全文获取类型
收费全文 | 17127篇 |
免费 | 1523篇 |
国内免费 | 362篇 |
专业分类
耳鼻咽喉 | 328篇 |
儿科学 | 609篇 |
妇产科学 | 44篇 |
基础医学 | 1695篇 |
口腔科学 | 100篇 |
临床医学 | 888篇 |
内科学 | 599篇 |
皮肤病学 | 31篇 |
神经病学 | 10065篇 |
特种医学 | 422篇 |
外科学 | 816篇 |
综合类 | 1515篇 |
现状与发展 | 1篇 |
预防医学 | 347篇 |
眼科学 | 196篇 |
药学 | 972篇 |
5篇 | |
中国医学 | 244篇 |
肿瘤学 | 135篇 |
出版年
2024年 | 41篇 |
2023年 | 375篇 |
2022年 | 276篇 |
2021年 | 508篇 |
2020年 | 666篇 |
2019年 | 636篇 |
2018年 | 564篇 |
2017年 | 573篇 |
2016年 | 611篇 |
2015年 | 577篇 |
2014年 | 975篇 |
2013年 | 1022篇 |
2012年 | 882篇 |
2011年 | 959篇 |
2010年 | 750篇 |
2009年 | 794篇 |
2008年 | 854篇 |
2007年 | 842篇 |
2006年 | 817篇 |
2005年 | 666篇 |
2004年 | 600篇 |
2003年 | 541篇 |
2002年 | 448篇 |
2001年 | 402篇 |
2000年 | 328篇 |
1999年 | 295篇 |
1998年 | 293篇 |
1997年 | 292篇 |
1996年 | 239篇 |
1995年 | 228篇 |
1994年 | 217篇 |
1993年 | 144篇 |
1992年 | 175篇 |
1991年 | 156篇 |
1990年 | 115篇 |
1989年 | 109篇 |
1988年 | 89篇 |
1987年 | 84篇 |
1986年 | 118篇 |
1985年 | 124篇 |
1984年 | 104篇 |
1983年 | 100篇 |
1982年 | 87篇 |
1981年 | 74篇 |
1980年 | 66篇 |
1979年 | 52篇 |
1978年 | 36篇 |
1977年 | 19篇 |
1976年 | 24篇 |
1974年 | 17篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
51.
Eun Yeon Joo Jee Hyun Kim Woo Suk Tae Sun Jung Han Seunghwan Kim Myoung-Hee Kim Hong Sik Byun Seung Bong Hong 《Journal of neuroimaging》2004,14(4):365-368
A patient with chronic cerebral paragonimiasis began to have new motor seizures of the right face manifested by clonic contractions that occurred several hundred times a day, consistent with simple partial status epilepticus. Ictal electroencephalogram discharges started from the left frontal region and then spread to the left hemisphere with left frontal maximum. But clinical seizures were limited to the right face. The frequent partial seizures were controlled by the intravenous infusion of phenytoin. Brain magnetic resonance imaging showed multiple conglomerated round nodules with encephalomalacia in the left temporal and occipital lobes. Applying the technique of ictal-interictal single-photo emission computed tomography subtraction, the authors were able to localize the focal ictal-hyperperfusion on left precentral cortex adjacent to the lesions that correspond to the anatomical distribution of left face motor area. 相似文献
52.
53.
D Guillaume T Grisar A V Delgado-Escueta M Bureau-Heeren J Laschet 《Journal of neuroscience research》1991,29(2):207-217
Partially purified (Na+,K+)-ATPase (E.C. 3.6.1.3.) was investigated in the epileptic cortex of audiogenic DBA/2 mice and in the primary and secondary foci of cats with acute or chronic freeze lesions. No differences in specific activities measured at 3 mM K+ were observed between epileptic and control cortex, except an increase of enzymic activities in the primary focus of acutely lesioned cats. The (Na+,K+)-ATPase catalytic subunits were resolved by SDS-gel electrophoresis and their phosphorylation levels were measured in presence of K+ ions and phenytoin. K+ was more effective in inducing maximal dephosphorylation of (Na+,K+)-ATPase in C57/BL, with identical affinity in the two strains. Phenytoin decreased the net phosphorylation level of (Na+,K+)-ATPase by about 50% in C57/BL mice, but only by 20% in DBA/2 mice. Both K+ and phenytoin dephosphorylating influences were decreased in primary and secondary foci of acutely lesioned cats. Those changes were limited to the alpha(-) subunit. In chronic cats, the dephosphorylating step of the (Na+,K+)-ATPase catalytic subunit recovered a normal affinity to K+, but its sensitivity to phenytoin remained decreased. Those differences in K+ and phenytoin influences on brain (Na+,K+)-ATPases between control and epileptic cortex might be responsible for the ictal transformation and seizure spread. In cats, the alteration of the alpha(-) isoform could mainly affect the glial cells. 相似文献
54.
视频脑电图诊断儿童癫痫128例 总被引:4,自引:1,他引:3
目的 分析视频脑电图(Video-EEG)在小儿癫痫诊断,分类中的应用价值及癫痫发作期的EEG特点。临床诊断的癫痫患儿128(男94,女34)例,1mo-14岁,平均年龄5.4岁,应用伟思VEEG1161B型视频脑电图仪,对患儿进行至少4-6h包括清醒与睡眠期的临床和EEG监测。监测中对各种状态及事件进行标记,结束后将EEG信号与临床录象资料同步回放并逐秒分析。结果 128例癫痫患儿中有54例(42.2%)进一步确定了癫痫综合征的诊断,其中儿童良性癫痫伴中央-颞区棘波25例,儿童失神癫痫3例,少年肌阵挛癫痫1例,额叶癫痫5例,West综合征13例,Lennox-Gastaut综合征7例,有49例(38.3%)可明确其发作类型,其中强直或(和)阵挛发作10例,部分性发作33例,肌阵挛发作5例,失张力发作1例,另外有25例(19.5)尚无法分类。结论 视频脑电图 是诊断癫痫及明确癫分类的可靠检查方法。 相似文献
55.
用微量马桑内酯注入Wistar大鼠左侧前肢运动皮质,造成急性局灶型癫痫。用光镜、电镜和体视学方法研究其运动皮质第V层结构的改变。结果显示:癫痫大鼠运动皮质灶区、灶旁区的神经细胞数和胶质细胞数均分别比对照大鼠灶区和灶旁区显著减少;灶区神经毡中突触性终末数,显著减少;突触性终末的面积分数明显减少,而树突的面积分数无变化;神经胶质突起的面积分数增加。 相似文献
56.
57.
本文报道100例原发全身性癫痫家系的遗传流行病学研究结果。先证者一级亲属患病率为6.86%,二级亲属为1.03%;分别是对照组一级亲属的13.83倍和2.08倍。原发全身性癫痫的遗传度为:一级亲属0.7521±0.0678,二级亲属0.3592±0.0746;加权平均0.5743±0.0502。说明遗传因素起重要作用。发病年龄影响因素分析表明:原发全身性癫痫有一定年龄依从性。EEG家系分析显示,该型癫痫一级亲属癫痫样放电明显高于对照组一级亲属,提示癫痫样放电的遗传倾向。 相似文献
58.
59.
60.
The sequence of rat hypothalamic pro-thyrotropin releasing hormone, deduced by sequencing of cDNA, in addition to 5 TRH progenitor genitor sequences contains leader, trailer and 4 intervening sequences separated by paired basic amino acid sequences. We have developed radioimmunoassays to synthetic peptides corresponding to portions of these cryptic proTRH sequences and have used these assays to identify and partially characterize proTRH peptides, distinct from TRH, in extracts of rat brain. Two of these peptides correspond closely in size to one intervening sequence and the car☐y-terminal sequence of proTRH. Three other peptides correspond to the intact amino-terminal leader sequence and two peptides formed by a further cleavage of the leader sequence at an internal paired basic amino acid sequence. 相似文献