Flow Cytometry Analysis of Celullar DNA Content of the Parotid Pleomorphic Adenoma

ＦｌｏｗＣｙｔｏｍｅｔｒｙＡｎａｌｙｓｉｓｏｆＣｅｌｕｌａｒＤＮＡＣｏｎｔｅｎｔｏｆｔｈｅＰａｒｏｔｉｄＰｌｅｏｍｏｒｐｈｉｃＡｄｅｎｏｍａＺｈａｎｇＹｕａｎ（张圆）ＹａｎｇＪｉａｎｒｏｎｇ（杨建荣）＊ＺｈｏｕＺｈｅｎｙｉｎｇ（周振英）＊＊Ｄｅｐａｒ...     

Pleomorphic giant cell carcinoma of the pancreas: A review of nine cases

Nine cases of pleomorphic giant cell carcinoma of the pancreas collected over a 26-year period are analyzed. The tumor presents a distinctive histology. The head of the pancreas appears to be the predominant site of the lesions in this study, and the cell origin is considered to be the ductal epithelium. Its clinical manifestation and rapid, fatal course of usually two months are almost indistinguishable from the more conventional pancreatic adenocarcinoma.     

Myoepithelioma of the head and neck: case report and review

The clinical, light, and ultrastructure features of a myoepithelioma occurring on the hard palate of a 24-year-old woman are presented and compared with 41 myoepithelioma of the head and neck described in the English literature. These 42 tumors (39 benign and 3 malignant) occurred in individuals from 14 to 81 years of age, affected both sexes about equally, and most often presented as a slowly enlarging, asymptomatic mass. The parotid gland and palate were the most common sites of occurrence. The tumors are typically circumscribed and encapsulated, vary from 1 to 5 cm in the greatest dimension, and are composed of spindled and/or plasmacytoid myoepithelial cells. Prognosis correlates with histologic appearance and parallels that of the pleomorphic adenoma. Conservative excision with a margin of uninvolved tissue is curative. The differential diagnosis and histogenic relationship with other closely related neoplasms are discussed.     

Pleomorphic rhabdomyosarcoma of the uterus in a postmenopausal patient

Pure rhabdomyosarcomas occurring in the adult uterus are very rare, with poor prognosis. We present a case of a 67-year-old woman with postmenopausal vaginal bleeding caused by pleomorphic rhabdomyosarcoma of the uterus, treated with hysterectomy, bilateral salpingooophorectomy, pelvic/paraaortic lymphadenectomy and partial sigmoidectomy. Postoperative chemotherapy (Doxorubicin) was given according to protocol. Followup examinations one year after surgery revealed no abnormalities or tumor recurrence. The rarity of this histological entity makes the presented case worthy of publication.(Pathology Oncology Research Vol 12, No 2, 102–104)     

Pleomorphic xanthoastrocytoma: report of a case with light and electron microscopy

A case of pleomorphic xanthoastrocytoma is reported with light and electron microscopic findings. This unusual tumor arose in a 15-year-old male. The tumor consisted predominantly of nests of xanthomatous cells and plump spindle cells surrounded by a prominent reticulin network. There was considerable cellular pleomorphism with abundant bizarre giant cells and multinucleated cells. Occasional mitoses were present. Electron microscopy and immunoperoxidase localization of glial fibrillary acidic protein (GFAP) confirmed the glial nature of the tumor. Recognition of this tumor is important. Despite its “malignant” appearance, the tumor characteristically has a relatively good prognosis and should not be confused with highgrade gliomas or meningeal sarcomas, which require aggressive therapy.     

Ultrastructural Observation of Calcification in a Pleomorphic Adenoma of the Parotid Gland

A pleomorphic adenoma was examined by electron microscopy. Calcification was found in a lumen and in epithelial cells and consisted of needle-shaped crystals that contained calcium and phosphorus and were probably apatite. Small collections of crystals in the lumen, which were often associated with membranous cellular debris, appeared to form larger calcified masses by fusion. Collections of crystals were seen in vacuoles in adluminal cells. The calcification in the lumen may have started on membranous cellular debris, and that in the adluminal cells may have arisen either by endocytosis of luminal material or by autophagocytosis. The calcification appears to relate to the old age of the tumor.     

Value of cytological imprints in the diagnosis of atypical lipomatous tumor

The diagnosis of atypical lipomatous tumor by biopsy, requires careful examination of several slides, in order to look for atypical cells. We suggest that imprints of lipomatous tumors may play a complementary role in such a search, and report a case of a 74-yr-old woman with an atypical lipomatous tumor of the left thigh, in which imprints helped to make the diagnosis..     

In situ adenocarcinoma ex pleomorphic adenoma of the lacrimal gland

A case of an in situ adenocarcinoma of the lacrimal gland that developed in a recurring pleomorphic adenoma is presented. Six years after incomplete resection of a pleomorphic adenoma, the patient complained of a progressive swelling of her right upper eyelid without pain or diplopia. An orbital computerized tomography scan showed an inhomogeneous mass in the right lacrimal gland region without bone involvement. After local excision of the in situ adenocarcinoma ex pleomorphic adenoma, the tumour has been in control for over 6 years.     

Metastatic malignant teratoid medulloepithelioma – a case report and review of the literature

Medulloepitheliomas are rare congenital tumours arising from the epithelium lining the medullary tube. They are usually detected in the first decade of life. They may be teratoid or non-teratoid. Regional and distant metastases are rare. Extraocular extension of disease appears to be the most important prognostic feature. Surgical resection is the usual mode of treatment. The role of other adjuvant modalities is as yet unclear.     

腮腺多形性腺瘤改良术式与传统术式的对比研究

目的:探讨采取美容切口,保留耳大神经、腮腺咬肌筋膜、腮腺导管和部分腮腺的改良腮腺切除术治疗腮腺多形性腺瘤的临床效果和方法.方法:将我院2000-2009年收治的腮腺多形性腺瘤患者120例分为2组,第1组采用美容切口,保留耳大神经、腮腺咬肌筋膜、腮腺导管和部分腮腺的改良腮腺切除术,第2组采用传统腮腺切除术.术后随访3～5...