Role of progesterone on the control of scent marking in Suncus murinus viridescens (Blyth)

The effect of castration and administration of progesterone in different doses on the specialized integumentary glands and scent marking behavior in male musk shrew, Suncus murinus viridescens were studied. Castration effected a considerable atrophy of the secretory epithelial tissues of the flank, oral lip and perineal glands with marked regression in their secretory output. Further, the scent marking frequencies were also reduced and attained a minimum level by the end of 4 weeks after castration. Progesterone administration in effective doses reactivated all these specialized integumentary glands and the scent marking frequency in male shrews within a period of three weeks.     

推拿结合膏摩治疗神经根型颈椎病疗效观察

目的观察推拿结合膏摩治疗神经根型颈椎病的临床疗效。方法将92例神经根型颈椎病患者随机分为3组：综合组32例采用推拿结合膏摩治疗,推拿组30例采用单纯推拿治疗,膏摩组30例采用单纯膏摩治疗。均治疗1个疗程（15次）。结果综合组的总有效率为87．50％,推拿组为80．00％,膏摩组为56．67％;前两组的总有效率高于后者（P〈0．01,P〈0．05）,但前两组之间无统计学差异（P〉0．05）。结论推拿结合膏摩治疗神经根型颈椎病安全有效。     

CASE REPORT: A monozygotic twin pregnancy after application of zona rubbing on a frozen--thawed blastocyst

Assisted hatching techniques enhance the success rate of implantationof in-vitro fertilized human embryos. We report here the successfultransfer of a frozen—thawed human blastocyst on whichwe applied a non-invasive zona rubbing technique (reductionof the thickness of the zona pellucida by gentle rubbing witha microneedle). The implantation in the uterus led to the deliveryof healthy monozygotic twins.     

摩腹法对肠易激综合征模型结肠组织脑肠肽表达的影响

[目的]从脑肠肽角度探讨摩腹法干预肠易激综合征(IBS)的作用机制。[方法]把新西兰白兔随机分为正常组、模型组和手法组,模型组和手法组用0～2℃冰水灌胃21 d以建立肠易激综合征,手法组运用摩腹法操作10 d,采用免疫组化方法对以上3组结肠组织P物质(SP)、血管活性肠肽(VIP)、胆囊收缩素(CCK)进行半定量分析。[结果]模型组结肠黏膜SP表达的阳性面积、不透光率密度值明显减少,VIP增多(P<0.05),经摩腹干预后,SP表达升高,VIP降低,与正常组比较无显著性差异(P>0.05),3组CCK表达无显著性差异(P>0.05)。[结论]结肠SP和VIP表达异常可能是IBS的致病因素之一,摩腹法可以通过调节局部肠道SP和VIP的功能来治疗IBS。     

Relevance of IgE,allergy and eye rubbing in the pathogenesis and management of Keratoconus

Keratoconus (KC) is an ectatic disease of the cornea characterized by localized thinning and protrusion causing irregular astigmatism, which can lead to significant visual impairment. KC has often been associated with allergy and/or atopy, which are immune-mediated inflammatory reactions primarily driven by IgE. A higher proportion of KC patients were reported to have history or suffer from systemic and/or ocular allergy with elevated allergen-specific IgE and/or total serum IgE. Eye rubbing, one of the risk factors for worsening of the disease and developing related complications in KC, is associated with IgE driven conditions. The current review enumerates and contextualizes the evidence related to IgE in mediating KC pathogenesis, including aberrant extra-cellular matrix remodeling. This review also discusses clinical strategies directed at modulating IgE-mediated responses in the management of KC, and the emerging academic and plausible clinical relevance of assessing serum and tear IgE (allergen-specific and total) status in improving the understanding of disease pathobiology, treatment planning, and prognosis.     

Enhanced,Perpendicular Liquid‐Crystal Alignment on Rubbed Films of a Coumarin‐Containing Polystyrene

We synthesized a series of polystyrene derivatives containing coumarin side groups using polymer analogous reactions. The liquid‐crystal (LC) alignment director for these polymer films was found to be perpendicular to the rubbing direction. The contrast ratio and anchoring‐energy values of these polystyrene derivatives were found to be much greater than those of polystyrene and poly(chloromethylstyrene), indicating that the coumarin side groups increase the aligning ability. For example, the anchoring energy of a polymer with 82 mol‐% of coumarin‐containing monomeric units, compared to polystyrene, is about 7 × 10^?5 J · m^?2 and 1 × 10^?7 J · m^?2, respectively.

     

强化“六字诀”肺康复操对稳定期COPD疗效影响的多中心临床随机对照研究

目的观察强化"六字诀"肺康复操联合常规西医疗法治疗稳定期慢性阻塞性肺疾病(COPD)的临床疗效并探寻优化整合后的中医肺康复方案。方法将150例COPD稳定期患者随机分为对照组30例(予常规西医疗法)、康复1组30例(予常规西医疗法加"六字诀"操)、康复2组30例(予常规西医疗法加"六字诀"操,强化呬字诀)、康复3组30例(予常规西医疗法加"六字诀"操,强化摩腹)、康复4组30例(予常规西医疗法加"六字诀"操,强化呬字诀及摩腹)。各组疗程均为1年,观察中医证候积分、汉密尔顿心理问卷(HAMA与HAMD)积分变化情况,并对可能影响疗效的多因素进行Logistic回归分析。结果 1治疗前后组内比较,5组的中医证候积分差异均有统计学意义(P0.05)。组间治疗后比较,康复各组与对照组中医证候积分差异均有统计学意义(P0.05);康复4组分别与康复3组、康复1组比较,差异有统计学意义(P0.05);康复2组分别与康复3组、康复1组比较,差异有统计学意义(P0.05);康复4组与康复2组比较,差异无统计学意义(P0.05)。2治疗前后组内比较,5组的HAMA及HAMD积分差异均有统计学意义(P0.05)。组间治疗后比较,康复各组与对照组HAMA及HAMD差异均有统计学意义(P0.05);康复4组分别与康复2组、康复1组比较,差异有统计学意义(P0.05);康复3组分别与康复2组、康复1组比较,差异有统计学意义(P0.05);康复4组与康复3组比较,差异无统计学意义(P0.05)。3回归分析后得出,与综合疗效相关的因素为分组(P0.05)与病程(P0.05),提示较好的临床疗效与进行以"六字诀"操为基础的功法锻炼及较短的病程相关。结论强化"六字诀"(强化呬字诀及摩腹)肺康复操联合西医常规疗法治疗稳定期COPD,可显著改善患者的临床症状及焦虑、抑郁状态。     

Comparing sterile bag rubbing and paint on technique in skin preparation of the hands

Background: The aim of this study was to compare two techniques for surgical site skin preparation in hand surgery. Methods: We compared the standard sponge paint technique versus a plastic bag immersion technique using a 10% povidone–iodine with alcohol solution (Betadine, ORION Laboratories Pty Ltd, Balcatta, WA, Australia) to prepare surgical site skin for hand surgery. This sterile bag rubbing technique involves using a sterile plastic bag filled with 60 mL of Betadine solution to immerse the subjects' hand. Samples were taken from 10 subjects for bacteria colony‐forming unit (CFU) counts before and 3 min after surgical site preparation in each group. Outcome measures were preparation time and CFU reduction with a plate impression test using commercially available agar slides. Results: The sterile bag rubbing technique significantly reduced (P < 0.0001) the time required for surgical site skin preparation (28 s) compared with the standard technique (86 s). Both techniques were found to have similar efficacy in the reduction of CFU. Conclusions: The sterile bag rubbing technique is a quicker alternative method for surgical site preparation in hand surgery and has comparable efficacy to the widely practised standard paint‐on technique.     

In vitro study to determine decontamination of 3,5-dichloro-2,4,6-trifluoropyridine (DCTFP) from human skin

This in vitro study determined the decontamination potential of soap and water, D-TAM skin cleanser, corn oil and the O’Dell reactive skin decontamination system to remove 3,5-dichloro-2,4,6-trifluoropyridine (DCTFP) from human skin after short exposure periods (10 and 30 min). The main result turned out to be the rapid volatility of DCTFP where half of the dose evaporated within 10 min and most of the dose was evaporated after 30 min. This rapid volatility was confirmed in an additional study where DCTFP rapidly evaporated from inert plastic disks (70% loss in 10 min).     

屈膝点按扣揉推拿手法配合微波治疗膝关节鹅足滑囊炎46例临床研究

[目的] 观察屈膝点按扣揉推拿手法配合微波治疗膝关节鹅足滑囊炎的疗效。[方法] 将46例膝关节鹅足滑囊炎患者随机分为治疗组和对照组,治疗组采用屈膝点按扣揉推拿手法配合微波治疗,对照组采用针灸配合微波治疗,两组10 d后通过膝关节评分标准(HSS)、疼痛视觉模拟量尺评分(VAS)评分标准,压痛测试仪分析疗效。[结果] 治疗后HSS膝关节评分较治疗前明显缓解(P<0.05),VAS疼痛评分明显改善(P<0.05),及压痛测试仪测量膝关节压痛明显缓解(P<0.05)。[结论] 两组均有效,但对于患者主观疼痛的缓解及压痛的缓解治疗组优于对照组。