富血小板血浆联合骨髓间充质干细胞不同 配比浓度对兔软骨缺损的影响

目的: 研究富血小板血浆(PRP)与骨髓间充质干细胞(BMSCs)不同的配比浓度对兔软骨缺损的治疗效果。方法: 随机将60只新西兰兔随机分为模型对照组、PRP组(3%)、BMSCs组(1×10⁶/mL)、不同配比浓度的PRP+BMSCs联合组(1:5,2:5,3:5)。建立兔软骨损伤模型,术后第2周靶侧肌肉注射不同配比浓度的PRP与BMSCs,每周1次,连续给药4周。采用Masson's三色染色法,观察关节软骨缺损情况;采用Pineada法进行关节软骨组织学半定量计分,并通过观察患兔术膝切口,了解术后愈合情况。结果: 与模型对照组比较,不同配比浓度的PRP与BMSCs联合组中的关节软骨半定量分值均减少(P<0.05)。不同配比浓度的PRP与BMSCs联合组中,关节软骨半定量分值随PRP浓度的增加而减少,关节软骨半定量分值与PRP值呈现线性关系,其中PRP与BMSCs配比浓度为3:5的效果最为明显,差异有显著性意义(P<0.05)。结论: PRP,BMSCs在一定程度上可促进骨组织恢复;关节软骨缺损恢复程度与PRP浓度表现出一定的量效关系。     

Commentary—Marasmus in a Newly Rich Urbanized Society

To assess the feasibility of fortifying flour with folic acid as a strategy to prevent neural tube defects in Malaysia, a country where the staple food is rice, we used 24-hour recall to study all cereal flour intake in women of reproductive age. Eighty-eight percent took at least a half portion of cereal flour and 85% took at least one whole portion. Vitamin supplements were taken by 36% but few knew whether the supplement contained folic acid. Cereal flour consumption is frequent and folic acid fortification of flour is feasible. Subgroups of the population not consuming flour need to be identified.     

牙种植修复牙列缺损185例远期效果临床观察

目的探讨牙种植修复对牙列缺损的远期效果。方法回顾性分析我院2005年6月-2007年6月接受牙种植修复治疗的185例（339枚）牙列缺损患者临床资料,分析植入后0．5、1、3、5年植入成功率及牙槽骨吸收和周围软组织情况。结果半年内成功336枚,成功率为99．1％;负载1、3、5年后,累积成功率分别为99．1％、97．6％、95．0％。结论对牙列缺损患者进行全面评价,选择合适的种植方法和时机,可取得良好的远期修复效果。     

Effects of chronic smoking on color vision in young subjects

AIM: To evaluate the effects of chronic smoking on color vision in young subjects. METHODS: This study included 91 smokers and 88 non-smokers (a total of 179 volunteers) without any ophthalmologic and systemical disorders. The subjects were between 18-40 years of age with a best corrected visual acuity (BCVA) of 20/20, normal anterior and posterior segment examinations and normal intraocular pressure. The color vision of the subjects were evaluated with Farnsworth-Munsell 100 Hue test (FMHT). The total error scores and axis calculation were performed for each subject and the results correlated. RESULTS: Mean age and the standard deviation was 28±5y in the smokers group, and 26.7±5.5y in the control group (P=0.101). Sex distribution was similar in the two groups (P=0.365). There was no significant correlation between age and FMHT total error scores (P=0.069). Median of FMHT total error scores of smokers and non-smokers were 65 and 50.50, respectively. FMHT total error scores was found significantly higher in smokers than non-smokers (P=0.004). There was no statisticaly significant difference between smoker and non-smoker groups with respect to axis ratio calculation (P=0.611). There was no significant correlation with FMHT total error scores with neither smoking duration nor number of cigarettes smoked per day (P=0.405, P=0.454, respectively). CONCLUSION: This study suggested that chronic smoking affects the color vision of young smokers but this may not be sector selective.     

Fallot四联症的MRI诊断

笔者分析了２１例经心血管造影和手术证实的Ｆａｌｌｏｔ四联症的ＭＲＩ，探讨ＭＲＩ在显示四联症病理解剖中的作用。提出了显示不同解剖结构应采用的扫描方法，认为ＭＲＩ可以较清晰地显示四联症的肺动脉狭窄、室间隔缺损、主动脉骑跨和右心室肥厚。与其他检查方法相比，ＭＲＩ的诊断能力等于或优于超声心动图；在确定室间隔缺损类型、大小，观察右心室肥厚及肺动脉闭锁时观察中央肺动脉方面优于心血管造影检查。     

Laparoscopic Surgery for Genuine Stress Incontinence

Laparoscopic Burch colposuspension has rapidly become one of the primary surgical treatment options for genuine stress incontinence. The procedure has been modified by some investigators because of technical difficulty with laparoscopic suturing, but should be identical to the conventional open Burch procedure. This article reviews the indications, operative technique, clinical results, complications and learning curve for laparoscopic retropubic surgical procedures.     

口内进路下颌角及咬肌肥大矫正术

为了避免面部留有切口疤痕,寻找出一种简单方便的回内进路手术方式。方法：口内进路、用skruber摆动锯截除肥大的下颌角,来复锯经日内补充截除骨断面下部骨突起及部分骨下绿,再用长柄骨磨头进一步磨改。结果：12例患者面形改善明显。结论：下颌角及咬肌肥大采用正颌外科技术经单纯的日内进路不需作辅加切口即能达到良好的手术效果。     

皮肤与骨骼复合缺损的修复

目的 探讨显微外科修复肢体骨与皮肤复合缺损的技术和效果。方法 39例肢体骨与皮肤复合缺损患者接受显微外科手术修复:游离移植背阔肌肌皮瓣,而后髂骨植骨4例,移植髂骨皮瓣7例,移植腓骨皮瓣6例,组合移植背阔肌肌皮瓣与游离腓骨20例,组合移植双侧背阔肌肌皮瓣与游离腓骨2例。结果 移植组织完全成活30例,9例移植的(肌)皮瓣远端皮肤发生局部浅表坏死,经换药后愈合。移植骨术后12～18周与宿主骨牢固连接。平均随访3年6个月,修复肢体均恢复有用功能。14例12岁以下儿童,修复后下肢生长正常,未发生肢体不等长现象。结论 严格手术指征,准确操作,酌情选择不同皮瓣与骨复合组织移植的显微外科修复是治疗骨与皮肤缺损的有效手段。