全文获取类型
收费全文 | 13792篇 |
免费 | 669篇 |
国内免费 | 154篇 |
专业分类
耳鼻咽喉 | 307篇 |
儿科学 | 72篇 |
妇产科学 | 51篇 |
基础医学 | 1105篇 |
口腔科学 | 4169篇 |
临床医学 | 745篇 |
内科学 | 345篇 |
皮肤病学 | 17篇 |
神经病学 | 970篇 |
特种医学 | 869篇 |
外科学 | 2949篇 |
综合类 | 1452篇 |
预防医学 | 265篇 |
眼科学 | 589篇 |
药学 | 509篇 |
7篇 | |
中国医学 | 75篇 |
肿瘤学 | 119篇 |
出版年
2024年 | 224篇 |
2023年 | 313篇 |
2022年 | 486篇 |
2021年 | 605篇 |
2020年 | 541篇 |
2019年 | 426篇 |
2018年 | 488篇 |
2017年 | 460篇 |
2016年 | 534篇 |
2015年 | 455篇 |
2014年 | 896篇 |
2013年 | 883篇 |
2012年 | 789篇 |
2011年 | 847篇 |
2010年 | 658篇 |
2009年 | 731篇 |
2008年 | 699篇 |
2007年 | 635篇 |
2006年 | 532篇 |
2005年 | 413篇 |
2004年 | 390篇 |
2003年 | 356篇 |
2002年 | 240篇 |
2001年 | 243篇 |
2000年 | 205篇 |
1999年 | 159篇 |
1998年 | 142篇 |
1997年 | 155篇 |
1996年 | 120篇 |
1995年 | 116篇 |
1994年 | 105篇 |
1993年 | 71篇 |
1992年 | 86篇 |
1991年 | 57篇 |
1990年 | 55篇 |
1989年 | 55篇 |
1988年 | 52篇 |
1987年 | 45篇 |
1986年 | 54篇 |
1985年 | 38篇 |
1984年 | 46篇 |
1983年 | 20篇 |
1982年 | 30篇 |
1981年 | 26篇 |
1980年 | 27篇 |
1979年 | 19篇 |
1978年 | 19篇 |
1976年 | 15篇 |
1974年 | 14篇 |
1973年 | 14篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
41.
目的 观察氯地滴眼液对家兔眼压及房角组织影响。方法 用60只家兔设实验和对照组,以含0.175%氯霉素和0.15%地塞米松的氯地跟液滴眼,每日4次,生理盐水对照。于1/2、1、2、3月测眼压后处死家兔以电镜观察房角组织变化。结果 眼压和房角组织结构与对照组无明显差异。结论 临床应用氯地眼液3月内是安全的。 相似文献
42.
P. W. Hanlo R. H. J. M. Gooskens J. A. J. Faber R. J. A. Peters A. A. M. Nijhuis W. P. Vandertop C. A. F. Tulleken J. Willemse 《Child's nervous system》1996,12(4):200-209
The treatment of choice in progressive hydrocephalus is drainage of cerebrospinal fluid in order to reduce elevated intracranial pressure (ICP). Defining the right moment for surgical intervention, however, in a hydrocephalic infant on the basis of clinical signs alone can be a difficult task. Clinical signs of raised ICP are known to be unreliable and sometimes even misleading. In the present study, the relationship between long-term anterior fontanelle pressure (AFP) measurements and clinical signs was investigated in 37 infants with hydrocephalus. The decision as to whether to operate or not was based on clinical signs alone; AFP values were not taken into account. There was an overall difference between the non-operated group and the preoperative measurements in the operated group, and also between the preoperative and the postoperative measurements in the latter, in regard to both AFP measurements and clinical signs. Almost all preoperative AFP values were increased. The direct correlation () between most individual clinical signs and AFP levels, however, was low (=0.15–0.41). The clinical sign tense fontanelle showed the best correlation with the AFP levels (=0.75). Furthermore, using logistic regression analysis, no combination of clinical signs could be found which reliably predicted the AFP. The relationship between the AFP pressure variables and clinical signs was also examined. The pathological A-waves occurred only in the presence of raised (baseline) AFP, a situation in which considerably more frequent B-waves were observed as well. It was concluded that clinical signs of raised ICP in infantile hydrocephalus are not very reliable and AFP monitoring can therefore provide valuable information on intracranial dynamics in patients with dubious neurological manifestations of progressive hydrocephalus. 相似文献
43.
In a follow-up study 27 patients were evaluated after anterior cruciate ligament (ACL-)reconstruction combined with high tibial osteotomy because of chronic rupture of the ACL, cartilaginous lesions of the medial compartment and varus malalignment. They were divided into two groups. In 14 patients (non-LAD group) ACL reconstruction was performed using the central third of the autologous patellar tendon modified according to Eriksson-Trillat. Thirteen patients (LAD group) underwent repair with the same technique, but a Kennedy ligament augmentation device (LAD) in hot dog technique and fixed over the top was added. The postoperative treatment was the same in both groups. All patients were examined according to IKDC criteria. KT-1000 arthrometer testing at maximum manual traction was performed. Although the mean follow-up interval was more than double in the non-LAD group (non-LAD: 127 months vs LAD: 58 months), the subjective and clinical results, IKDC evaluation and KT-1000 arthrometer testing results were similar, showing no statistically significant difference. Further, no complications due to the use of LAD occurred. In this study no evident functional or clinical advantage from the augmentation performed could be shown.Investigation performed at the Department of Orthopaedic and Trauma Surgery, University Hospital Basle, Switzerland. No benefits in any form have been received or will be received from a commercial party related directly or indirectly to the subject of this article. Funds were received in total or partial support of the research or clinical study presented in this article. The funding sources were SUVA Assurance, Lucerne, and the science fund of the University Hospital Basle 相似文献
44.
目的:探讨改良口外须颅颌固定治疗上颌骨骨折的临床效果。方法:对35例上颌骨Le FortⅡ、Ⅲ型骨折患者,先行闭合复位,恢复受伤前的咬合关系,再行改良口外须颅颌固定牵引3~4周。结果:35例Le FortⅡ、Ⅲ型骨折患者总有效率达94.2%。结论:改良口外须颅颌固定牵引治疗上颌骨骨折是一种简单易行、可靠的方法。 相似文献
45.
目的:探讨心理暗示干预在老年人牙拔除术中的应用价值。方法:将老年人拔牙患者118例随机分为心理暗示组及对照组各59例。心理暗示组在拔牙术前采用心理暗示干预的方法,对照组未给予任何暗示,按照沉稳型、张乱型及混合型三个等级统计数据,进行对比研究。结果:心理暗示组的沉稳型率显著高于对照组(P〈0.01),张乱型率显著低于对照组(P〉0.05)。结论:心理暗示干预应用于老年人牙拔除术时,可明显降低患者的畏惧程度,缩短手术时间,确保手术的顺利进行,有一定的应用价值。 相似文献
46.
犬恒牙牙根发育过程中牙髓炎症对细胞凋亡的影响 总被引:1,自引:0,他引:1
目的:探讨牙髓炎症对牙根发育过程中细胞凋亡的影响。方法:建立犬年轻恒牙实验性牙髓炎模型,采用原位末端标记技术(TUNEL)观测牙根发育过程中犬恒牙牙髓炎症对各组织中凋亡细胞分布的影响。结果:与炎症区相邻的牙髓组织中细胞凋亡数量增多,参与牙根发育的各种功能细胞(成牙本质细胞、成牙骨质细胞、上皮根鞘细胞、成骨细胞和牙周膜细胞)也出现非生理性的凋亡。结论:牙根发育过程中牙髓炎症状态下细胞凋亡一方面参与牙髓组织自身防御,另一方面则干扰了牙根的正常发育。 相似文献
47.
ObjectiveTo present the clinical characteristics of accumulated anterior cruciate ligament (ACL) damage among young male patients undergoing routine exercise, and to evaluate the related risk factors.MethodsA retrospective study involving ACL‐accumulated damage from June 2015 to December 2019 was conducted. Baseline characteristics, such as age, body mass index (BMI), training parameters, and clinical signs, were recorded. The results of the radiologic examinations and related standardized tests were obtained to evaluate the research outcomes. These results were compared using Student''s t‐test or Chi‐square test, and the impact of risk factors on the patient''s injury were analyzed.ResultsA total of 86 men with accumulated ACL damage were included in this study. Exercise pain (86 [100%]), synovitis (80 [93.0%]), and intra‐articular effusion (79 [91.9%]) were the most common clinical symptoms. Loosening of ligaments, decreased tension, mild hyperplasia, and intercondylar fossa effusion were observed using radiography, magnetic resonance imaging, and arthroscopy. Age, BMI, training intensity, length of training, and knee hyperextension were identified as risk factors for accumulated ACL damage.ConclusionThis study suggests that accumulated ACL damage has differentiated clinical symptoms, imaging features, and risk factors compared to common ACL injuries. 相似文献
48.
目的 应用头颅定位侧位片分析上颌发育不足患者在不同生长发育阶段进行前牵引治疗的临床效果。方法 选取2018年1月至2020年12月于上海交通大学附属第九人民医院口腔正畸科完成前牵引治疗的上颌发育不足患者36例,根据头颅定位侧位片颈椎骨龄分期(cervical vertebral maturation method,CVM),分为生长发育高峰前期组(CVMⅠ~Ⅱ期)7例、生长发育高峰期组(CVMⅢ~Ⅳ期)17例以及生长发育后期组(CVMⅤ~Ⅵ期)12例。各组患者治疗前后分别拍摄头颅定位侧位片,对其软硬组织相关指标进行测量分析。结果 骨性矢状向指标上牙槽座角(SNA角)、上颌突距(A-Np)、前鼻嵴点至垂直参考轴的距离(VRL-ANS)、上牙槽座点至垂直参考轴的距离(VRL-A)、有效上颌长度(Co-A)、上下牙槽座点交角(ANB角)、Wits值在3组治疗前后的差异均有统计学意义(P <0.05),其中治疗后生长发育高峰前期组A-Np改变值[(2.61±1.11)mm]与生长发育后期组[(1.00±0.82)mm]相比,差异有统计学意义(P=0.017);骨性垂直向指标腭平面倾斜角(... 相似文献
49.
膝腱反射检查对前交叉韧带断裂和重建后本体感觉功能的评价 总被引:1,自引:1,他引:0
目的探讨膝腱反射检查对前交叉韧带断裂和重建后本体感觉功能的评价和意义。方法对20例单纯前交叉韧带断裂,采用关节镜下自体四股半腱肌-股薄肌肌腱重建。常规方法检查膝腱反射,双极表面电极电刺激髌韧带并记录股内侧肌肌电图。观察前交叉韧带断裂和重建后膝腱反射和肌电图的客观改变,结合临床"打软腿"的主观症状,研究主、客观相互关系。结果3项指标手术前后两样本率比较,差异有统计学意义(PKJ=0.004,PEMG=0.022,PS=0.000);3项指标手术前后改变率之间两两比较,差异无统计学意义(PKJ-EMG=0.495,PKJ-S=0.476,PEMG-S=0.163)。结论提出"前交叉韧带-膝腱反射弧"的观点,将膝腱反射检查作为前交叉韧带断裂和重建后的常规查体,借此评价膝关节本体感觉功能,以指导本体感觉的康复锻炼。 相似文献
50.
目的:观察中药治疗慢性上颌窦炎的临床疗效。方法:治疗组40例用中药,对照组40例用克拉霉素口服,治疗3个月。结果:总有效率治疗组87.50%,对照组57.50%。两组比较有极显著性差异(P〈O.05)。结论:中药治疗慢性上颌窦炎疗效较好,无明显副作用。 相似文献