电纺参数对PLGA/HA复合支架纤维形貌和直径的影响

目的通过静电纺丝的方法制备PLGA/HA复合支架,探讨电纺参数对复合支架纤维形貌和直径的影响。方法以三氯甲烷和N,N-二甲基甲酰胺为混合溶剂制备PLGA/HA纺丝液,通过调节PLGA的浓度、电压、接收距离,制备具有不同表面形貌的PLGA/HA复合纤维,采用SEM观察PLGA的浓度、电压、接收距离对纤维形貌和直径的影响。结果复合纤维的直径随PLGA浓度的增加而增加;随电压的增加而增加;随接收距离的增加先减小后增加。结论制备PLGA/HA复合支架较合适的电纺参数为：PLGA浓度25%,电压20KV,接收距离15cm。静电纺丝法制得的PLGA/HA复合支架有可能作为骨组织再生的支架在组织工程领域发挥作用。     

Mindfulness-based stress reduction: What processes are at work?

Mindfulness-Based Stress Reduction (MBSR) is a program that has been shown to be beneficial for clinical and non-clinical populations. While much attention has been paid to participants' outcomes, little work has been published concerning processes underlying improvements. Herein, women who had finished medical treatment for breast cancer completed questionnaires pre- and post-MBSR and were interviewed using focus group methodology such that quantitative and qualitative data were combined to explore potential mechanisms underlying changes. It was found that the Mindfulness Attention Awareness Scale was a useful process measure to assess changes in mindfulness and that the Coping with Health Injuries and Problems questionnaire was useful in documenting changes in palliative (self-care) coping over the course of the 8 week program. Moreover, the Sense of Coherence questionnaire suggested that the women viewed life as more meaningful and manageable following MSBR. Our findings fit with Shapiro et al.'s theory that, over time, participants in an MBSR program "reperceive" what they encounter in their daily experiences.     

三焦本质探源

三焦是中医学理论体系中非常重要的组成部分,但后世针对三焦的理论起源、结构部位、生理功能等诸多方面一直争议不断。三焦理论是基于五行脏腑理论而形成的,其本质为形而上理象化层次的功能之腑,有名无象,无具体解剖结构,其功能在于通行一身元气。     

中药“四气”概念的起源与嬗变

＂四气＂原本是气候术语,约西汉末被引进本草,借作为药物寒热理论的总称。北宋末寇宗奭认为＂气＂即香臭之气,倡言改＂四气＂为＂四性＂,但响应者稀。金元时＂四气＂概念发生嬗变,由药性寒热扩展为天气寒热,进而区分厚薄阴阳、升降浮沉,并与人体各脏腑产生对应关系。于是＂四气＂的作用从针对病因的寒热,扩大到针对不同的病位及脏腑发挥作用。明代医家曾尝试对嬗变后的＂四气＂理论进行条理与规范。用＂四气＂概括药性寒热理论是一个创举,无须更名。其含义在历代医疗实践中不断嬗变,以适应临床所需。     

新世纪初(2001-2012年)我国医学情报事业的发展

系统回顾了新世纪初期(2001-2012年)我国医学情报事业对人才培养、研究水平及合作情况、专业规范化及卫生政策的制定与卫生管理研究等方面的发展现状及存在的问题。这一时期医学情报事业呈现出高起点、高水平、高速度、高成效的迅猛发展势头。提出了争取顶层政策支持、加快人才培养与学科建设、开展理论与应用研究、加强机构间交流合作,为医学情报事业可持续发展的可借鉴对策。     

病理生理学五位一体综合理论教学法的探索

病理生理学在临床医学中具有重要作用,其理论性强的学科特点决定必需与临床密切结合才能学好病理生理学。五位体综合理论教学法的探索通过“理论教学一阶段案例分析-综合案例分析-医患互动-临床强化”等五个环节,对学生所学内容进行逐级强化,不仅使其对所学的每一个章节都能够及时理解和把握,而且能够彼此联系、融汇贯通,分析具体问题游刃有余,从而达到最佳的教学效果。     

What (or who) causes health inequalities: Theories,evidence and implications?

Health inequalities are the unjust differences in health between groups of people occupying different positions in society. Since the Black Report of 1980 there has been considerable effort to understand what causes them, so as to be able to identify actions to reduce them. This paper revisits and updates the proposed theories, evaluates the evidence in light of subsequent epidemiological research, and underlines the political and policy ramifications.     

A Complex Negotiation: Women's Experiences of Naming and Not Naming Premenstrual Distress in Couple Relationships

ABSTRACT

Recent research has demonstrated the importance of family relationships in women's experience of premenstrual changes, their construction of these changes as “PMS.” However, the discursive process by which women take up the subject position of “PMS” sufferer through the explicit naming of “PMS” to an intimate partner has received little research attention. Drawing on 60 individual interviews with Australian women, conducted between 2004 and 2006, we examined accounts of naming “PMS” in intimate relationships, women's explanations for naming or not naming, their experiences of their partner naming them as premenstrual. The analysis process identified an overarching theme of naming “PMS,” which was made up of three themes: naming to explain; “PMS” becoming the only explanation for distress; “PMS” as not a legitimate explanation for distress. The findings suggest that clinicians need to be aware of women's complex, often ambivalent, experiences of naming “PMS” within their relationships, when working with women, couples, seeking treatment or support for premenstrual distress.