Immediate flap increases patient safety for deep sternal wound infection: A meta-analysis

Deep sternal wound infection is a severe complication after cardiac surgery. We performed a meta-analysis evaluating the impact of immediate flap and NPWT on mortality and length of hospital stay. The meta-analysis was registered (CRD42022351755). A systematic literature search was conducted from inception to January, 2023, including PubMed, EMBASE, Cochrane Library, ClinicalTrials.gov and EU Clinical Trials Register. The main outcome were in-hospital mortality and late mortality. And additional outcomes were length of stay and ICU stay time. A total of 438 patients (Immediate flap: 229; NPWT: 209) from four studies were included in this study. Immediate flap was associated with lower in-hospital mortality (OR 0.33, 95% CI 0.13-0.81, P = .02) and length of stay (SMD −13.24, 95% CI −20.53 to −5.94, P = .0004). Moreover, pooled analysis demonstrated no significant difference was found in two groups in terms of late mortality (OR 0.64, 95% CI 0.35-1.16, P = .14) and ICU stay time (SMD −1.65, 95% CI −4.13 to 0.83, P = .19). Immediate flap could reduce in-hospital mortality and length of stay for patients with deep sternal wound infection. Flap transplantation as soon as possible may be advised.     

以旋髂深血管为蒂的髂骨瓣和血管束联合移植的应用解剖学(治疗股骨头缺血性坏死的新术式)

在41侧成人尸体上观测了旋髂深血管的起始和外径。依据旋髂深血管的髂骨支和腹壁肌支的局部解剖学,设计了以旋髂深血管为蒂的髂骨瓣和血管束联合移植治疗股骨头缺血性坏死的新术式,并讨论了该术式的意义及应用解剖学要点。     

甲状腺手术新麻醉点与颈深部结构的关系

目的：研究甲状腺手术新麻醉点与颈深部结构的关系。方法：３０侧成人标本，分层解剖观察新麻醉点与颈前部深层周围结构的毗邻关系，测量了主要神经血管距麻醉点的距离。结果：注射５ｍｌ染液（浅层３ｍｌ，深层２ｍｌ）着色的结构有胸锁乳突肌前缘、肩胛舌骨肌上腹、胸骨甲状肌上部、甲状舌骨肌下部；颈袢、颈动脉鞘前壁、甲状腺上动、静脉；喉上神经喉外支和甲状腺侧叶上极。结论：①５ｍｌ组迷走神经、颈交感干、膈神经、臂丛和喉返神经均未着色；②１０ｍｌ组（浅深层各５ｍｌ）迷走神经、颈交感干轻染。膈神经和颈神经根未着色     

Effect of low and high frequency thalamic stimulation on sleep in patients with Parkinson's disease and essential tremor

Continuous high frequency stimulation of the ventral intermediate nucleus of the thalamus (Vim), delivered through surgically implanted quadripolar electrodes, alleviates tremor in Parkinson's disease (PD) and essential tremor (ET). The Vim is adjacent to the thalamic reticular nuclei, where sleep spindles originate according to animal models. In order to determine whether Vim stimulation affects sleep spindles, six patients (4 PD, 2 ET), aged 60-69 years, were recorded on a control night and a stimulation night (130 Hz, 2-3 V; right stimulation in five patients and bilateral stimulation in one patient). Stimulation did not modify sleep quality or architecture. Sleep spindles were present and symmetrical in five out of six patients under stimulation. However, in one patient with a sustained 'thalamotomy-like effect' that abolished tremor, spindles were asymmetrical even without stimulation. In each patient, spindle density was similar on both nights (mean+/- SEM: 2.25+/-0. 61 spindles per min of stage 2 sleep vs. 1.84+/-0.31). In an attempt to promote sleep two different patterns of stimulation were applied in the region of ventrooralis posterior and reticularis nuclei in five patients in the awake state. Continuous low frequency stimulation (5 Hz, 0.1 V), and repeated trains of 15 Hz for 1 s every 15 s mimicking the pattern of physiological spindles, each failed to induce sleep or cortical synchronization. We conclude that Vim stimulation, unlike thalamotomy, selectively reduces tremor without altering sleep or sleep spindles. Our results also suggest that low frequency stimulation applied in the region of the reticular nuclei does not induce sleep.     

Deep Venous Thrombosis Prophylaxis After Unicompartmental Knee Arthroplasty: A Prospective Study on the Safety of Aspirin

Background

Although venous thromboembolism is one of the leading causes of morbidity after knee arthroplasty, little data exist on the risk of deep venous thrombosis (DVT) after unicompartmental knee arthroplasty (UKA).