替硝唑碘仿糊剂乳牙根管治疗170例的临床观察

由于近年来耐药菌株增多，细菌性肺炎治疗难度增大。为选择一种有效抗生素以解决这一难题，我们在教学医院随机选取急性细菌性肺炎５０例，用利迈先（克拉霉素）进行治疗观察其疗效，并设对照组对比分析，旨在评价利迈先的临床价值。１临床资料病例来自１９９６年１２月～２００１年３月教学医院内科住院的病例中，选择入院时具备的条件是：经X线胸部透视或摄片有炎症性改变，外周血中性粒细胞升高，病史在３天以内；临床诊断：急性细菌性肺炎。选择符合上述条件者临床资料较完整９８例，随机抽取５０例为治疗组，４８例为对照组进行疗效分…     

灭滴灵复合药物空管疗法的实验研究及五年临床疗效观察

用灭滴灵复合药物对２４个狗单根牙实验性尖周炎进行空管药物疗法，并用另外２４个狗单根牙实验性尖周炎为两治疗对照组。对这４８个实验狗牙在实验后４５ｄ，９０ｄ和１８０ｄ对其尖周的组织学变化进行了显微镜观察。狗牙尖周炎细胞减少或消失，有明显胶元纤维修复，牙骨质和牙槽骨右明显新生组织沉积线，时间越长，效果越好。文中还对１６１人１８３个矛用灭滴灵复合药物空管疗法治疗的各类患牙经５年随访观察。获９１．８％的治愈率。     

医用低值材料采供管理的探讨

医疗消耗材料是医疗工作开展的基础，本文从医用低值消耗材料的计划制定、材料采购、库房库存结构、材料供应、成本核算等多方面探讨了如何对医疗消耗材料进行科学管理，这对医院的医疗发展和管理建设有着重要意义。     

基因活化材料的构建及在骨与软骨损伤中的应用

组织工程技术为关节软骨的再生带来希望，适当浓度的生长因子、合适的微环境无疑会利于这种技术的实施。近年来，生物可降解材料作为基因传送载体转染体细胞的研究正逐渐受到重视，可以利用生物材料的降解特性以及化学构成特点构建具有可控制性、安全性、靶向性的转染系统，通过靶细胞表达转移后的基因片段，可以在局部持续获得治疗性的生长因子。     

寰枢椎椎弓根钉固定治疗伸直型齿状突骨折合并寰枢关节半脱位

Objective To explore the clinical outcome of atlantoaxial pedicle screw instrument in treatment of extension-type odontoid fracture combined with aflantoaxial subluxation. Methods From December 2002 to December 2006, seven patients with extension-type odontoid fracture combined with at-lantoaxial subluxation were reduced and fixed with atlantoaxial pedicle screw instrument of Vertex system under general anesthesia. There were five males and two females, at mean age of 39.2 years (range 21-59 years). All odontoid fractures were fresh type Aderson Ⅱ. JOA scores of spinal core function was 8.6-14.9 (average 10.7) preoperatively. The X-ray examination, CT scanning and skull traction were performed in all patients preoperatively. Results There found no severe complications such as injuries of vertebral artery, nerve root and spinal cord postoperatively. All patients obtained complete reduction and healing of the fracture and dislocation. The mean off-bed time was four days (3-6 days) after opera-tion. A follow-up for 12-36 months (average 22 months) in all patients showed that the clinical symptom was improved significantly six months postoperatively and that all screws were in proper position verified by X-ray and CT scanning. All patients obtained solid bony union on radiographs, with no loosing or breakage of instrument. The postoperative JOA scores was 13.5-16.9 (average 15.8). Conclusions Allantoaxial pedicle screw fixation has advantages of intraoperative reduction, reliable fixation and high fusion rate and can be used as an effective method for extension-type odontoid fracture combined with at-lantoaxial subluxation.     

聚乳酸骨固定材料的研究

用聚乙烯醇(PVA)的二甲基亚砜(DMSO)溶液对水热反应法合成的超细羟基磷灰石(HAP)进行表面改性，用溶液分散复合法分别制备了HAP含量均为0．03g／mE的聚乳酸(PLLA)／HAP和PLIA／HAP-PVA复合物，并经过挤出成型得到φ=5mm的棒材。重点研究了热拉伸取向的拉伸规律及表面改性前后HAP粒子在PLLA基质中的分散情况。结果表明，经PVA改性的HAP粒子在PLLA基质中的分散要明显优于未经改性的HAP粒子。拉伸取向后PLLA／HAP-PVA复合材料的弯曲强度达262MPa。