全文获取类型
收费全文 | 55958篇 |
免费 | 4641篇 |
国内免费 | 1260篇 |
专业分类
耳鼻咽喉 | 826篇 |
儿科学 | 500篇 |
妇产科学 | 161篇 |
基础医学 | 2063篇 |
口腔科学 | 2346篇 |
临床医学 | 8802篇 |
内科学 | 6332篇 |
皮肤病学 | 191篇 |
神经病学 | 2953篇 |
特种医学 | 17918篇 |
外国民族医学 | 27篇 |
外科学 | 4914篇 |
综合类 | 6178篇 |
现状与发展 | 4篇 |
预防医学 | 864篇 |
眼科学 | 3190篇 |
药学 | 1405篇 |
9篇 | |
中国医学 | 156篇 |
肿瘤学 | 3020篇 |
出版年
2024年 | 173篇 |
2023年 | 1139篇 |
2022年 | 2017篇 |
2021年 | 2633篇 |
2020年 | 2086篇 |
2019年 | 1843篇 |
2018年 | 1893篇 |
2017年 | 1781篇 |
2016年 | 1901篇 |
2015年 | 1912篇 |
2014年 | 3752篇 |
2013年 | 2993篇 |
2012年 | 3314篇 |
2011年 | 3551篇 |
2010年 | 3122篇 |
2009年 | 3224篇 |
2008年 | 3142篇 |
2007年 | 3164篇 |
2006年 | 2827篇 |
2005年 | 2397篇 |
2004年 | 1945篇 |
2003年 | 1614篇 |
2002年 | 1321篇 |
2001年 | 1189篇 |
2000年 | 936篇 |
1999年 | 803篇 |
1998年 | 634篇 |
1997年 | 651篇 |
1996年 | 509篇 |
1995年 | 468篇 |
1994年 | 417篇 |
1993年 | 304篇 |
1992年 | 245篇 |
1991年 | 207篇 |
1990年 | 195篇 |
1989年 | 190篇 |
1988年 | 164篇 |
1987年 | 177篇 |
1986年 | 125篇 |
1985年 | 155篇 |
1984年 | 161篇 |
1983年 | 94篇 |
1982年 | 140篇 |
1981年 | 114篇 |
1980年 | 78篇 |
1979年 | 61篇 |
1978年 | 34篇 |
1977年 | 39篇 |
1976年 | 23篇 |
1974年 | 1篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
51.
Matthew D. Li Katrina F. Chu Allegra DePietro Vincent Wu Eric Wehrenberg-Klee Omar Zurkiya Raymond W. Liu Suvranu Ganguli 《Journal of vascular and interventional radiology : JVIR》2019,30(3):314-319
Purpose
To evaluate the feasibility of a same-day yttrium-90 (90Y) radioembolization protocol with resin microspheres (including pretreatment angiography, lung shunt fraction [LSF] determination, and radioembolization) for the treatment of hepatocellular carcinoma (HCC) and liver metastases.Materials and Methods
All same-day radioembolization procedures performed over 1 y (February 2017 to January 2018) were included in this single-institutional retrospective analysis, in which 34 procedures were performed in 26 patients (median age, 63 y; 13 women), 19 with liver metastases and 7 with HCC. Yttrium-90 treatment activities were calculated by body surface area method. Tumor imaging response was assessed by Response Evaluation Criteria In Solid Tumors (RECIST) 1.1 for liver metastases and modified RECIST for HCC. Clinical side effects and adverse events were graded per Common Terminology Criteria for Adverse Events version 4.0.Results
All planned cases were technically successful, and no cases were canceled for elevated LSF or vascular anatomic reasons. Pretreatment angiography modified the planned 90Y treatment activity in 1 case in which vascular anatomy required a lobar-dose split into 2 for segmental infusions. In 18% of cases, patients were briefly admitted after the procedure for observation or symptom management. Imaging evaluation of initial efficacy at 1 month demonstrated partial response in 25% and stable disease in 67% of patients with liver metastases and partial/complete response in 43% and stable disease in 14% of patients with HCC. Grade ≥ 3 adverse events occurred in 6% of cases, with no systemic therapy–limiting toxicities. The mean total procedure time was 4.2 hours.Conclusions
A same-day 90Y radioembolization protocol with resin microspheres is feasible in select patients, which can expedite cancer therapy. 相似文献52.
53.
Xiaoxuan Liu Ameenat L. Solebo Livia Faes Sophie Beese Tasanee Braithwaite Matthew E. Round 《Ocular immunology and inflammation》2020,28(6):898-907
ABSTRACT
Purpose
New instrument-based techniques for anterior chamber (AC) cell counting can offer automation and objectivity above clinician assessment. This review aims to identify such instruments and its correlation with clinician estimates. 相似文献54.
55.
56.
段前深 《实用医学影像杂志》2020,(2):127-129
目的探讨CT扫描在胸膜外孤立性纤维瘤(E-SFT)中的诊断价值。方法回顾性分析2015年4月至2018年4月于我院接受手术治疗的90例E-SFT患者术前CT检查影像资料和术后病理、免疫组织化学资料,评估CT检查在E-SFT诊断中的应用价值。结果 90例E-SFT患者均为单发肿瘤,免疫组织化学及病理学检查示良性80例,恶性10例;CT检查结果为良性72例,平扫表现为圆形或类圆形软组织密度影,密度不均匀,大部分边缘清晰,增强扫描表现为均匀强化;恶性18例,平扫示肿瘤体积较大,边界不清,密度不均,可见大片不规则低密度区,增强扫描瘤体强化不均匀,低密度区无明显强化;CT诊断的敏感度、准确度、特异性阳性率、阴性率分别为60%(6/10)、82%(74/90)、85%(68/80)、33%(6/18)、94%(68/72)。结论 E-SFT的CT检查影像图像具有一定的特征性,尤其是增强扫描有助于评估纤维瘤的良恶性,可将其作为术前诊断及术后复查评估的有效依据用于临床诊疗工作中。 相似文献
57.
Background:Colon cancer is a common malignant tumor of the gastrointestinal tract. Therefore, a clear diagnosis is particularly important for the treatment of colon cancer. Ultrasound and spiral computed tomography (CT) can both be used in the diagnosis, but each has its own advantages and disadvantages, which could cause confusion in clinical choice. The purpose of this study was to systematically evaluate the practicability of spiral CT and ultrasound in the diagnosis of colon cancer.Methods:A systematic search was performed by retrieving on English databases (PubMed, Embase, Web of Science, the Cochrane Library) and Chinese databases (CNKI, Wanfang, Weipu [VIP], CBM). Besides, manually search for Google and Baidu academic of diagnostic experimental study of ultrasound and spiral CT in the diagnosis of Colon Cancer. The retrieval time limit was from the establishment of the database to October 2020. Two researchers independently extracted and evaluated the quality of the data in the included study. A meta-analysis was performed using Meta Disc1.4 and RevMan5.3 software.Results:Sensitivity, specificity, positive Likelihood ratio, negative likelihood ratio, and diagnostic odds ratio were used to determine the diagnostic efficacy of ultrasonography and helical CT in colorectal cancer.Conclusions:This study will compare the practicability of CT and ultrasound in the diagnosis of colon cancer and provide reliable evidence-based basis for clinicians to choose the appropriate or best evidence-based basis.Ethics and dissemination:The private information from individuals will not be published. This systematic review also will not involve endangering participant rights. Ethical approval is not required. The results may be published in a peer-reviewed journal or disseminated in relevant conferences.OSF Registration number:DOI 10.17605/OSF.IO/WAJHQ 相似文献
58.
《Journal of infection and chemotherapy》2019,25(6):470-472
We herein report a case of Klebsiella pneumoniae (K. pneumoniae) spondylitis and bacteremia in a 90-year-old man with diabetes mellitus who had undergone sigmoidectomy and had a fecalith. Two months prior to admission, he had received antimicrobial treatment for 2 weeks for K. pneumoniae bacteremia whose entry was unclear and he was readmitted to our hospital owing to fever and stomachache. K. pneumoniae was isolated from two sets of blood cultures, and computed tomography and magnetic resonance imaging revealed inflammation and destruction of the 8th and 9th thoracic vertebra. The diagnosis was spondylodiscitis secondary to K. pneumoniae bacteremia. Although the entry point for K. pneumoniae was unclear, we suggest that inflammation of the mucosa around the fecalith might have caused the Enterobacteriaceae bacteremia. 相似文献
59.
60.
《Journal of Clinical Orthopaedics and Trauma》2019,10(2):380-386
Additive manufacturing is a rapidly emerging technology which is being successfully implemented in the various field of medicine as well as in orthopaedics, where it has applications in reducing cartilage defects and treatments of bones. The technology helps through systematic collection of information about the shape of the "defects" and precise fabrication of complex 3D constructs such as cartilage, heart valve, trachea, myocardial bone tissue and blood vessels. In this paper, a large number of the relevant research papers on the additive manufacturing and its application in medical specifically orthopaedics are identified through Scopus had been studied using Bibliometric analysis and application analysis is undertaken. The bibliometric analysis shows that there is an increasing trend in the research reports on additive manufacturing applications in the field of orthopaedics. Discussions are on using technological advancement like scanning techniques and various challenges of the orthopaedic being met by additive manufacturing technology. For patient-specific orthopaedic applications, these techniques incorporate clinical practice and use for effective planning. 3D printed models printed by this technology are accepted for orthopaedic surgery such as revision of lumbar discectomy, pelvic surgery and large scapular osteochondroma. The applications of additive manufacturing in orthopaedics will experience a rapid translation in future. An orthopaedic surgeon can convert need/idea into a reality by using computer-aided design (CAD) software, analysis software to facilitate the manufacturing. Thus, AM provides a comprehensive opportunity to manufacture orthopaedic implantable medical devices. 相似文献