BackgroundThe aim of this systematic review was to determine whether secondary closure (SC) or primary closure (PC) is better at preventing postoperative complications after impacted mandibular third-molar extraction.Types of Studies ReviewedThe authors sought randomized controlled trials comparing the effects of PC and SC on pain, swelling, trismus, infection, and bleeding after impacted mandibular third-molar extraction. Screening, data extraction, and risk of bias assessments were conducted independently and in duplicate. The reviewers pooled results across studies using a random-effects meta-analysis and assessed the certainty of the evidence using the Grading of Recommendations Assessment, Development and Evaluation approach.ResultsThis review identified 785 unique citations and included 40 trials. Compared with PC, SC was found to have trivial benefits for pain at day 7 and trismus within 1 week (moderate certainty). The incidence of infection and bleeding did not differ importantly between techniques (moderate certainty). However, SC is probably associated with less swelling on day 1 (standardized mean difference, –0.98; 95% CI, –1.22 to –0.73; moderate certainty) and day 3 (standardized mean difference, –0.87; 95% CI, –1.16 to –0.59; moderate certainty). There was very low certainty evidence for pain on days 1 and 3 and low certainty evidence for swelling on day 7.Conclusions and Practical ImplicationsClinicians choosing between closure techniques should be aware that SC probably imparts an important benefit only for swelling at days 1 and 3. There seems to be a trivial difference between the techniques in other outcomes. 相似文献
Objectives: To consider the biologic behaviors of keratocystic odontogenic tumors (KCOTs) and
ameloblastomas and dentigerous cysts.
Methods: A 63-year-old Japanese man presented with swelling and discomfort in the left cheek during jaw movement. Examination revealed a multilocular lesion within the mandible extending from the left second premolar to the left mandibular ramus and coronoid process; the lesion contained a deviated impacted tooth. The tumor had expanded beyond the bone and was invading the masseter and medial pterygoid muscles. Marginal mandibulectomy with a free iliac bone graft was performed.
Results: No recurrence was observed during a 7-year follow-up.
Discussion: The histopathological diagnosis of the lesion showed it was a KCOT. These tumors usually grow within the bone, causing bone expansion. However, this tumor had expanded beyond the bone and invaded surrounding muscles. Thus, KCOTs can, in rare cases, manifest themselves as described here. Evaluating preoperative images and histopathological findings is important to determine the optimal treatment strategy. 相似文献
The authors updated a previously published systematic review to assess the effects of low-level laser therapy (LLLT) on reducing complications after the removal of impacted mandibular third molars.
Types of Studies Reviewed
The authors searched for randomized clinical trials in which the investigators evaluated the efficacy of LLLT compared with that of placebo or no treatment. Two reviewers independently screened studies, extracted data, and assessed risk of bias. The authors used random effects model meta-analysis and the Grading of Recommendations Assessment, Development and Evaluation approach to rate the certainty of evidence.
Results
The authors included 21 studies. There was low-certainty evidence that LLLT results in less pain at 2 days after surgery (mean difference [MD], ?1.42 on a 10 point scale; 95% confidence interval [CI], ?2.18 to ?0.67) and moderate certainty that it results in negligibly less pain at 7 days (MD, ?0.59; 95% CI, ?0.96 to ?0.22); moderate-certainty evidence that LLLT has a negligible benefit on reducing trismus at 2 days (MD, ?3.42 millimeters; 95% CI, ?5.34 to ?1.50) and at 7 days after surgery (MD, ?2.30 mm; 95% CI, ?3.96 to ?0.64); lastly, there was moderate-certainty evidence that LLLT results in less postoperative swelling at 2 days (standardized MD, ?0.82; 95% CI, ?1.28 to ?0.35) and low-certainty evidence that LLLT results in negligibly less postoperative swelling at 7 days after surgery (standardized MD, ?0.17; 95% CI, ?0.4 to 0.07). Low-quality evidence suggests that LLLT will not cause adverse effects.
Conclusions and Practical Implications
LLLT probably has negligible benefits but may not result in adverse events. Evidence does not support the use of LLLT in clinical practice to reduce complications after impacted mandibular third-molar surgical extractions. 相似文献