全文获取类型
收费全文 | 686篇 |
免费 | 28篇 |
国内免费 | 11篇 |
专业分类
耳鼻咽喉 | 23篇 |
儿科学 | 11篇 |
妇产科学 | 13篇 |
基础医学 | 34篇 |
口腔科学 | 14篇 |
临床医学 | 84篇 |
内科学 | 181篇 |
皮肤病学 | 2篇 |
神经病学 | 20篇 |
特种医学 | 24篇 |
外科学 | 91篇 |
综合类 | 34篇 |
预防医学 | 142篇 |
眼科学 | 6篇 |
药学 | 33篇 |
中国医学 | 9篇 |
肿瘤学 | 4篇 |
出版年
2024年 | 3篇 |
2023年 | 24篇 |
2022年 | 37篇 |
2021年 | 39篇 |
2020年 | 25篇 |
2019年 | 41篇 |
2018年 | 35篇 |
2017年 | 21篇 |
2016年 | 21篇 |
2015年 | 21篇 |
2014年 | 67篇 |
2013年 | 50篇 |
2012年 | 26篇 |
2011年 | 31篇 |
2010年 | 37篇 |
2009年 | 39篇 |
2008年 | 39篇 |
2007年 | 42篇 |
2006年 | 28篇 |
2005年 | 27篇 |
2004年 | 11篇 |
2003年 | 8篇 |
2002年 | 7篇 |
2001年 | 6篇 |
2000年 | 5篇 |
1999年 | 3篇 |
1998年 | 6篇 |
1997年 | 4篇 |
1996年 | 1篇 |
1995年 | 4篇 |
1994年 | 2篇 |
1993年 | 1篇 |
1992年 | 1篇 |
1988年 | 2篇 |
1986年 | 4篇 |
1982年 | 1篇 |
1980年 | 1篇 |
1979年 | 1篇 |
1976年 | 1篇 |
1973年 | 1篇 |
1972年 | 1篇 |
1971年 | 1篇 |
排序方式: 共有725条查询结果,搜索用时 0 毫秒
31.
《Radiologia》2019,61(6):510-513
We present a case of a female patient with ovarian cancer who had an inadvertent vascular access device implantation in the subclavian artery, being detected after 10 days. She was successfully treated with a covered stent without immediate complications. 相似文献
32.
33.
34.
Patent foramen ovale (PFO) percutaneous closure has previously been an accepted intervention for the prevention of recurrent cryptogenic stroke on the basis of observational studies. However, randomized trials have been lacking until now. Three recently published randomized trials (CLOSURE I, PC and RESPECT) do not demonstrate the superiority of this intervention versus optimal medical therapy, therefore making this practice questionable. Nonetheless, these trials have had certain pitfalls, mainly a lower than initially estimated number of patients recruited, therefore lacking sufficient statistical power. On the other hand, different closure devices were used in the three trials. In two of them (PC and RESPECT), the Amplatzer PFO Occluder was used and the STARflex device was used in the other one (CLOSURE I). Taken altogether, a meta-analysis of these three trials does not demonstrate a statistically significant benefit of percutaneous PFO closure (1.9% vs 2.9%; P = 0.11). However, if we analyze only the PC and RESPECT trials together, in which the Amplatzer PFO Occluder was used, a statistically significant benefit of percutaneous PFO closure is observed (1.4% vs 3.0%, P = 0.04). In conclusion, our interpretation of these trials is that the use of a dedicated, specifically designed Amplatzer PFO device could possibly reduce the risk of stroke in patients with PFO and cryptogenic stroke. This consideration equally applies to patients who have no contraindications for anticoagulant or antithrombotic therapy. 相似文献
35.
《Journal of neuroradiology. Journal de neuroradiologie》2020,47(4):301-305
Background and purposeThe NeVa™ (Vesalio, Nashville, Tennessee) thrombectomy device is a CE-approved novel hybrid-cell stent retriever with offset enlarged openings coupled with functional zones and a closed distal end. The device was designed to incorporate and trap resistant emboli. The purpose was to determine the safety and efficacy of the NeVa™ stent.MethodsProspective data was collected on the first thirty consecutive patients treated at four stroke centers with NeVa™ as first line treatment between December 2017 and May 2018. Clinical outcome measures included re-perfusion scores after each pass, complications (per-procedural complications, device related adverse events, all intracerebral hemorrhage (ICH) and symptomatic ICH (sICH) on follow up imaging), 24 hour NIHSS, mRS at discharge and 90 days. Baseline data as well as treatment parameters were documented.ResultsMean presenting NIHSS was 16. Sites of primary occlusion were 10 ICA, 16 M1-MCA, 3 M2-MCA and one basilar. There were five tandem occlusions. Reperfusion outcomes after each NeVa pass; TICI ≥ 2b after first pass 63%, after 1 or 2 passes 83%, after 1 to 3 passes 90%. TICI 2c-3 after first pass 47%, after 1-2 passes 57%, after 1–3 passes 60%. TICI ≥ 2b after final pass 93%; TICI 2c-3, 63%. There were no device related serious averse events and no sICH. Clot material was partially or completely incorporated into the device after 70% passes. The mean 24 hour NIHSS was 7 and the 90 day mRS was 0–2 in 53%.ConclusionsThe NeVa™ device demonstrated a high rate of first pass complete reperfusion effect, a good safety profile and favorable 90 day clinical outcomes in this initial clinical experience. 相似文献
36.
Steven A. Rooker Krishna S. Vyas Emma C. DiFilippo Ian T. Nolan Shane D. Morrison Richard A. Santucci 《The journal of sexual medicine》2019,16(5):661-672
Background
Penile prostheses are commonly used to achieve erectile rigidity after phalloplasty in trans masculine patients. Implantation poses significant challenges because of the delicate nature of the neophallus and lack of native erectile tissue. Many groups have developed novel phalloplasty and prosthesis insertion techniques, but none have proven superior.Aim
To analyze and aggregate reported characteristics and outcomes of penile prosthesis implantation in the trans masculine patient.Methods
A comprehensive literature search of Medline, EMBASE, and Cochrane Registry databases was conducted for studies published through February 19, 2019, with multiple search terms related to penile prosthesis use in gender-affirming surgical procedures.Outcomes
Studies were included and tabulated if they reported prosthesis outcomes in patients who received a neophallus as part of a gender-affirming procedure.Results
23 journal articles met inclusion criteria from 434 references identified. All selected articles were either retrospective or case series/reports. A total of 1,056 patients underwent phalloplasty, and 792 received a penile prosthesis. Most (83.6%) of the prostheses were inflatable, whereas 16.4% were non-inflatable. The number of cylinders used for each prosthesis was 61.0% single-cylinder and 39.0% double-cylinder. The mean follow-up duration was 3.0 years. Of patients who received a prosthesis, 36.2% reported a prosthesis complication; at follow-up 60.0% of patients had their original implant present, and 83.9% reported achieving penetration.Clinical Implications
Prosthesis implantation in gender-affirming operations poses significant risk of complication, but it is still a reasonable and useful method to achieve rigidity necessary for sexual intercourse.Strength & Limitation
This is the first study to aggregate all reported penile prosthesis characteristics and outcomes in trans masculine patients. This study was significantly limited by inconsistent reporting of demographics, sensation, urinary health, patient satisfaction, and penetrative sex. The lack of comparative studies precluded any meaningful meta-analytical comparison.Conclusions
There is a great need for a prosthesis designed to meet the specific needs of the trans masculine patient after phalloplasty. Standardized methods of reporting implant outcomes including sexual function, sensation, and patient satisfaction should be refined for future studies. This study can assist patients and surgeons about the risks and benefits of this procedure.Rooker SA, Vyas KS, DiFilippo EC, et al. The Rise of the Neophallus: A Systematic Review of Penile Prosthetic Outcomes and Complications in Gender-Affirming Surgery. J Sex Med 2019;16:661–672. 相似文献37.
I. C. T. Santos J. G. Mendes M. P. F. Paulo 《Journal of medical engineering & technology》2013,37(6):437-441
In dental medicine, the study of mandibular movement has an important role in oral rehabilitation as it allows diagnosis of pathologies in the temporomandibular joint and the definition of adequate treatment plans. In this paper, a new device specially developed for the acquisition and analysis of 3D mandibular movement is presented. A facial arc is adopted as its main support structure and electromagnetic sensors are employed to acquire the mandibular movement. A neural network is used to transform the electrical signals output by the sensors into 3D Cartesian coordinates. A custom-made computer application is developed to display and analyse the movement acquired. The device is shown to be easy to use, comfortable for patients and capable of being produced at an affordable price. 相似文献
38.
为适应全国医疗器械检验机构日渐复杂的工作流程,为使医疗器械检验工作更加科学化、规范化,同时做到可查、可追,我们设计了此软件。目前,在国家食品药品监督管理局沈阳医疗器械质量监督检验中心实施执行此软件,它改变了检验工作档案记录没有数字化图像的历史,对于现场检验,避免漏检、错检起到了决定性的改变,实现了实时资料审查,及时修正错误。 相似文献
39.
40.
通过介绍国际医疗器械法规协调组织发起的,在国际范围内交换医疗器械不良事件监测信息的国家医疗器械管理机构报告,旨在为我国开展医疗器械不良事件监测信息管理及参与国际信息交流提供借鉴。 相似文献