Auger injuries

Attention is drawn to accidents caused by the auger used on the farm and in industry. The worst machine is the portable grain auger which produces severe, mutilating injuries of the forearm, hand or lower limb. There are large numbers of these portable conveyors in the Prairies, and probably 5000 or more in Manitoba alone. It is likely that some 120 amputations occur each year on the farm, and many of these are due to augers.     

211例住院新生儿病因及死因分析

本文对住院211例新生儿疾病进行了病因及死因分析。特别对来自农村新生儿的感染性疾病导致死亡率高的问题进行了分析讨论。因此,积极做好儿童保健工作、预防早产,对降低新生儿患病率和死亡率极为重要。     

12种β—内酰胺类抗生素对β—内酰胺酶的稳定性研究

实验采用紫外分光光度法测定了(1)11株国际标准产酶菌的β—内酰胺酶活性;(2)11种β—内酰胺酶对12种β—内酰胺类抗生素的相对水解率;(3)CP—45899对11种酶的抑酶率。结果表明:酶K—1和TEM—2活性分别为699和319单位外,其余酶活性在22—72单位之间。12种抗生素中,第三代头孢菌素(除CPZ外)的酶稳定性最好;第二代头孢菌素中CXM的酶稳定性明显优于CMD和CPZ(P<0.01)。第一代头孢菌素和青霉素类易被酶水解。CP—458991ug/ml对多种β—内酰胺酶显示抑制作用,对CRD、CMD具有保护作用。     

甲状腺机能亢进的病因学研究

对15例甲亢病人甲状腺进行病理和免疫组化的研究。病理切片观察为典型甲亢病理变化,免疫组化证实其中6例有淋巴滤泡,并在淋巴滤泡中可见为酶标记 IgG 着色的淋巴细胞。对国际标准品 LATS—B 和国内提取 LATS—天津两种甲状腺刺激自身抗体,进行一系列免疫学试验,实验结果证明 LATS—B 为 IgG 的多克隆免疫球蛋白,LATS—国内不是单一 IgG,尚含有 IgM。经 EL1SA 试验首次证实神经节苷脂Ⅱ、Ⅳ和Ⅴ型都能与上述两种 Tsaab 结合,且Ⅳ型与 LATS—B 结合较好。     

Characterization of an active, non-myristylated, cytoplasmic form of the lymphoid protein tyrosine kinase pp56lck

pp56lck is a member of the src family of tyrosine kinases mainly expressed in T lymphocytes. Src tyrosine kinases have been implicated in the control of cell growth and differentiation in different cell types, but the mechanism of regulation of these enzymes is poorly understood. In order to characterize the distinct species of pp56lck, we have produced high yields of enzymatically active wild type pp56lck using the eukaryotic baculovirus expression system in Spodoptera frugiperda insect cells (Sf9). We find that the various species of baculoviral pp56lck are not only differentially phosphorylated (on serine and tyrosine residues) but also heterogeneously myristylated. Surprisingly a non-myristylated, very active form of bv-pp56lck is found in the cytoplasm of Sf9 cells. Fractionation of T cells reveals that cytoplasmic pp56lck exists in T lymphocytes as well.     

低剂量对比剂MSCT脑动脉成像的可行性及临床应用

目的探讨低剂量对比剂16层螺旋CT脑动脉成像的可行性及临床应用。方法152例MSCTA病例,行Test-Bolus测试确定脑动脉延时扫描时间,再按46ml低剂量对比剂(优维显370mgI/ml)+40ml生理盐水注射行CT扫描,评价CTA图像质量以及临床应用价值。图像评价由显示动脉分支的级数不同按3分制评分。结果脑动脉最大强化均值485.53±83.78(HU),CTA图像质量评分:3分144例(94.7%),2分7例(4.6%),1分1例(0.7%),共发现动脉瘤19例动静脉畸形12例,烟雾病1例,动脉狭窄37例。结论16层螺旋CT低剂量对比剂脑动脉成像图像质量高,能降低对比剂毒性,具有较高的临床实用价值。     

四川峨眉山地区二叠系与三叠系界线微量元素地球化学研究

通过对峨眉山地区地层剖面的实地观察和测量,采集界线附近的粘土岩,分析了该区微量元素地球化学的组成特征,并通过对稀土元素标准化图解和其它微量元素的研究,利用微量元素的示踪作用以及微量元素地球化学异常,初步探讨了界线粘土岩的来源,为全球二叠—三叠界线研究工作提供依据。     

Responses to a Modified Visual Cliff by Pre-Walking Infants Born Preterm and at Term

ABSTRACT

The purpose of this study was to examine, using a modified visual cliff apparatus, possible perceptual differences at crawling age between infants born preterm and infants born at term without documented visual or motor impairments. Sixteen infants born at term and 16 born preterm were encouraged to crawl to their caregivers on a modified visual cliff. Successful trials, crossing time, duration of visual attention, duration of tactile exploration, motor strategies, and avoidance behaviors were analyzed. A significant surface effect was found, with longer crossing times and longer durations of visual attention and tactile exploration in the condition with the visual appearance of a deep cliff. Although the two groups of infants did not differ on any of the timed measures, infants born at term demonstrated a larger number of motor strategies and avoidance behaviors by simple tally. This study indicates that infants born at term and those born preterm can perceive a visual cliff and adapt their responses accordingly.