Outcomes of using Firebird rapamycin eluting stents in routine coronary intervention practice: one-year results from the pilot study of Firebird in China registry

Recent clinical trials with rapamycin-eluting stents have shown very low restenosis rates.1-4 However, the higher penetration of drug eluting stent (DES) in China is being limited by the high costs of these imported devices, especially when considering multiple stenting.     

认知行为干预对子宫内膜癌手术患者术后病耻感及自我效能的影响

目的 探讨认知行为干预对子宫内膜癌手术患者术后病耻感及自我效能的影响.方法 选取2017年1月—2019年12月医院收治的子宫内膜癌手术患者80例为研究对象,按照组间基本特征具有可比性的原则分为对照组和观察组,各40例.对照组予以常规护理干预,观察组在对照组基础上给予认知行为干预,比较两组患者干预8周后病耻感及自我效能...     

细节管理在老年留置普通硅胶胃管患者鼻饲饮食中的应用

目的 研究细节管理减少老年留置普通硅胶胃管患者鼻饲饮食后并发症、减少感染及死亡率的作用.方法 选取80例老年留置普通硅胶胃管患者,随机分为对照组40例与干预组40例,对照组患者鼻饲饮食实施常规管理,干预组患者鼻饲饮食实施管理,比较两组干预效果.结果 干预组发生胃肠道并发症6例,无堵管现象,肺部感染2例;对照组发生胃肠道...     

急性心肌梗死自溶现象及其影响因素分析

目的分析急性心肌梗死（AMI）梗死相关血管（IRA）的自溶（SR）现象,探讨SR现象的影响因素。方法连续观察205例未予静脉溶栓治疗,直接行急诊冠状动脉造影的AMI患者,根据TIMI血流分为自溶组（前向血流TIMI 2-3级）和非自溶组（前向血流TIMI 0-1级）,分析其临床和造影特点,并寻求发生SR的影响因素。结果自溶组共49例（23.9%）。与非自溶组比较,一般临床情况差异无统计学意义（P〉0.05）,但自溶组发生梗死前心绞痛的比例较高（38.8%比22.4%,P〈0.05）。而非自溶组多支病变和存在侧支循环的比例高于自溶组（P〈0.05）。Logistic回归分析则提示多支病变和侧支循环是发生SR现象的独立影响因素。结论SR是AMI患者较常见的现象,其独立影响因素是多支病变和侧支循环。     

护理干预对冠心病患者生活质量的影响

目的观察护理干预对冠心病患者生活质量的影响。方法将100例老年冠心病患者随机分为干预组和对照组,每组各50例。两组均实施常规护理,干预组在此基础上给予健康教育、康复训练、心理护理等护理干预,并于护理干预8w末采用西雅图心绞痛调查量表进行评估分析。结果护理干预8w末,干预组西雅图心绞痛调查量表躯体活动受限程度评分显著高于对照组（P〈0．05）;治疗满意程度、疾病认识程度和总分评分显著高于对照组（P〈0．01）。结论对冠心病患者实施完善的护理干预体系可提高患者的生活质量。     

In-Hospital Patient Education Markedly Reduces Alcohol Consumption after Alcohol-Induced Acute Pancreatitis

Although excessive alcohol consumption is by far the most frequent cause of recurrent acute pancreatitis (AP) cases, specific therapy is still not well established to prevent recurrence. Generally, psychological therapy (e.g., brief intervention (BI)) is the cornerstone of cessation programs; however, it is not yet widely used in everyday practice. We conducted a post-hoc analysis of a prospectively collected database. Patients suffering from alcohol-induced AP between 2016 and 2021 received 30 min BI by a physician. Patient-reported alcohol consumption, serum gamma-glutamyl-transferase (GGT) level, and mean corpuscular volume (MCV) of red blood cells were collected on admission and at the 1-month follow-up visit to monitor patients’ drinking habits. Ninety-nine patients with alcohol-induced AP were enrolled in the study (mean age: 50 ± 11, 89% male). A significant decrease was detected both in mean GGT value (294 ± 251 U/L vs. 103 ± 113 U/L, p < 0.001) and in MCV level (93.7 ± 5.3 U/L vs. 92.1 ± 5.1 U/L, p < 0.001) in patients with elevated on-admission GGT levels. Notably, 79% of the patients (78/99) reported alcohol abstinence at the 1-month control visit. Brief intervention is an effective tool to reduce alcohol consumption and to prevent recurrent AP. Longitudinal randomized clinical studies are needed to identify the adequate structure and frequency of BIs in alcohol-induced AP.     

Comparing Digital Therapeutic Intervention with an Intensive Obesity Management Program: Randomized Controlled Trial

In this study, we evaluated whether the digital program Vitadio achieves comparable results to those of an intensive in-person lifestyle intervention in obesity management. This is a 12-month prospective, randomized controlled trial. Obese patients with insulin resistance, prediabetes or type 2 diabetes were included. The intervention group (IG) used Vitadio. The control group (CG) received a series of in-person consultations. Body weight and various metabolic parameters were observed and analyzed with ANOVA. The trial is ongoing and the presented findings are preliminary. Among 100 participants (29% men; mean age, 43 years; mean BMI, 40.1 kg/m²), 78 completed 3-month follow-up, and 51 have completed the 6-month follow-up so far. Participants significantly (p < 0.01) reduced body weight at 3 months (IG: −5.9 ± 5.0%; CG: −4.2 ± 5.0%) and 6 months (IG: −6.6±6.1%; CG: −7.1 ± 7.1%), and the difference between groups was not significant. The IG achieved favorable change in body composition; significant improvement in TAG (−0.6 ± 0.9 mmol/l, p < 0.01), HDL (0.1 ± 0.1%, p < 0.05), HbA1c (−0.2 ± 0.5%, p < 0.05) and FG (−0.5 ± 1.5 mmol/l, p < 0.05); and a superior (p = 0.02) HOMA-IR reduction (−2.5 ± 5.2, p < 0.01). The digital intervention achieved comparable results to those of the intensive obesity management program. The results suggest that Vitadio is an effective tool for supporting patients in obesity management and diabetes prevention.