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21.
Basilar skull fractures involving the temporal bone extend through the tympanic part of the temporal bone in two-thirds of cases. The anatomical relationship of this part of the temporal bone and the temporomandibular joint enables air to pass from the auditory canal into the joint. Air in the temporomandibular joint is demonstrated on CT scans as an indirect sign of temporal bone fracture. 相似文献
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目的 探讨与分析快速列车所致火车创伤中关节损伤的变化特点。方法 集1997~2000年火车提速后10214例火车创伤中1279例关节损伤病例,分析在特定条件下的致伤因素、损伤严重程度、损伤类型特点,经AIS-ISS评分证实与预后的关系。结果 提速后关节损伤发生率由提速前33.54%上升到34.12%,死亡率由28.88%上升到30.33%,多关节离断伤由19.84%上升到34.13%,开放性关节损伤由31.71%上升到63.65%,关节离断伤的死亡率由21.19%上升到49.07%。结论 火车创伤无疑是十分严重的损伤,多发伤率远高于其他损伤,治疗棘手,多器官功能不全综合征(MODS)是致死的主要因素。 相似文献
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Alex W Wilson Stephen J Medhurst Claire I Dixon Nick C Bontoft Lisa A Winyard Kim T Brackenborough Jorge De Alba Christopher J Clarke Martin J Gunthorpe Gareth A Hicks Chas Bountra Daniel S McQueen Iain P Chessell 《European Journal of Pain》2006,10(6):537-549
Clinically, inflammatory pain is far more persistent than that typically modelled pre-clinically, with the majority of animal models focussing on short-term effects of the inflammatory pain response. The large attrition rate of compounds in the clinic which show pre-clinical efficacy suggests the need for novel models of, or approaches to, chronic inflammatory pain if novel mechanisms are to make it to the market. A model in which a more chronic inflammatory hypersensitivity phenotype is profiled may allow for a more clinically predictive tool. The aims of these studies were to characterise and validate a chronic model of inflammatory pain. We have shown that injection of a large volume of adjuvant to the intra-articular space of the rat knee results in a prolonged inflammatory pain response, compared to the response in an acute adjuvant model. Additionally, this model also results in a hypersensitive state in the presence and absence of inflammation. A range of clinically effective analgesics demonstrate activity in this chronic model, including morphine (3mg/kg, t.i.d.), dexamethasone (1mg/kg, b.i.d.), ibuprofen (30mg/kg, t.i.d.), etoricoxib (5mg/kg, b.i.d.) and rofecoxib (0.3-10mg/kg, b.i.d.). A further aim was to exemplify the utility of this chronic model over the more acute intra-plantar adjuvant model using two novel therapeutic approaches; NR2B selective NMDA receptor antagonism and iNOS inhibition. Our data shows that different effects were observed with these therapies when comparing the acute model with the model of chronic inflammatory joint pain. These data suggest that the chronic model may be more relevant to identifying mechanisms for the treatment of chronic inflammatory pain states in the clinic. 相似文献
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Shinichiro Iwata Yasunori Suda Takeo Nagura Hideo Matsumoto Toshiro Otani Yoshiaki Toyama 《Knee surgery, sports traumatology, arthroscopy》2007,15(4):343-349
The purpose of this study is to evaluate the relationship between the magnitude of knee laxity and posterior instability at
different knee flexion angles and clinical disability in isolated posterior cruciate ligament (PCL) deficient patients. Knee
laxity at 20° and 70° of knee flexion were evaluated using KT-2000 arthrometer, and the posterior instability at 20°, 45°
and 90° of flexion were evaluated using stress radiography. We assessed the differences in the knee laxity and the tibial
translation between isolated PCL deficient knees and normal knees, and between the patients with giving-way during activities
of daily living (ADL) and without giving-way. There were statistical differences in the knee laxity and the tibial translation
at all knee flexion angles between the PCL deficient knees and normal knees. The magnitude of the knee laxity at 20° of flexion
measured with KT-2000 arthrometer was significantly larger in the patients with giving-way than those in the patients without
giving-way although there was no significant difference in the tibial translation at 70° between the two groups. The tibial
translation in both medial and lateral compartments at 20° and 45° measured with stress radiography were significantly larger
in the patients with giving-way than those in the patients without giving-way although there was not significant difference
at 90° between the two groups. These results suggested that the magnitude of the knee laxity and the posterior tibial translation
at shallow knee flexion angles would be related to giving-way during ADL in isolated PCL deficient patients. 相似文献
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Christopher A. Buneo Jyl Boline John F. Soechting Richard E. Poppele 《Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale》1995,104(3):467-479
We investigated, by using simulations, possible mechanisms responsible for the errors in the direction of arm movements exhibited by deafferented patients. Two aspects of altered feedforward control were evaluated: the inability to sense initial conditions and the degradation of an internal model. A simulation which assumed no compensation for variations in initial arm configuration failed to reproduce the characteristic pattern of errors. In contrast, a simulation that assumed random variability in the generation of joint torque resulted in a distribution of handpaths which resembled some aspects of the pattern of errors exhibited by deafferented patients. 相似文献
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人工全髋关节置换术中偏心距重建对髋关节功能的影响 总被引:2,自引:0,他引:2
目的比较标准股骨假体行人工全髋关节置换术中股骨假体颈长和股骨距保留对偏心距重建的作用,并分析偏心距重建对软组织平衡的影响。方法68例(71髋)行初次全髋关节置换术并获得随访。术中确定双下肢等长、髋关节稳定及周围软组织紧张度适中。术后采用Harris评分评估手术结果,Cybex-6000等速测定患髋外展肌力,通过手术记录和X线片测量获得偏心距、股骨距、假体颈长、外展肌力臂,用SPSS11.5统计学软件包对数据进行分析。结果假体颈长对偏心距的影响较股骨距大(P<0.01),并与偏心距呈正相关关系(r=0.642,P<0.001),但两者对于Harris评分影响的差异无统计学意义(P〉0.05)。股骨头坏死患者术后的偏心距较髋关节骨关节炎患者(P<0.01)和股骨颈骨折患者小(P<0.01)。颈于角与偏心距外展肌力臂比呈正相关关系(r=0.25,火0.05)。偏心距重建较好的髋关节术后外展肌力较偏心距重建不足者优(P<0.05),且两者呈相关关系(r=0.29,P<0.05)。结论偏心距的重建在全髋关节置换术软组织平衡中主要起到增强术后外展肌力的作用。采用标准股骨假体重建术后股骨偏心距,股骨假体颈长对人工全髋关节置换术后偏心距的重建作用大于股骨距的保留,在诸多影响因素中起到关键作用。 相似文献