与A峰峰值速度比(EV/AV)。结果高血压患者的AFF值明显高于正常人(P<0·001);而PRFR、EV/AV值明显低于正常人(P<0·001~P<0·05)。且所有受试者的AFF值与EV/AV值、PRFR值分别呈负相关(r=-0·51;r=-0·61)。结论AFF能够客观的反映高血压患者的左室舒张功能变化,对鉴别左室舒张功能异常有一定的诊断意义。     

降脂益肝冲剂治疗非酒精性脂肪性肝炎的实验研究

<正>动物实验证实,降脂益肝冲剂能够显著降低酒精加高脂饮食致脂肪肝大鼠血中丙氨酸转氨酶(ALT)、甘油三酯(TG),总胆固醇(TC)的含量,有效地逆转肝脏的脂质沉积状态,使肿     

肥胖与PPARγ及脂肪因子的研究进展

肥胖，即脂肪细胞数量的过度增加和体积的过度增大，并以体脂的形式储存过多摄入的能量，它是糖尿病、冠心病、高血压、高脂血症等许多严重疾病的共同危险因素。肥胖的发生除与不良生活习惯有关外，遗传因素和胰岛素抵抗是导致肥胖的最主要原因。过氧化物酶体增殖物激活受体（PPARγ）是脂肪细胞基因表达和胰岛素细胞间信号传递的主要调节者，参与脂肪细胞分化和脂代谢调节，与肥胖密切相关。因此，涉及脂肪细胞的过度增殖和分化而造成生成过多脂肪细胞的分子机制，以及脂肪组织分泌的多种细胞因子在机体能量、糖、脂代谢和免疫反应等方面所发挥的调节作用，一直是肥胖和糖尿病研究领域十分关注的问题。     

重度烧伤病人高比例脂肪乳剂静脉营养的应用

我们对１９９４年１月至１９９５年１２月入院的重度烧伤病人应用高比例脂肪（占总热量６０％）乳剂静脉营养１３例（高脂组），与脂肪占总热量３０％的低脂组１９例和不含脂肪乳剂静脉营养的２３例对照组进行了比较，结果发现高脂组丙氨酸转氨酶（ＡＬＴ）次数异常率比对...     

脂肪乳剂与淋巴细胞膜流动性

本文采用荧光偏振法测定淋巴细胞膜流动性,观察脂肪乳剂的作用,试图探讨脂肪乳剂与免疫细胞相互作用的机制。 材料和方法 一、研究分三部份 1.体外研究,从10例健康成年人外周静脉血分离淋巴细胞,分别与浓度为0,10mg/ml,20mg/ml的脂肪乳剂孵育60分钟,测细胞膜流动性。2.单次剂量研究,8例健康成年人静脉输入     

特发性椎管内硬膜外脂肪增多症：四例报告及文献复习

特发性椎管内硬膜外脂肪增多症——四例报告及文献复习鱼博浪张明王泽忠杨广夫椎管内硬膜外脂肪增多症是指脂肪组织在椎管内硬膜外间隙过度沉积。临床少见，常由于柯兴综合征或其他疾病长期大量使用糖皮质激素所致。发生于非柯兴综合征且无糖皮质激素服用史者，则称为特发...