原发性阴道癌的放射治疗

原发性阴道癌的治疗方法有单纯放射治疗、手术或手术加放疗、放疗加化疗综合治疗等。治疗方法的选择主要取决于病变部位，病灶大小、期别、各单位医疗条件、医生的经验。原位癌可局部切除或单纯腔内放疗，Ⅰ期和少数Ⅱ期早期可行手术治疗或单纯放疗，Ⅱ期至Ⅳ期行单纯放射治疗或同时性进行放射治疗和化疗。     

力达霉素对神经胶质瘤细胞血管生成拟态的抑制及对细胞凋亡的影响

Objective To evaluate the in vitro effects of lidamycin upon vasculogenic mimicry and apoptosis induction in glioma cells. Methods Tube formation assay was performed to estimate the inhibitory effects of lidamycin upon vasculogenic mimicry in C6 and U87 glioma cells. The vasculogenic mimicry of glioma cells was photographed and enumerated. Annexin V-FITC/PI was used for determination of glioma cell apoptosis with flow cytometry. Results Vasculogenic mimicry assay indicated that 0. 1 nmol/L, 0. 5 nmol/L and 1 nmol/L lidamycin showed significant inhibition of vasculogenic mimicry in C6 and U87 cells. Comparing with C6 control group (14. 7 ± 1.2), 0. 1 nmol/L (12. 7 ± 0. 6), 0. 5 nmol/L (9. 0 ± 1.7) and 1 nmol/L (4. 7 ± 0. 6) lidamycin inhibited vasculogenic mimicry in C6 cells with statistical significances (P = 0. 013, P = 0. 005 and P = 0. 0002 respectively). Comparing with U87 control group (14.7±1.2), the vasculogenic mimicry of 0.1 nmol/L (10.0±2.0), 0.5 nmol/L (8.3±1.5) and 1 nmol/L lidamycin (4. 3±0. 6) treated U87 cells showed statistical significances (P =0. 025, P =0. 005 and P =0. 0009 respectively). The apoptotic ratios of same dosages lidamycin treated C6 cells and U87 cells showed a similar tendency as vaaculogenic mimicry inhibition (P < 0. 001). Lidamycin was more potent than neocarzinostatin in vasculogenic mimicry inhibition and apoptosis induction of C6 cells and U87 cells. Conclusion Lidamycin can inhibit vasculogenic mimicry and promote apotosis of glioma cells. Thus it is a promising drug in glioma treatment. Further researches on the therapeutic efficacy of enediyne antibiotics in glioma are needed.     

阴道冲洗加微波照射结合局部放药治疗霉菌性阴道炎

目的探讨碳酸氢钠阴道冲洗加双唑泰阴道泡腾片阴道放药结合微波照射治疗霉菌性阴道炎的效果。方法将144例患者随机分2组各72例,治疗组采用阴道冲洗加微波然后放药治疗3 d,每日1次;对照组采用4%碳酸氢钠每晚阴道冲洗及制霉菌素2片每晚阴道放药1次。结果2组治疗效果经统计学处理具有显著性差异(P均<0.01)。结论治疗组治疗霉菌性阴道炎具有高效、安全、快速的特点。     

阴道窥灯对筛查宫颈早期病变的作用

为比较阴道窥灯检查与巴氏涂片、阴道镜检查对筛查早期子宫颈癌的作用,我院对136例妇女联合使用这3种方法检查和必要的活组织检查。     

小剂量阿克拉霉素治疗骨髓增生异常综合征3例

骨髓增生异常综合征(MDS)中RAEB及RAEB-T易向急性白血病转化,治疗上比较困难,我们用小剂量阿克拉霉素(ACR)治疗3例,效果满意,报告如下。     

在使用米非司酮终止早孕中阴道B超检测的应用

本文分析147例早孕妇女应用米非司酮终止早孕后的阴道B超检测结果,根据B超声象图的屏幕显示可分为四组:①宫腔内可见继续发育或停育变形的胎囊。②宫腔内仅见血液流动,未见胎囊。③内膜厚度≥10mm,伴有或不伴有回声增强或不匀。④内膜厚度<10mm,回声均匀或轻度不匀。根据本文结果,建议第1、2组应选择刮宫处理,第3组结合胎囊排出与否及出血量的多少再决定是否需要刮宫,第4组一般不需刮宫。     

妇科阴道流血的鉴别及护理对策

目的探讨有关阴道异常流血的鉴别及有关护理的问题.方法在护理工作中通过对妇科异常阴道流血的原因进行分析鉴别,并采取相应的护理措施.结果总结出针对性护理方面的异同点.结论对提高护士的护理诊断能力,加强工作的计划性和预见性,及时做好急救准备有着重要的意义.