Once-monthly radiotherapy for the palliation of pelvic gynecological malignancy

Twenty-seven patients with advanced pelvic gynecological malignancies were treated using a once-monthly fractionation scheme of 10 Gy to a total dose of 30 Gy to the whole pelvis. This course was well tolerated and provided effective palliation with a minimum of hospitalization. The results obtained suggest this course merits consideration for the palliation of other pelvic malignancies.     

Plasma melatonin, pinealocyte morphology, and surface receptors/antigen expression on macrophages/microglia in the pineal gland following a high-altitude exposure

The present study examined the effects of high-altitude exposure on the pineal gland, the main source of production of melatonin. It was surmised that hypoxia experienced at high altitude, caused by decreased oxygen tension in the ambient air, might lead to some structural alterations in the pineal gland and, hence, affect its melatonin production. Adult Wistar rats were exposed to an altitude of 8,000 m for 2 hr in an altitude chamber and then sacrificed at various time intervals after the exposure. Normal rats kept at ground level were used as controls. Blood samples were collected at various time intervals for measurement of plasma melatonin level, and the pineal glands from both groups were processed for electron microscopy and immunohistochemistry. The plasma melatonin level showed a steady increase following altitude exposure peaking at 7 days and returned to control levels thereafter. Between 1 and 4 days after altitude exposure, the mitochondrial number and lipid droplets in the pinealocytes appeared to be reduced compared with those in control rats. At 7 days, however, the mitochondrial numbers and lipid droplets were noticeably increased. At the same time interval, the expression of complement type 3 receptors and major histocompatibility class II antigens as detected with the antibodies OX-42 and OX-6, respectively, in macrophages/microglia was up-regulated compared with that in the control rats and those killed at earlier times. This was attributed to the increased serum melatonin after the altitude exposure. By 14 and 21 days, the ultrastructure of pinealocytes and immunoreactivity of macrophages/microglia were comparable with those in the control rats. We conclude from this study that an altitude exposure in rats leads to an increase in melatonin production, which returned to control levels with passage of time.     

合理选配CR和DR

数字化放射科是现代化医院建设中重要的组成部分，合理选配CR和DR符合当今医疗发展的需求。对CR和DR的配置构成提出见解，并对设备的基本技术条件进行分析，希望能给予医院筹备及改造发展放射科有一定帮助。     

探讨CR900系统中伪影的处理方法

目的 探讨CR900系统工作中图像的稳定性，尽量避免各种操作不当产生的伪影。方法 随机抽取CR图像1000张，分析其中伪影的产生原因。结果 经过分析将伪影产生的原因，针对性的制定相应的防止与处理方法，提高了图像质量，增加合格率，降低废片率。结论 CR系统是较为复杂的工作过程，把握每一个工作环节对获得良好的影像质量非常重要。     

颈椎张口位数字摄影与常规X线摄影应用比较

目的:比较传统屏胶系统与CR(computed radiography)、DDR(direct digital radiography)摄影技术在颈椎张口位投照中的优缺点。方法:通过投照次数、照片质量、所需时间在各种摄影方式中的差别来进行比较。结果:3种摄影方法,DDR摄影技术优势明显。结论:直接数字化摄影的发展前景更为广阔。     

准高KV技术床边胸部CR摄影的应用体会——附120例胸片分析

目的 探讨准高KV摄影技术对床边胸部CR摄影的一临床应用价值。方法 采用西门子250mA床边X线机，Kodak Oirectview CR system 900型和配套14＋17英寸IP板，对120例准高KV摄影床边胸部CR影像质量及病变显示特点进行分析。另取120例普通KV床边胸片对照分析，统计分析采用配对样本秩和检验方法。结果 120例准高KV床边胸片甲级片102例（占85．0％），乙级片11例（占9．2％），丙级片7例（5．8％），无厦片。与普通KV组差异有统计学意义（Z=-3．939，P=0．00069）。结论 准高KV摄影技术能明显提高床边胸部cR影像甲片率，减低病人的辐射量，提高床边X线机的使用范围，为疾病诊断提供更多的影像信息。     

趋化因子受体CX3CR1基因多态性与缺血性脑血管病的关系

缺血性脑血管病最重要的病理生理基础是颅内血管的动脉粥样硬化。CX3CRl两个单核苷酸多态性T280M、V249I在动脉粥样硬化中已有报道，这个位点的遗传变异可能影响缺血性脑血管病的遗传易感性。     

CR钼靶与彩色多普勒超声对乳腺结节诊断的临床应用研究

目的:评价CR钼靶与彩色多普勒超声(color Doppler ultrasonography,CDUS)对乳腺结节诊断的临床应用价值。方法:对126例经CR钼靶、CDUS检查的乳腺结节资料进行分析比较,并与术后病理结果对照。结果:126例乳腺结节有76例良性病变,CR钼靶诊断正确66例,CDUS诊断正确68例(χ2=0.07,P>0.05),CR钼靶+CDUS诊断正确71例。有50例恶性病变,CR钼靶诊断正确46例,超声诊断正确36例(χ2=3.87,P<0.05),CR钼靶+CDUS诊断正确49例。结论:在乳腺结节良性病变诊断中,CR钼靶与CDUS无明显统计学差异,但对乳腺恶性肿块的检出,CR钼靶较CDUS有明显优势,二者联合诊断乳腺疾病的准确率高于两种方法单独使用,在乳腺疾病的检查中可以发挥优势互补的作用。     

计算机X线摄影系统在颈部疾病诊断中的应用价值

目的:探讨计算机X线摄影(CR)系统在颈部疾病诊断中的应用价值。方法::对100例颈部疾病患者用KODAK850型CR在调节对比、边缘对比、宽容度减少、噪音减小、窗位增宽左及窗位增宽右等参数做了图像后处理与常规的屏/片系统比较。结果:100例颈部CR系统的检查均获得满意照片:颈部骨骼及软组织同时很好地显示出来。结论:CR在颈部疾病特别是在软组织病变的诊断上有良好效果。     

计算机放射系统（CR）图像的特点

探讨计算机放射系统(CR)图像的特点。通过对我院一年的CR图像质量进行分析,并与传统屏-片系统在技术操作、图像质量控制与后处理技术等各方面进行比较。说明计算机放射成像系统(CR)以其高灰阶分辨率、强大的计算机图像后处理功能、小辐射剂量等优势,己成为医学成像技术新的热点。