全文获取类型
收费全文 | 28104篇 |
免费 | 2047篇 |
国内免费 | 852篇 |
专业分类
耳鼻咽喉 | 122篇 |
儿科学 | 598篇 |
妇产科学 | 419篇 |
基础医学 | 1286篇 |
口腔科学 | 772篇 |
临床医学 | 3201篇 |
内科学 | 8569篇 |
皮肤病学 | 112篇 |
神经病学 | 1136篇 |
特种医学 | 1604篇 |
外科学 | 5690篇 |
综合类 | 3334篇 |
现状与发展 | 1篇 |
预防医学 | 676篇 |
眼科学 | 1266篇 |
药学 | 1349篇 |
13篇 | |
中国医学 | 586篇 |
肿瘤学 | 269篇 |
出版年
2024年 | 65篇 |
2023年 | 653篇 |
2022年 | 1110篇 |
2021年 | 1652篇 |
2020年 | 1488篇 |
2019年 | 1485篇 |
2018年 | 1372篇 |
2017年 | 991篇 |
2016年 | 945篇 |
2015年 | 1090篇 |
2014年 | 1970篇 |
2013年 | 1953篇 |
2012年 | 1382篇 |
2011年 | 1564篇 |
2010年 | 1299篇 |
2009年 | 1234篇 |
2008年 | 1188篇 |
2007年 | 1115篇 |
2006年 | 1009篇 |
2005年 | 839篇 |
2004年 | 699篇 |
2003年 | 653篇 |
2002年 | 575篇 |
2001年 | 509篇 |
2000年 | 369篇 |
1999年 | 362篇 |
1998年 | 387篇 |
1997年 | 341篇 |
1996年 | 323篇 |
1995年 | 252篇 |
1994年 | 257篇 |
1993年 | 245篇 |
1992年 | 193篇 |
1991年 | 167篇 |
1990年 | 134篇 |
1989年 | 134篇 |
1988年 | 107篇 |
1987年 | 97篇 |
1986年 | 96篇 |
1985年 | 110篇 |
1984年 | 100篇 |
1983年 | 69篇 |
1982年 | 79篇 |
1981年 | 73篇 |
1980年 | 63篇 |
1979年 | 43篇 |
1978年 | 57篇 |
1977年 | 26篇 |
1976年 | 29篇 |
1975年 | 14篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
21.
应用同种动脉治疗主动脉根部病变 总被引:4,自引:0,他引:4
报告5例采用同种动脉(HAV)治疗5例主动脉根部病变(主动脉瓣狭窄1例,关闭不全4例)。男3例,女2例;年龄13~47岁。病因为细菌性心内膜炎2例(包括先天主动脉瓣二瓣化畸型1例),Marfan综合征2例,风湿性主动脉瓣关闭不全1例。术中采用同种主动脉全根置换3例(Bentall手术),其中1例用HAV上的二尖瓣前叶加宽主动脉瓣环(Manouguian手术),余2例用自体肺动脉移置主动脉根部,另取同种肺动脉做原位移置(Ross手术)。结果死亡1冽,4例存活,且无并发症发生。术后超声心动图提示主动脉根部良好,无主动脉瓣反流。随访2.5~3.5年疗效满意。 相似文献
22.
Yaping Deng huashang Zhou Junguo DuanDepartment of Ophthalmology the Teaching Hospital of Chengdu College of TCM Chengdu China 《眼科学报》1994,(1)
Twenty five cases, including 26 eyes with retinal vein occlusion (RVO) were examined by means of the electro-oculogram. The results showed that 23 of the 26 eyes suffering from RVO exhibited abnormalities of the electro-oculogram (EOG). The potential difference and Arden ratio in the RVO eyes were lower than those in the normal eyes (P<0.01). The more the visual acuity of ill eyes was decreased, the higher the abnormal rate of EOG in ill eyes was. 14 eyes had the visual acuity less than 0.1, whose EOGs were abnortmal. Six eyes had the visual acuity from 0. 2 to 0. 4, in which the EOGs of 5 eyes were abnormal. Six eyes had the visual acuity more than 0. 5, a-mong which the EOGs of 4 eyes were abnormal. Based on the above observations, it may be considered that the circulatory disturbance resulting from RVO damages not only the internal layer but also the external layer of the retina. We suggest that EOG is a useful method for distingquishing lesions caused by RVO and may reflect the functional condition 相似文献
23.
报告应闭合式玻璃体切除术治疗7例(7眼)因视网膜静脉阻塞所致的玻璃体出血。所有病人术后眼底清晰可见,视力明显提高。术后4例出现再出血,经药物治疗后出血吸收,加用氩离子激光视网膜光凝,无再出血。随访3至18个月所有病人无新生血管性青光眼及牵引性视网膜脱离出现。认为玻璃体切除术不但能使屈光间质恢复透明,视力提高,预防牵引性视网膜脱离,而且为明确诊断和进一步激光治疗提供条件。 相似文献
24.
贲门失驰缓症介入治疗的疗效评价 总被引:1,自引:0,他引:1
目的:评价贲门失弛缓症球囊扩张介入治疗的疗效。方法:对20例贲门失驰缓症患者行球囊扩张术。结果:20例患者共进行了31次球囊扩张,人均1.5次(其中12例扩张1次,5例扩张2次,3例扩张3次)。术后患者吞咽困难明显缓解,主要并发症为疼痛和返流。术后随访无症状期为3-13个月。结论:球囊扩张术是治疗门失弛缓症的有效方法。 相似文献
25.
Abstract: This paper dicusses the use of esophageal dilatation with a Rigiflex TTS balloon. This method was used 45 times on 11 patients affected by anastomotic or a severe grade peptic esophageal stenosis. Fluoroscopic guidance was used in 36 procedures (80%) without effecting the mean duration of the treatment (12 minutes). The results were considered satisfactory when these goals had been achieved: a) dilatation of the stenosis over 15 mm; b) a dysphagia free-time of more than 6 months. A satisfactory result was achieved in 10 patients (90.9%), without deaths and major complications. 5 patients received 1 dilatation and the other 5 needed, 3-3-4-7–11 procedures respectively to obtain a satisfactory result. On these basis we consider that its great efficacy, security and tolerability depend on the following characteristics of the Rigiflex TTS balloon: 1) “radial” dilatation; 2) the possibility of introducing the balloon through the operative channel of the fiberscope; 3) direct visualization of the stenosis during dilatation. The following disadvantages with this method are: the absence of a tactile sensation of dilatation and the elevated cost of the instrument. We conclude that the Rigiflex TTS balloon is an important alternative to guide-wire techniques, especially for the treatment of severe esophageal strictures. 相似文献
26.
Albert B. Zajko M.D. Klaus M. Bron William L. Campbell 《Cardiovascular and interventional radiology》1987,10(1):28-31
Biliary obstruction and multiple hepatic abscesses occurred in a patient after ligation of a segmental branch of the right
hepatic duct. The patient was successfully managed by transhepatic biliary drainage and balloon dilatation of an internal
fistula that developed between the ligated duct and a Roux limb of jejunum. Internal biliary fistulas may be dilated using
interventioanl radiologic techniques to permit nonobstructed bile flow. Implications for the nonsurgical treatment' of biliary
strictures are discussed. 相似文献
27.
C Vassanelli G Menegatti B Silverstein P Zardini R Cubeddu V Russo O Svelto 《Lasers in surgery and medicine》1987,7(1):23-28
Percutaneous transluminal balloon angioplasty (PTA) is being currently used in patients with coronary artery disease. Laser irradiation (LI) has been effective in vaporizing atherosclerotic plaques. The purpose of this work was twofold: to compare PTA and LI techniques in the recanalization of experimental obstructive arterial lesions, and to evaluate the possibility of reducing the failures and local complications and increasing the success rate of PTA by the combined use of LI. Atherosclerotic iliac stenoses were induced in 27 rabbits; lesions were evaluated angiographically before and after intervention and were studied histologically and by electron microscopy. Argon-ion LI delivered through microlens-tip optic fibers reduced the stenotic area from 64.2 +/- 21.8% to 40.3 +/- 10.7% (n = 10, P less than .01) and PTA from 60.7 +/- 15.9% to 30.4 +/- 7.7% (n = 9, P less than .01). However, percentage reduction was higher in PTA-treated stenoses (48.4 +/- 10.1% vs 34.5 +/- 13.5%, P less than .0125). In eight more rabbits, low power LI (4.55 +/- 1.25 J) was delivered after PTA in dilated segments. Post-PTA LI further decreased stenoses (from 31.2 +/- 7.8% to 29.1 +/- 8.1%, P less than .0125); laser-irradiated segments showed diffuse carbonization of the disrupted intimal layer. The normalized transtenotic pressure gradient decreased significantly in all groups: LI reduced the gradient from .40 +/- .25 to .17 +/- .07 (P = .005); PTA from .37 +/- .14 to .11 +/- .04 (P = .001); LI after PTA from .40 +/- .16 to .12 +/- .06 (P = .001). Thus, LI is effective (less than PTA) in relieving experimental atherosclerotic stenoses and seems useful when combined with PTA. 相似文献
28.
Summary Bronchus stump insufficiency following lung resection, with an average incidence of 4%, is a serious complication which carries a mortality of up to 90%. Operative transthoracic approaches have been largely unsatisfactory because of the high operative risk and rapidly spreading infection. In an experimental study on 18 pigs, endoscopic occlusion of infected bronchus stump fistulae was achieved with fibrin sealant (1 ml, 500 units/ml thrombin, 3500 units/ml aprotinin) applied via a flexible bronchoscope. During autopsy, all bronchus stump fistulae were found to have healed after the second postoperative week. Transitory local abscesses of the pleura could be prevented by high-dose systemic antibiotic therapy for 5 postoperative days but not by antibiotics added to the fibrin sealant. This endoscopic method has already been performed successfully in 3 clinical cases; additional sclerotherapy with (2–3 ml Ethoxysclerol applied around the fistula orifice was carried out before fibrin sealing to stimulate fibrosis. Endoscopic controls demonstrated fistula closure by granulation tissue after 2 weeks. This procedure could become the method of choice for infected postoperative fistulae of the bronchus stump and should be attempted in any case before operative approaches are considered. 相似文献
29.
目的探讨腹茧症合并不孕的病因和诊治方法。方法对1996年至2005年因不孕施行腹部手术中发现的7例腹茧症患者进行回顾性分析。结果7例患者均为原发、管性不孕。其共同特点为,术中见多重疏松、灰白色的纤维膜状组织包裹于肠管间隙及盆腔脏器,手术分离困难。结论腹茧症引起的不孕可能为纤维膜包裹输卵管,使其丧失活动度,伞端封闭,无法完成捡拾和输送卵子的功能或包裹卵巢,使其排卵障碍而不能受孕。术后"假性囊肿"或"包裹性积液"易复发。 相似文献
30.
Objective To construct new model of experimental abdominal aortic aneurysm (AAA) and detect the AAA outer diameter and the change of induce nitric oxide synthase(iNOS) in the abdominal aor-tic aneurysm in different period,and analysis the correlation between experimental AAA and iNOS.Methods During the operation of the experiment group,the vascular prosthesis of PTFE was implanted to the rabbit abdominal aorta to form an aneurysm,while sham operation was done in the control group.The tissue of ab-dominal aortic aneurysm was harvested in 1 d,7d,14d,and 28d after operation,respectively.The tissue bo-mogenate concentration of iNOS in the abdominal aortic aneurysm were detected by enzyme linked immu-nosorbent assay (ELISA).Results In experimental group,mean concentration of the tissue bomogenate concentration of iNOS in the abdominal aortic aneurysm in 1 d,7 d,14 d,28 d were (22.129 ±2.518)μ/mL,(27.337±5.321) μ/mL,(36.047±4.584)μ/mL,(44.756±1.799)μ/mL,respectively;In control group,that was (12.499±1.807)μ/mL.The concentration of iNOS in experimental group was significantly higher than that of control group (P < 0.01).The difference during the experimental group all had statisti-cal significance (P < 0.05).Conclusion It is possible that iNOS has some biological function during the formation and progression of the abdominal aortic aneurysm. 相似文献