KYP型Q开关倍频Nd：YAG激光治疗太田痣72例的护理体会

目的：探讨KYP型Q开关倍频Nd：YAG激光治疗太田痣护理体会。方法我科于2008年10月~2014年8月应用KYP型Q开关倍频Nd：YAG激光治疗太田痣患者72例,回顾性分析通过患者的积极配合和治疗过程中精心的护理。结果取得显著疗效。结论手术前后的护理,及时的沟通解决,缩短了恢复时间,减少了并发症,大大增加了患者的满意度。     

Q开关和长脉宽1064nm Nd:YAG激光真皮胶原重建疗效的比较性研究

目的:本研究拟定量地比较Q开关和长脉宽1064 nm掺钕:钇-铝石榴石(neodymium-yttrium-aluminum garnet,Nd:YAG)激光诱导真皮胶原重建的疗效。方法:应用Q开关和长脉宽1064 nm Nd:YAG激光分别对36只雌性昆明小鼠左侧后背皮肤进行连续4次治疗,每次间隔1周,右侧相应的部位作为自身对照。分别于第1次治疗后1h、1天、7天、21天、30天和60天对小鼠皮肤行活组织取材。应用免疫组化方法分别对皮肤组织样品中真皮I、III型胶原进行检测,染色结果应用Motic医学数字图像分析系统进行定量分析。结果:与正常对照组相比,Q开关1064 nm Nd:YAG激光治疗后7天、21天、30天和60天,真皮I型胶原及III型胶原水平明显增高(均P0.01)。长脉宽1064 nm Nd:YAG激光治疗后21天、30天和60天,真皮I型胶原水平明显增高(均P0.01);激光治疗后7天、21天、30天和60天,真皮III型胶原水平明显增高(分别为P0.01、P0.05、P0.01、P0.01)。两组激光的比较:激光治疗后7天、21天和30天,Q开关1064nm Nd:YAG激光治疗组真皮I型胶原水平较长脉宽1064nm Nd:YAG激光治疗组明显增高(均P0.01),而激光治疗后60天明显降低(P0.05);激光治疗后7天和21天,Q开关1064nm Nd:YAG激光治疗组较长脉宽1064nm Nd:YAG激光治疗组真皮III型胶原水平明显增高(分别为P0.05、P0.01)。结论:Q开关和长脉宽1064nm Nd:YAG激光均可引起真皮胶原重建,但二者的作用效果不尽相同。     

Comparison of Q-switched Nd:YAG laser alone versus its combination with ultrapulse CO2 laser for the treatment of black tattoo

Background: Q-switched lasers are conventionally used for the treatment of black tattoo. However, they require multiple sittings, and the response may be slow due to competing epidermal pigment in dark skin. Objective: To compare the efficacy of Q-switched Nd:YAG laser alone with its combination with ultrapulse CO₂ for the removal of black tattoo. Materials and methods: Sixty patients with black tattoo were randomized into two groups viz., group A and group B. Group A was treated with QS Nd:YAG laser (1064 nm) alone, and group B received combination of ablative ultrapulse CO₂ followed by fixed-dose QS Nd:YAG laser (1064 nm), at 6-week interval for a maximum of 6 sittings. After each sitting, 3 independent physicians noted percentage of improvement that was evaluated using visual analogue scale (VAS) and grading system for tattoo ink lightening (TIL). Results: Combination laser (group B) showed statistically significant improvement in mean VAS score in the last 2 noted visits as compared to 1st session (p < 0.007, p < 0.001) and TIL mean score in last three noted visits as compared to 1st session (p < 0.008, p < 0.020, and p < 0.004). There was no statistically significant difference in the side effect profile of both the groups. Conclusion: For refractory professional tattoos, combination of ultrapulse CO₂ laser and QS Nd:YAG laser is superior to QS Nd:YAG laser alone.     

Q开关1064 nm Nd:YAG激光治疗黄褐斑所致点状色素减退:2年随访研究

目的:了解大光斑低能量模式Q开关1064 nm激光治疗黄褐斑后所致点状色素减退恢复情况。方法:对大光斑低能量模式Q开关1064 nm Nd:YAG激光治疗5次以上的180例黄褐斑患者随访2年。结果:15例出现点状色素减退(8.33%),2年后1例痊愈,2例有改善,13例无变化。结论:大光斑低能量Q开关1064 nm激光治疗黄褐斑所致的点状色素减退斑可持续2年以上。     

Transluminal Nd: YAG laser embolysis for branch retinal artery occlusion: Case report

Rationale:Central retinal artery occlusion and branch retinal artery occlusion (BRAO) result in partial or complete retinal ischemia and sudden loss of vision; to date there is no effective therapy for central retinal artery occlusion and BRAO. Transluminal Nd:YAG laser embolysis (TYE) could represent a therapeutic approach for retinal vascular occlusive diseases.Patient concerns:We report 2 cases with BRAO, 1 with inferor-temporal and 1 with superor hemiretinal BRAO. All the patients complained of a history of sudden blurry vision and impaired visual field and had a visible embolus within the intravascular, all of them treated with TYE, the laser applications being delivered directly to the embolus.Diagnosis:The diagnosis was based on the results from color retinography, optical coherence tomography and visual field testing. Fundus fluorescein angiography clearly indicated the location of retinal artery occlusion.Interventions:The patients’ symptoms could not be relieved after dilating the blood vessels in the eye, lowering intraocular pressure, massaging the eyeball, and inhaling oxygen. Informed consent was obtained from the patient for TYE and the patients were referred for this procedure.Outcomes:Upon the successful competition of the TYE procedure the embolus was removed completely, restoring the blood flow in the intraocular vessels and improving significantly the patients’ visual acuity.Lessons:World-wide experience with TYE is still limited, but the technique seems feasible for the treatment of RAO caused by visible emboli on the optic disc surface and the posterior pole of the fundus oculi.     

不同表面处理对Bio-HPP与PMMA粘结强度影响的研究

目的:采用喷砂、Nd:YAG激光对聚醚醚酮生物复合材料(Bio-HPP)进行表面处理,观察其对Bio-HPP与聚甲基丙烯酸甲酯(PMMA)间粘接效果的影响。方法:68个Bio-HPP试件随机分成4组:CG、SA0.05、SA0.35、LA;表面处理后,扫描电镜观察,测试表面粗糙度;试件与PMMA粘接后一半浸泡蒸馏水24 h,另一半冷热循环5000次,万能试验机测试剪切强度。结果:扫描电镜观察,LA,SA较CG表面粗糙;表面粗糙度:CGNd:YAG激光处理可以改变Bio-HPP表面形貌,提高Bio-HPP的粘接性能,适当提高喷砂压强有利于Bio-HPP与PMMA粘接的稳定。     

宫腔镜下Nd:YAG激光治疗子宫内疾病78例分析

目的 :评价宫腔镜对子宫内疾病的诊断价值和采用Nd :YAG激光治疗子宫内疾病的效果。方法 :对 78例子宫内疾病 (包括子宫内粘连、子宫粘膜下肌瘤、子宫纵隔、子宫粘膜息肉、宫颈息肉及宫颈管囊肿 )采用宫腔镜进行诊断 ,并用Nd :YAG激光进行治疗。结果 :宫腔镜诊断子宫内疾病的准确率高于超声诊断及放射诊断。采用Nd :YAG激光治疗的一次性成功率为 97.43 %。手术时间为 2 0 5 5分钟 ,平均 3 5 .7± 18.5分钟。无明显并发症。术后 1 3个月随访 2例病人有残留的粘连带及纵隔组织而进行二次手术。其余患者均恢复正常。 8例患者 (有生育要求者 )在一年内妊娠。结论 :对于子宫内疾病宫腔镜有较高的临床价值 ,采用Nd :YAG激光治疗具有更简便、安全、疗效确切等优点 ,具有广泛的应用前景