Cohen syndrome: fertility in a female patient

In this report we describe fertility in an adult female with Cohen syndrome. She gave birth to a son, now 1.5 years old, with discrete facial stigmata and slight psychomotor retardation.     

精神病患者家属的心理分析及护理

作者采用询问交谈的方法对精神病患者家属的心理状态进行了调查分析，大多数精神病患者家属存在着焦虑、急躁、自卑、厌恶、矛盾、无能为力等心理。同时，针对性地提出了以安慰、鼓励、心理启发、支持为主的护理方法和措施。     

The Mental Health of Homeless Children

The literature addressing the mental health of homeless children is critically reviewed. Higher rates of behavioral, emotional, and cognitive problems have been reported for this population, but research results are qualified by significant methodological problems. Minimal attention has been given to the development and evaluation of specific intervention and prevention strategies. Recommendations are made for conducting research that will overcome previous methodological problems and focus more directly on identifying risk and protective mechanisms within the population of children exposed to homelessness.     

以中医神志学说辨析百合病

运用神魂魄意志五神与五藏、五官、五体的配属关系．结合文献对百合病命名、病位、症状、病机及愈期判断加以探讨。提出百合病属中医神志失和类病变，由热病伤阴，余邪未尽．心肺阴虚，神志失养，加之情怀不畅，气郁不舒，百脉失调，形神失和而发病。     

中药结合心理干预治疗不安障碍40例

[目的]探索不安障碍治疗的有效途径。[方法]采用中药结合心理干预治疗不安障碍患者40例。[结果]显效31例(77·5%)、有效7例(17·5%)无效2例(5·0%)。SDS、CMI有显著性差异。[结论]中药结合心理干预治疗不安障碍疗效显著。     

心理咨询门诊与普通专科门诊抽样对照分析

目的调查本院心理咨询门诊与普通专科门诊就诊疾病谱的差异,了解两者在精神分裂症治疗上的差异以及对预后的影响。方法以1/20抽取1995～2002年间的门诊病例进行统计分析,其中心理咨询门诊病例79份,普通专科门诊病例143份。自行设计表格对就诊者的性别、年龄、初诊诊断和服药、住院情况进行统计,比较两者就诊疾病谱的差异,以及两者在精神分裂症治疗上的差异和对预后的影响。结果(1)心理咨询门诊就诊者以心境障碍和神经症为主(分别达25%和27%),普通专科门诊以精神分裂症为主(48%,t=14．66,P＜0．005)；(2)在精神分裂症的治疗上,心理咨询门诊第二代抗精神病药(SGAs)的应用率较高(50%vs 14%,P＜0．005),两处就诊者的预后也存在差异。结论心理咨询门诊与普通专科门诊在初诊中存在一定的分工；两者对精神分裂症治疗存在差异,这种差异可能直接导致精神分裂症的预后,我国有待建立规范的精神分裂症治疗指南；全社会对非重性精神疾病的重视程度仍有待加强。     

The Relationship between maternal education and mental retardation in 10-year-old children

We conducted a case-control study of mental retardation (MR) in which case children (aged 10 years) were identified from existing records at multiple sources, primarily the public school systems. Control children were drawn from a roster of public school students not receiving special education services. We found that maternal educational level at the time of delivery was strongly and inversely related to a form of MR not accompanied by other serious neurologic conditions. For this isolated form of MR, maternal educational level was by far the most important predictor from among seven sociodemographic variables examined. There was a significant race-education interaction that indicated a steeper gradient in risk among white mothers than among black mothers. Relative to children of white mothers with 12 years of education, all children of black mothers, except those whose mothers had 16 or more years of education, were at increased risk. The results may be useful as a guide for selecting high-risk groups as candidates for early childhood intervention programs.     

SCL-25 and recognition of mental disorders reported by primary health care physicians

A marked proportion of primary care patients have mental disorders and problems that remain unrecognized by the patients and their general practitioners. There is furthermore a great variation in the physicians’ ability to detect mental disorders. The aim of the present study was to find out the overall prevalence of mental disorders among patients receiving primary health care. The material consisted of 1000 randomly selected adult patients attending primary care facilities in Turku. The mental disorders were assessed by using the Symptom Checklist (SCL-25) and by general practitioners. According to the SCL-25, one fourth of the sample had a mental disorder. Only two fifths of them could be identified by the general practitioners.     

Psychiatric aspects of Down's syndrome

In a survey study of psychiatric morbidity, based on a representative sample from the Danish mental retardation register, 44 adults with Down's syndrome (DS) were compared with 258 other mentally retarded adults. Assessed by the parameters psychiatric disorder, behaviour problems, neurotic traits, and deviant social interaction, the DS group functioned better on all parameters. However, male and female DS patients were very different, the females constituting a superior well-functioning group while the males had major problems in every area. High prevalence rates of dementia and infantile autism were found in the DS group. General function rapidly decreased with age in DS patients.     

142例先天性智能发育不全患儿的遗传学研究

应用细胞遗传学和皮纹分析方法对142例先天性智能发育不全患儿进行了研究。其中,120例正常核型,22例异常核型。异常核型46,XY,t(1;3;21)(1pter→1q32.1∶∶21p11.2→21qter;3 qter→3p26.2∶∶1 q32.1→1 qter)和45,X/45,X,-22,+der(22)t(Y;22)(22qter→22p11.1∶∶Yq11.1→Yq11.2)两种核型国内尚未见报道。皮纹分析结果表明56.7%的患者有1项以上异常皮纹;染色体异常患者均有2项以上异常皮纹;先天愚型患者有“特定”的皮纹改变。