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51.
IntroductionThe treatment of intestinal perforation caused by the SBC enters the small intestine in elderly patients is a challenge for urologists. The report is to share our experience of conservative treatment after a 90-year-old male with the suprapubic bladder catheter enters the small intestine.Presentation of caseBecause of the device was obstructed, a 90-year-old male went to our hospital with his family and requested to replace the SBC. When the fistula tube was replaced, it entered the intestine through the intestinal injury site instead of entering the bladder. During the hospitalization, the patient was given supportive treatments and the SBC was dynamically monitored daily and it was intermittently withdrawn out during this period. After the drainage volume was less than 10 mL for three consecutive days and the intestinal fistula was healing gradually, the catheter was taken out.DiscussionAccording to our experience, the common complications in the process include failure to pull out the SBC, abnormal position of the SBC, and poor drainage of the SBC. However, the drainage tube placing into the small intestine through the original hole of the suprapubic bladder fistula during the replacement process is quite rare. When elderly patients have traumatic small bowel perforation, the diagnosis and treatment of intestinal perforation in elderly patients was particularly important.ConclusionThe conservative treatment of intestinal perforation is suitable for elderly patients who are unsuitable or unwilling to undergo a surgical operation. Of course, it should be in accordance with the patient's condition to make the right choice of treatment. 相似文献
52.
Birgitte Hertz Carsten A. Brandt Michael B. Petersen Søren Pedersen Ulrich König Helle Strømkjær Peter K. A. Jensen 《Clinical genetics》1993,44(2):89-94
Hertz B, Brandt CA, Petersen MB, Pedersen S, König U, Strømkjær H, Jensen PKA. Application of molecular and cytogenetic techniques to the detection of a de novo unbalanced t(11q;21q) in a patient previously diagnosed as having monosomy 21.
Clin Genet 1993: 44: 89–94. © Munksgaard, 1993
The occurrence of complete autosomal monosomy in man is extremely rare and generally considered to be incompatible with life. Since the introduction of banding techniques in human cytogenetics, several cases of presumptive monosomy for chromosome 21 have nevertheless been reported. However, it has been suggested that most, if not all, of these cases may represent unbalanced translocations or other structural aberrations resulting in only partial monosomy 21. Here we describe a patient in whom full monosomy 21 was initially diagnosed by routine karyotyping. Re-examination with a combination of high resolution banding technique, chromosome painting and DNA polymorphism analysis demonstrated the presence of an unbalanced translocation between the long arms of chromosome 11 and 21, respectively. Consequently, the case was re-classified as a partial monosomy for the proximal long arm of chromosome 21. 相似文献
Clin Genet 1993: 44: 89–94. © Munksgaard, 1993
The occurrence of complete autosomal monosomy in man is extremely rare and generally considered to be incompatible with life. Since the introduction of banding techniques in human cytogenetics, several cases of presumptive monosomy for chromosome 21 have nevertheless been reported. However, it has been suggested that most, if not all, of these cases may represent unbalanced translocations or other structural aberrations resulting in only partial monosomy 21. Here we describe a patient in whom full monosomy 21 was initially diagnosed by routine karyotyping. Re-examination with a combination of high resolution banding technique, chromosome painting and DNA polymorphism analysis demonstrated the presence of an unbalanced translocation between the long arms of chromosome 11 and 21, respectively. Consequently, the case was re-classified as a partial monosomy for the proximal long arm of chromosome 21. 相似文献
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55.
谷氨酰胺对大鼠急性坏死性胰腺炎肠道细菌移位的影响 总被引:3,自引:2,他引:1
目的 观察谷氨酰胺(GLN)对急性坏死性胰腺炎(ANP)大鼠肠道细菌称位的影响。方法 将实验大鼠120只,随机分成对照组、ANP组及GLN组,每组各40只,ANP模型采用结扎胰胆管诱发,GLN组制作ANP后灌入GLN,观察3组肠粘膜组织学和DNA含量,肠系膜淋巴结,胰腺组织细菌培养及吖啶橙标记菌实验。结果 ANP后72h,肠粘膜出现明显损伤,DNA含量下降,肠系膜淋巴结,胰腺组织细菌培养计数明显升 相似文献
56.
Jenny Englert Lena Witzdam Dominik Söder Manuela Garay-Sarmiento Anton Joseph Anna M. Wagner Cesar Rodriguez-Emmenegger 《Macromolecular chemistry and physics.》2023,224(24):2300306
The immobilization of vesicles has been conceptualized as a method to functionalize biointerfaces. However, the preservation of their integrity post immobilization remains a considerable challenge. Interfacial interactions can cause vesicle rupture upon close surface contact and non-specific protein adsorption impairing surface functions. To date, immobilization of vesicles has relied solely on either entrapment or prior modification of vesicles, both of which require laborious preparation and limit their applications. This work develops a bioinspired strategy to pin vesicles without prior modification while preserving their intact shape. This work introduces antifouling diblock copolymers and ultrathin surface-attached hydrogels containing a brush-like interface consisting of a bottle brush copolymer of N-(2-hydroxypropyl) methacrylamide (HPMA) and N-(3-methacrylamidopropyl)-N,N-dimethyldodecan-1-aminiumiodide (C12+). The presence of positive charges generates an attractive force that pulls vesicles toward the surface. At the surface, the amphiphilic properties of the combs facilitate their insertion into the membrane, mimicking the harpooning mechanism observed in antimicrobial peptides. Importantly, the antifouling poly(HPMA) backdrop serves to safeguard the vesicles by preventing deformation and breakage. Using a combination of thermodynamic analysis, surface plasmon resonance, and confocal laser scanning microscopy, this work demonstrates the efficiency of this biomimetic system to capture vesicles while maintaining an antifouling interface necessary for bioapplications. 相似文献
57.
为探讨急性出血坏死性胰腺炎(AHNP) 感染的防治, 我们观察了头孢噻甲羧肟和生长抑素对AHNP早期细菌移位的影响。结果提示生长抑素具有肠粘膜屏障保护作用, 可能与其清除肠道氧自由基有关。我们还发现AHNP早期应用抗生素可减轻血行的细菌移位。 相似文献
58.
观察异丙酚复合芬太尼维持麻醉对脑代谢的影响。方法: 择期手术病人8 例, 芬太尼、硫贲妥钠、维库溴铵诱导插管, 静脉联接Graseby 微泵异丙酚8 mg/ (kg·h) , 芬太尼1 μg/ (kg·h)维持麻醉。连续监测MAP、心电图、脉搏氧饱和度和呼气末二氧化碳分压, 同步采集动脉血和颈内静脉血作血气分析, 计算动- 静脉氧含量差(Da - vO2) 和脑氧摄取率(ERO2) 。结果: 异丙酚麻醉维持平稳, Da - vO2 和ERO2 在给药30 min 、60 min 较气管插管后5 min 无明显改变, 有平均动脉压下降和心动过缓。结论: 异丙酚复合芬太尼维持麻醉可保持脑氧供需平衡稳定。 相似文献
59.
目的探讨基因重组碱性成纤维细胞生长因子(bFGF)对急性坏死性胰腺炎(ANP)犬肠道细菌移位的影响。方法杂种犬23只,分对照组(n=7)、ANP组(n=8)和bFGF组(n=8)。bFGF组犬复制ANP模型后,每日静脉注射bFGF(5μg/kg)。结果bFGF治疗后,ANP犬肠粘膜损伤明显减轻,脏器细菌培养阳性率下降50%,细菌移位数量减少93.3%-96.7%,肠粘膜蛋白质、DNA含量显著增加(P<0.05),丙二醛含量明显减少(P<0.05)。结论bFGF可显著减少ANP时肠道细菌移位,其机制可能是通过增加肠粘膜蛋白质合成,促进肠粘膜损伤修复。 相似文献
60.
Ayme S Macquart-Moulin G Julian-Reynier C Chabal F Giraud F 《Neuromuscular disorders : NMD》1993,3(5-6):571-574
Recent developments in genetics are likely to exacerbate the ethical issues in clinical practice, especially with regard to privacy and disclosure of genetic information. To evaluate the behaviour of patients with respect to transmitting carrier information, we undertook a survey of 283 families with a balanced chromosomal rearrangement as a model. In these families, 1816 relatives were considered at risk and 806 of them were karyotyped (44.4%). The percentage of karyotypes performed is significantly related to the number of living children of the index couple, the reason for referral, the nature of the anomaly, the training of the counsellor and the age of the index case. This study shows the limits of the screening of at risk individuals within families, based on the willingness of the patients, and addresses practical and ethical issues around family disclosure in medical genetics. 相似文献