全文获取类型
收费全文 | 8780篇 |
免费 | 628篇 |
国内免费 | 183篇 |
专业分类
耳鼻咽喉 | 38篇 |
儿科学 | 111篇 |
妇产科学 | 31篇 |
基础医学 | 719篇 |
口腔科学 | 832篇 |
临床医学 | 982篇 |
内科学 | 819篇 |
皮肤病学 | 58篇 |
神经病学 | 27篇 |
特种医学 | 121篇 |
外科学 | 284篇 |
综合类 | 1250篇 |
现状与发展 | 1篇 |
预防医学 | 2714篇 |
眼科学 | 74篇 |
药学 | 1179篇 |
7篇 | |
中国医学 | 251篇 |
肿瘤学 | 93篇 |
出版年
2024年 | 20篇 |
2023年 | 130篇 |
2022年 | 369篇 |
2021年 | 469篇 |
2020年 | 291篇 |
2019年 | 274篇 |
2018年 | 209篇 |
2017年 | 221篇 |
2016年 | 428篇 |
2015年 | 490篇 |
2014年 | 673篇 |
2013年 | 744篇 |
2012年 | 665篇 |
2011年 | 726篇 |
2010年 | 503篇 |
2009年 | 394篇 |
2008年 | 337篇 |
2007年 | 404篇 |
2006年 | 306篇 |
2005年 | 268篇 |
2004年 | 250篇 |
2003年 | 202篇 |
2002年 | 145篇 |
2001年 | 141篇 |
2000年 | 121篇 |
1999年 | 94篇 |
1998年 | 79篇 |
1997年 | 75篇 |
1996年 | 64篇 |
1995年 | 56篇 |
1994年 | 61篇 |
1993年 | 71篇 |
1992年 | 53篇 |
1991年 | 35篇 |
1990年 | 41篇 |
1989年 | 24篇 |
1988年 | 20篇 |
1987年 | 26篇 |
1986年 | 6篇 |
1985年 | 10篇 |
1984年 | 14篇 |
1983年 | 10篇 |
1982年 | 9篇 |
1981年 | 9篇 |
1980年 | 7篇 |
1979年 | 12篇 |
1978年 | 8篇 |
1977年 | 8篇 |
1976年 | 10篇 |
1974年 | 4篇 |
排序方式: 共有9591条查询结果,搜索用时 0 毫秒
31.
Anselme Millogo Ahmed Loukil Coralie LOllivier Diakourga Arthur Djibougou Sylvain Godreuil Michel Drancourt 《Emerging infectious diseases》2021,27(6):1758
Mycobacterium leprae was detected by optical microscopy, fluorescent in situ hybridization, and molecular detection in feces collected for the diagnosis of Entamoeba coli enteritis in a leprosy patient in Burkina Faso. This observation raises questions about the role of fecal excretion of M. leprae in the natural history and diagnosis of leprosy. 相似文献
32.
全国细菌耐药监测网 《中国感染控制杂志》2021,20(1):53-60
目的探讨全国尿标本分离细菌菌种分布及耐药变迁。方法按照全国细菌耐药监测网(CARSS)技术方案,应用WHONET5.6软件对2014—2019年所有CARSS成员单位上报的尿标本分离细菌及药敏结果数据进行分析。结果男性患者尿标本分离细菌居前5位者分别为大肠埃希菌(33.1%~34.6%)、粪肠球菌(9.2%~10.2%)、肺炎克雷伯菌(9.0%~9.4%)、屎肠球菌(7.8%~10.2%)和铜绿假单胞菌(5.6%~6.9%),女性患者尿标本分离细菌居前5位者分别为大肠埃希菌(57.0%~57.4%)、肺炎克雷伯菌(7.5%~8.3%)、屎肠球菌(6.8%~8.7%)、粪肠球菌(5.5%~6.0%)和奇异变形杆菌(3.3%~3.5%)。男性和女性患者尿标本分离粪肠球菌对氨苄西林和呋喃妥因耐药率分别<12%和7%,对万古霉素耐药率<3%;屎肠球菌对氨苄西林、左氧氟沙星耐药率均为90%左右,对万古霉素耐药率<4%。大肠埃希菌对头孢曲松耐药率>47%,对头孢哌酮/舒巴坦、哌拉西林/他唑巴坦、呋喃妥因耐药率≤8%,对于β-内酰胺类耐药率男性比女性高,其中头孢曲松的耐药率高12个百分点左右。男性患者分离肺炎克雷伯菌对头孢曲松耐药率为58%左右,女性患者耐药率为45%左右。男性和女性患者尿标本分离铜绿假单胞菌对头孢哌酮/舒巴坦和哌拉西林/他唑巴坦的耐药率均<14%,对碳青霉烯类耐药率为15%左右。鲍曼不动杆菌对头孢哌酮/舒巴坦和米诺环素耐药率分别<27%和22%,对碳青霉烯类耐药率,男性为31.7%~47.7%,女性为26.5%~41.2%。结论尿标本分离细菌在不同性别构成上有所不同,且部分肠杆菌目细菌耐药率不同性别间也有一定差异,不同年度间部分细菌的耐药率也有一定变化。尿标本分离细菌的耐药监测,可为尿路感染抗菌药物合理应用提供参考数据。 相似文献
33.
目的分析脊柱术后医院感染患者病原菌分布特征及中性粒细胞64(CD64)和中性粒细胞百分比(NEU%)表达情况。方法选取2017年6月-2019年6月天津市天津医院收治的脊柱术后医院感染患者51例为感染组,并选取同期于医院就诊的脊柱术后未发生感染患者51例为未感染组。分析感染组患者病原菌情况,检测患者NEU和CD64水平;ROC曲线分析CD64和NEU%指标水平预测感染的诊断价值。结果 51例感染患者共培养分离病原菌78株,其中革兰阴性菌42株(53.85%)、革兰阳性菌33株(42.31%)、真菌3株(3.85%),以铜绿假单胞菌及金黄色葡萄球菌为主。术后7 d,感染组体温、WBC、中性粒细胞计数、CRP、ESR分别为(38.47±0.52)℃、(8.34±2.17)×109/L、(5.98±1.94)×109/L、(54.52±19.93)mg/L、(51.74±21.88)mm/h均高于非感染组(P<0.05)。术后7 d,感染组CD64、NEU%分别为(8.87±2.13)%、(84.93±13.39)高于非感染组(P<0.05)。CD64指数与NEU%水平诊断ROC曲线下面积分别为0.922、0.826。结论脊柱术后医院感染以革兰阴性菌为主,CD64及NEU%水平有助于脊柱术后医院感染的早期诊断。 相似文献
34.
Connie A. Haley Patricia Macias Supriya Jasuja Betsy A. Jones Marie-Claire Rowlinson Roshni Jaimon Pennelyn Onderko Elaine Darnall Maria E. Gomez Charles Peloquin David Ashkin Neela D. Goswami 《Emerging infectious diseases》2021,27(1):332
The US Food and Drug Administration approved a 6-month regimen of pretomanid, bedaquiline, and linezolid for extensively drug-resistant or multidrug-intolerant tuberculosis after a trial in South Africa demonstrated 90% effectiveness 6 months posttreatment. We report on a patient who completed the regimen using a lower linezolid dose. 相似文献
35.
Julie Bennett Jane Zhang William Leung Susan Jack Jane Oliver Rachel Webb Nigel Wilson Dianne Sika-Paotonu Matire Harwood Michael G. Baker 《Emerging infectious diseases》2021,27(1):36
We describe trends in acute rheumatic fever (ARF), rheumatic heart disease (RHD), and RHD deaths among population groups in New Zealand. We analyzed initial primary ARF and RHD hospitalizations during 2000–2018 and RHD mortality rates during 2000–2016. We found elevated rates of initial ARF hospitalizations for persons of Māori (adjusted rate ratio [aRR] 11.8, 95% CI 10.0–14.0) and Pacific Islander (aRR 23.6, 95% CI 19.9–27.9) ethnicity compared with persons of European/other ethnicity. We also noted higher rates of initial RHD hospitalization for Māori (aRR 3.2, 95% CI 2.9–3.5) and Pacific Islander (aRR 4.6, 95% CI 4.2–5.1) groups and RHD deaths among these groups (Māori aRR 12.3, 95% CI 10.3–14.6, and Pacific Islanders aRR 11.2, 95% CI 9.1–13.8). Rates also were higher in socioeconomically disadvantaged neighborhoods. To curb high rates of ARF and RHD, New Zealand must address increasing social and ethnic inequalities. 相似文献
36.
Amyn A. Malik Neel R. Gandhi Timothy L. Lash Lisa M. Cranmer Saad B. Omer Junaid F. Ahmed Sara Siddiqui Farhana Amanullah Aamir J. Khan Salmaan Keshavjee Hamidah Hussain Mercedes C. Becerra 《Emerging infectious diseases》2021,27(3):805
In Karachi, Pakistan, a South Asian megacity with a high prevalence of tuberculosis (TB) and low HIV prevalence, we assessed the effectiveness of fluoroquinolone-based preventive therapy for drug-resistant (DR) TB exposure. During February 2016–March 2017, high-risk household contacts of DR TB patients began a 6-month course of preventive therapy with a fluoroquinolone-based, 2-drug regimen. We assessed effectiveness in this cohort by comparing the rate and risk for TB disease over 2 years to the rates and risks reported in the literature. Of 172 participants, TB occurred in 2 persons over 336 person-years of observation. TB disease incidence rate observed in the cohort was 6.0/1,000 person-years. The incidence rate ratio ranged from 0.29 (95% CI 0.04–1.3) to 0.50 (95% CI 0.06–2.8), with a pooled estimate of 0.35 (95% CI 0.14–0.87). Overall, fluoroquinolone-based preventive therapy for DR TB exposure reduced risk for TB disease by 65%. 相似文献
37.
Marni LaFleur Kim E. Reuter Michael B. Hall Hoby H. Rasoanaivo Stuart McKernan Paulo Ranaivomanana Anita Michel Marie Sylvianne Rabodoarivelo Zamin Iqbal Niaina Rakotosamimanana Simon Grandjean Lapierre 《Emerging infectious diseases》2021,27(3):977
We diagnosed tuberculosis in an illegally wild-captured pet ring-tailed lemur manifesting lethargy, anorexia, and cervical lymphadenopathy. Whole-genome sequencing confirmed the Mycobacterium tuberculosis isolate belonged to lineage 3 and harbored streptomycin resistance. We recommend reverse zoonosis prevention and determination of whether lemurs are able to maintain M. tuberculosis infection. 相似文献
38.
Katrin Gaardbo Kuhn Anne Kathrine Hvass Annette Hartvig Christiansen Steen Ethelberg Susan Alice Cowan 《Emerging infectious diseases》2021,27(4):1133
Campylobacteriosis is a disease of worldwide importance, but aspects of its transmission dynamics, particularly risk factors, are still poorly understood. We used data from a matched case-control study of 4,269 men who have sex with men (MSM) and 26,215 controls, combined with national surveillance data on Campylobacter spp., Salmonella spp., and Shigella spp., to calculate matched odds ratios (mORs) for infection among MSM and controls. MSM had higher odds of Campylobacter (mOR 14, 95% CI 10–21) and Shigella (mOR 74, 95% CI 27–203) infections, but not Salmonella (mOR 0.2, 95% CI 0–13), and were less likely than controls to have acquired Campylobacter infection abroad (χ2 = 21; p<0.001). Our results confirm that sexual contact is a risk factor for campylobacteriosis and also suggest explanations for unique features of Campylobacter epidemiology. These findings provide a baseline for updating infection risk guidelines to the general population. 相似文献
39.
Seema Irfan Mohammad Zeeshan Salima Rattani Joveria Farooqi Sadia Shakoor Rumina Hasan Afia Zafar 《Emerging infectious diseases》2021,27(3):936
We evaluated Salmonella enterica serotype Typhi strains isolated from all body sites in Pakistan during 2013–2018. Despite an increase in overall number of localized, extensively drug-resistant Salmonella Typhi in organ infections during 2018, there was no increase in the proportion of such isolates in comparison with non–extensively drug-resistant isolates. 相似文献
40.
Jos María Robaina-Bordn Cristina Carranza-Rodríguez Michele Hernndez-Cabrera Margarita Bolaos-Rivero Elena Pisos-lamo Nieves Jan-Snchez Araceli Hernndez-Betancor Laura Surez-Hormiga Jos Luis Prez-Arellano 《Emerging infectious diseases》2021,27(2):570
To document the epidemiology, clinical features, and outcomes of murine typhus patients in the Canary Islands (Spain), we analyzed data that were retrospectively collected for 16 years for 221 patients. Murine typhus in the Canary Islands is characterized by a high rate of complications (31.6%), mainly liver, lung, kidney or central nervous system involvement. 相似文献