Mirror-image dental fusion and discordance in monozygotic twins

A pair of monozygotic twins had similar but not identical dental anomalies. One twin had fusion of deciduous mandibular lateral incisor and canine on the left, with normal dentition on the right; the co-twin had right mandibular incisor/canine fusion, with aplasia of the lateral incisor on the left. These findings are discussed in the context of the related phenomena of situs inversus, mirror-imaging in twins, and gradients of severity of anomalies in the four copies of the mandibular developmental dental field. © 1994 Wiley-Liss, Inc.     

Osteogenesis imperfecta lethal in infancy: Case report and scanning electron microscopic studies of the deciduous teeth

Radiologic evaluation of the skeleton and scanning electron microscopic studies of the teeth were performed on an infant boy with a lethal osteogenesis imperfecta (OI) syndrome who died at 10 mo of pneumonia. The skeletal findings included ribs that were focally expanded by fracture calluses, flat vertebral bodies, and wide limb bones. On fractured tooth surfaces, the enamel and dentin were normal as was the dentin calcification front. Although microscopic abnormalities have been noted in teeth from previously reported infants with lethal OI, a few studies also report infants with normal teeth. These differences in dental findings may indicate heterogeneity in OI lethal in infancy. Results of our study indicate that, until the primary biochemical defects in the OI syndromes are elucidated, examination of teeth from other infants with lethal OI and detailed evaluation of other clinical and skeletal features will aid in delineating heterogeneity and variation in expression in lethal OI.     

Comparison of a traditional paracetamol medication and a new paracetamol/paracetamol-methionine ester combination

Summary The SUR 2647 combination is a sachet formulation containing free paracetamol and its N-acetyl-methionate ester (SUR 2647). In a randomized, single-blind, between-patient study the onset of analgesia, duration and efficacy of the SUR 2647 combination vs paracetamol was investigated in outpatients after oral surgery. One group (n=27) received sachets of SUR 2647 combination 2 b.i.d. (equivalent to 2 g paracetamol ×2) on the day of operation, and one sachet b.i.d. (equivalent to 1 g paracetamol ×2) for the following two days. The other group (n=26) received paracetamol tablets 2 q.i.d. on the day of operation (1 g×4) and one tablet q.i.d. (0.5 g×4) for the following two days. Several objective and subjective assessments, including pain score on a visual analogue scale, were recorded for comparison of the postoperative courses. Median onset of analgesia for both groups was 0.5 h. The duration after SUR 2647 combination was 5.5 h as compared to 2.5 h for paracetamol. Mean pain scores showed that the SUR 2647 combination regime reduced pain significantly more than the paracetamol regime from 0.5 to 3.0 h after initiation of medication. The mean pain scores did not show a significant difference during the remaining observation period. Mild to moderate drowsiness was reported in both treatment groups, but it was more common in subjects given SUR 2647 combination.     

"Fatigue on rest" and associated symptoms (headache, vertigo, blurred vision, nausea, tension and irritability) due to locally asymptomatic, unerupted, impacted teeth.

"Fatigue on Rest", headache, vertigo and the feeling of loss of balance, blurred vision, nausea, tension and irritability, were found to be prevalent amongst patients who had locally asymptomatic, unerupted impacted teeth. A comparative pressure sign was developed, which, when positive, confirmed the relationship between the impacted teeth and the medical symptoms. Removal of the impactions resulted in the alleviation of the symptoms. Stress and psychogenic factors are considered as trigger mechanisms, rather than as basic causes of the symptoms.     

应用Opalescence脱色方法治疗色素牙的疗效观察(附112例临床分析)

目的 :研究 Opalescence脱色方法对色素牙脱色的疗效。方法 :将 Opalescence脱色剂涂于个别托模唇、颊侧内 ,病人每晚睡前刷牙后擦干牙面 ,戴上托模 ,晨起摘下冲洗干净 ,每天 1次 ,疗程一般为 2周 ,视疗效及患者反应增减用药时间。结果 :1 1 2例患者脱色治疗后氟斑牙的显效率( 80 .8%)高于四环素牙的显效率 ( 66.7%)。有 2 3例病人疗效不甚满意。结论 :应用 Opalescence脱色治疗活髓色素牙效果明显 ,脱色后牙体呈自然色泽 ,透明感好 ,特别适用于年龄较轻、无牙体缺损的氟斑牙及四环素牙的脱色。     

人乳牙牙髓干细胞的体外培养观察

目的:体外分离、培养人乳牙牙髓干细胞。方法:采用酶消化法将人乳牙牙髓分离培养,以获得人乳牙牙髓干细胞。有限稀释法分离纯化,测定细胞克隆形成率,细胞计数法测生长曲线,细胞爬片行HE染色、碱性磷酸酶染色、抗波形蛋白(vimentin)免疫组化染色。结果:通过有限稀释法获得了克隆形成率为11～24个/103,细胞群体倍增时间为39.84h,HE染色细胞形态为梭形、细胞体小、胞核大的干细胞。且碱性磷酸酶染色阳性,抗波形蛋白(vimentin)免疫组化染色阳性。结论:人乳牙牙髓中可分离培养出牙髓干细胞。     

心理暗示干预在老年人牙拔除术中的应用

目的：探讨心理暗示干预在老年人牙拔除术中的应用价值。方法：将老年人拔牙患者118例随机分为心理暗示组及对照组各59例。心理暗示组在拔牙术前采用心理暗示干预的方法,对照组未给予任何暗示,按照沉稳型、张乱型及混合型三个等级统计数据,进行对比研究。结果：心理暗示组的沉稳型率显著高于对照组（P〈0.01）,张乱型率显著低于对照组（P〉0.05）。结论：心理暗示干预应用于老年人牙拔除术时,可明显降低患者的畏惧程度,缩短手术时间,确保手术的顺利进行,有一定的应用价值。     

犬恒牙牙根发育过程中牙髓炎症对细胞凋亡的影响

目的：探讨牙髓炎症对牙根发育过程中细胞凋亡的影响。方法：建立犬年轻恒牙实验性牙髓炎模型,采用原位末端标记技术（TUNEL）观测牙根发育过程中犬恒牙牙髓炎症对各组织中凋亡细胞分布的影响。结果：与炎症区相邻的牙髓组织中细胞凋亡数量增多,参与牙根发育的各种功能细胞（成牙本质细胞、成牙骨质细胞、上皮根鞘细胞、成骨细胞和牙周膜细胞）也出现非生理性的凋亡。结论：牙根发育过程中牙髓炎症状态下细胞凋亡一方面参与牙髓组织自身防御,另一方面则干扰了牙根的正常发育。     

Rare non‐syndromic bilateral maxillary and mandibular permanent canine agenesis

Oligodontia or absence of teeth such as the Canines is rare and is often accompanied with several other missing teeth. This condition may also be accompanied with morphological and growth related changes in the teeth and the maxillofacial complex. Complete agenesis of the permanent canines in the maxilla and the mandible is extremely rare and occurs in association with syndromic oligodontia. Non‐syndromic absence of canines however, is extremely rare and has only been reported twice. Studies have shown that the incidence of missing canines is more in females. This report describes a sporadic case of congenital absence of maxillary and mandibular bilateral canines. The patient reported to the clinic with a chief complaint of crowding and wanted alignment. On intra‐oral examination it was observed that the patient had all permanent canines missing with no prior history of extractions, crowding in both the arches and class I molars on both sides. With no other symptoms fixed orthodontic therapy was planned for the patient with premolars substituted for the canines.     

情景式引导联合针对性健康教育在永久性起搏器植入术后患者功能锻炼中的应用观察

目的:分析永久性起搏器植入手术患者采用情景式引导以及针对性健康教育对患者功能锻炼的影响.方法:选择在某院进行永久性起搏器植入手术治疗的74例患者为研究对象,其治疗时间均在2018年11月～2019年11月之间,采取随机数字排列表法将其分为常规组和实验组各37例.常规组患者实施基础健康教育指导,实验组患者实施情景式引导以...