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991.
Epidural abscess is a well-recognised but rare complication of epidural catheter placement. We have found only five previous reports of epidural abscess from noncatheter-related administration of steroids and/or local anaesthetic. We describe a further case which led to critical illness and emphasise the association between diabetes mellitus and epidural infection. 相似文献
992.
Depth of epidural space in children 总被引:1,自引:0,他引:1
M. A. Hasan MB ChB DA FRCA R. F. Howard BSc MB ChB FRCA A. R. Lloyd-Thomas MB BS FRCA 《Anaesthesia》1994,49(12):1085-1087
993.
Hemophilia A: genetic prediction and linkage studies in all available families in Finland 总被引:1,自引:0,他引:1
Anna-Elina Lehesjoki Pertti Sistonen Vesa Rasi Albert de la Chapelle 《Clinical genetics》1991,39(3):199-209
RFLP studies were done in 82 (75%) of all known hemophilia A families in the Finnish population (approximately 5 million). Two intragenic RFLPs (Bc1I/F8A, XbaI/p482.6) and two extragenic markers (TaqI/St14, Bg1II/DX13) were used. Among 263 females at risk, carriership could be evaluated with an intragenic marker in 47% and with an extragenic marker in 26%. In 27% of the females, carriership could be neither excluded nor confirmed; 68% of these females were relatives of an isolated patient. Eight recombinations between the factor VIII gene (F8C) and DXS52 (lod 25.02 at theta max 0.06), eight recombinations between F8C and DXS15 (lod 21.91 at theta max 0.05), and two recombinations between DXS52 and DXS15 (lod 33.56 at theta max 0.01) were found. Using multipoint linkage analysis, the most likely order of loci supported by the data was: F8C-DXS15-DXS52-DXS134. RFLP segregation analysis provides a highly useful method of carrier detection and prenatal diagnosis of hemophilia A, but its limitations must be carefully taken into account. 相似文献
994.
995.
This investigation utilized prospective survey data to examine the influence of a research incentive ($100) and requirement (videotaping) on decisions to participate in prevention research. Individuals were significantly attracted by the incentive, and marginally deterred by the requirement. Interaction analyses revealed that the positive incentive effect was stronger among prospective participants with less education and who were otherwise less likely to participate. These findings indicate that monetary incentives can be useful for increasing participation rates, and may help reduce sampling bias by increasing rates most strongly among individuals who are typically less likely to take part in research projects. 相似文献
996.
应用因特网对SARS病毒M蛋白B细胞抗原表位的预测 总被引:7,自引:1,他引:6
目的:预测SARS冠状病毒M蛋白的B细胞表位。方法:采用EMBOSS软件结合Hopp&woods亲水性参数、Janin可及性参数、极性参数、柔韧性参数及二级结构方案对SARS冠状病毒M蛋白的B细胞表位进行了预测,并用吴玉章等已建立的B细胞表位预测方法进行评述。结果:SARS冠状病毒M蛋白B细胞识别的表位可能位于第3~13和153~166位氮基酸等区域内或附近,这2个被预测的表位均含有β—转角和无规卷曲结构。结论:该研究对应用合成肽抗原进行SARS早期诊断研究及相关抗体的制备具有重要指导意义。 相似文献
997.
移植肾彩色多普勒血流超声与肾穿刺活检的对照研究 总被引:2,自引:0,他引:2
将彩色多普勒血流超声与移植肾活检结果相对照。评价无创性CDFI对移植肾排异反应的诊断价值。结果:不同病理状态下移植肾的阻力指数有所不同。急性排异和慢性排异反应组的RI值明显高于正常组。两次肾活检提示由急性排异转为慢性排异反应的同一患者,CDFI的动态观察显示,RI值明显增高。 相似文献
998.
链球菌蛋白G应用于ELISA的实验研究 总被引:2,自引:0,他引:2
对酶标记链球菌蛋白G(SPG)在ELISA的应用条件进行了研究并与SPA作了系统比较。SPG与IgG结合受温度影响,37℃结合活性高于室温和4℃;反应时间定为2h反应溶液pH值升高,SPG的结合力亦增强。在同等条件下与酶标记SPA进行比较,结果表明SPG对小鼠单克隆抗体、羊抗人、兔抗IFN-γ和驴抗兔Igg以及牛、大鼠和人IgG的结合力均明显高于SPA。SPG用于大鼠血清抗IFN-γ抗体的检测,其阳性率和抗体滴度均大大高于SPA。因此,SPG作为一种广谱的、高亲和力的IgG结合物,是应用于ELISA的理想的替代二抗。 相似文献
999.
Prevalence of Hepatitis A, B, and C markers in school children of a rural area of Crete, Greece 总被引:2,自引:0,他引:2
Christos Lionis Effie Frangoulis Maria Koulentakis Evangelos Biziagos Elias Kouroumalis 《European journal of epidemiology》1997,13(4):417-420
Objective: To determine the prevalence of hepatitis A, B, and C markers in children who were attending junior and senior high schools in a high risk area in rural Crete, Greece. Methods: Three-hundred and thirty-four children who attended the three junior schools and one senior high school in the Agios Vassilios province of Southern Crete were invited to participate in the study. Three hundred and four of them were tested for hepatitis A, B, and C markers. Hepatitis B (HBV) markers (HBsAg and anti-HBc) as well as hepatitis A (anti-HAV) and hepatitis (anti-HCV) antibodies were tested with commercial enzyme-linked immunosorbent assay kits. Results: Six of the 304 children (1.97%) were found to be positive for anti-HAV, 1 (0.33%) to HBsAg, 7 (2.30%) to anti-HBc and none were found positive for anti-HCV. No significant differences were seen between the prevalence of anti-HAV antibodies in males (2%) and females (1.95%), and of anti-HBc antibodies in males (3.33%) and females (1.30%). Conclusions: The very low prevalence of anti-HAV is obviously due to the improved conditions of hygiene and it raises the question of the possible emergence of this disease at an older age and therefore appropriate preventative strategies should be considered. The low endemicity of hepatitis B in Crete in contrast to other areas of Greece also calls for a vaccination policy probably during adolescence. The absence of hepatitis C markers in the children in contrast to the observed higher prevalence of HCV-infected people in the adult population in the same rural area raises questions regarding possible sources of transmission of hepatitis C during the preceding years. 相似文献
1000.
拮氟锐对大鼠肠道氟吸收及微量元素的影响 总被引:1,自引:1,他引:0
拮氟锐是由硼、微量元素和中药制成的抗氟药物。本文应用肠道原位灌流技术。观察了拮氟锐对大鼠肠道氟吸收的干预作用及微量元素的影响。结果透明:拮氟锐可促进肠道BF4的形成,使氟吸收量减少,血氟降低。同时,拮氟锐可拮抗氟所致的微量元素的降低。与硼锌组比较,拮氟锐的抗氟作用效果更明显。 相似文献