“Vanishing Bone Disease” in Maxillofacial Region: A Review and Our Experience

Vanishing bone disease (VBD) is a rare disease of unknown etiology which is characterised by progressive replacement of bony framework by proliferation of endothelial lined lymphatic vessels. It has been given numerous names like massive osteolysis, Gorham’s disease, phantom bone disease, and progressive osteolysis. It has no age, sex or race predilection. It may involve single or multiple bones and spread of the disease does not respect the relevant joint as boundary. The first report of the disease was published around two decades back but the mysterious nature of its etiology and ideal management strategy has still not been completely unfolded. The disease may functionally or aesthetically effect the patient and also has the potential to be life threatening. The first case of VBD in maxillofacial region was reported by Romer in 1924, Handbuch der speziellen pathologischen Anatomie and histology, Springer, Berlin. Since then, there have been few case reports of the same in maxillofacial region. We present a review of cases of VBD in maxillofacial region reported in literature along with our experience of a case.     

关节镜辅助下克氏针、钢丝张力带治疗髁间棘骨折的疗效分析

目的:分析克氏针、钢丝张力带治疗髁间棘骨折的临床疗效。方法:对我科2011年-2017年收治的58例Ⅱ型及以上的髁间棘骨折采用关节镜辅助下克氏针、钢丝张力带的方法进行固定,术后定期复查评估膝关节稳定性、活动度及骨折愈合情况,并采用Lysholm评分系统对膝关节功能进行评估。结果:58例患者均获得随访,术后6周复查膝关节屈伸0°-120。及以上,术后3个月复查X线提示骨折愈合良好,抽屉实验、Lachman实验阴性,末次随访Lysholm评分(94.6±1.1)分,较术前(73.6±2.6)分显著提高,差异有统计学意义(P<0.05)。结论:关节镜辅助下克氏针、钢丝张力带治疗髁间棘骨折固定牢靠,方法简单实用,经济低廉,膝关节功能恢复满意。     

Resorption of deproteinized bovine bone mineral in a porcine calvaria augmentation model

Objectives: The original aim of the study was to determine the osteoconductive capacity of deproteinized bovine bone mineral (DBBM) of different particle sizes underneath acrylic hemispheres in vivo. However, the model failed and allowed us to report on the resorption of DBBM. Material and methods: Acrylic hemispheres were filled with and without a DBBM at a small particle size of 125–250 μm and at the regular particle size of 250–1000 μm. The hemispheres were positioned on the calvaria of eight minipigs. Histological and histomorphometric analysis was performed after 12 weeks. Results: We found that the acrylic hemispheres were displaced and a dense fibrous capsule sequestered the augmented area. Histology showed severe resorption activity and the presence of multinucleated cells on the surface of DBBM particles in areas adjacent to the fibrous capsule. Histomorphometric analysis revealed that only less than half of the originally augmented area, which was approximately 30 mm², remained after 12 weeks. The amount of residual DBBM (median 0.9 and 3.49 mm²) and bone (median 7.22 and 7.51 mm²) in the augmented area was similar in the small and the regular particle size group. Conclusion: The model represents a pathologic situation of excess resorption of DBBM and bone in an augmented area. The underlying cellular mechanisms remain to be uncovered. To cite this article:
Busenlechner D, Tangl S, Arnhart C, Redl H, Schuh C, Watzek G, Gruber R. Resorption of deproteinized bovine bone mineral in a porcine calvaria augmentation model.
Clin. Oral Impl. Res. 23 , 2012; 95–99.
doi: 10.1111/j.1600‐0501.2011.02198.x     

A Comparative Evaluation of Static and Functional Methods for Recording Centric Relation and Condylar Guidance: A Clinical Study

To evaluate and compare the centric relation and horizontal condylar guidance using interocclusal wax and extra oral Gothic arch methods and subjective evaluation of dentures thus fabricated. Centric relation and horizontal condylar guidance was recorded by using interocclusal wax and gothic arch tracing in 28 completely edentulous patients. These records were transferred to the articulator and difference in both values was recorded. After that patients were divided in two groups according to the centric relation and horizontal condylar guidance recording method used to achieve balanced occlusion. Response of the dentures was subjectively evaluated using “Woelfel subjective evaluation criteria”. Centric relation recorded by both the methods did coincide in 7.14 % of patients. Centric relation recorded by interocclusal wax was posterior to Gothic centric relation in 21.43 % of patients, and anterior to Gothic centric relation in 71.42 % patients. Gothic arch tracings gave higher mean guidance values on both the sides as compared to protrusive wax record in all the subjects, although the difference was statistically insignificant (P > 0.05). Subjective evaluation showed statistical insignificance for all the parameters in both groups. Gothic arch method records the centric relation at a more posterior position than the Static method, but it does not make any difference in clinical performance of the complete denture. Horizontal condylar guidance angle was approximately similar by both the methods.