甲亢患者药物治疗前后TGA,MCA和T淋巴细胞亚群的改变及其意义

甲亢患者药物治疗前后ＴＧＡ、ＭＣＡ和Ｔ淋巴细胞亚群的改变及其意义青岛医学院第二附属医院（２６６０４２）陶小安，于辉，于华，李培本文观察了１００例甲亢患者治疗前后甲状腺球蛋白抗体（ＴＧＡ）、甲状腺微粒体抗体（ＭＣＡ）及Ｔ淋巴细胞亚群的改变，并探讨其临床...     

Graves氏病甲状腺滤泡细胞的扫描电镜观察

用扫描电镜观察了8例治疗后甲状腺机能亢进患者的甲状腺滤泡细胞表面结构。多数滤泡细胞为胞吞功能活跃的Ⅲ型细胞,较少为胞吐功能活跃的Ⅱ型细胞,而功能低下的Ⅰ型细胞更少见或缺如。从甲亢病例的甲状腺滤泡细胞表面结构的观察结果进一步说明甲状腺滤泡细胞表面形态可以反映细胞功能周期变化及不同甲状腺疾病的功能状态。治疗后甲亢患者的甲状腺内可见功能活跃的滤泡细胞转变为功能低下的细胞,从而亦反映了疾病的控制状态。     

介入栓塞治疗甲状腺机能亢进的疗效观察

笔者自１９９７年２月～１０月对１０例甲状腺机能亢进病人应用褐藻微球进行双甲状腺上或下动脉栓塞术，疗效显著，且此种方法具有安全、简单、效果可靠的特点。现将结果报告如下。１临床资料１．１一般资料：应用褐藻微球栓塞甲状腺上或下动脉治疗共１０例。其中女性７例...     

甲状腺功能亢进症病人的家庭康复

甲状腺功能亢进症，内科的一般治疗为避免情绪波动，保适当休息，给高热量富有糖类、蛋白质和B族维生素饮食及服用抗甲状腺药物控制甲亢症状和维持甲状腺功能于正常，在获得明疗效后，将剂量递减，以后巩固治疗，给予的维持量持续应用1～2年，本文就家庭康复治疗中的有前问题加以讨论。1临床资料本组病例12例，男2例，女10例，年龄20～68岁，平均44岁，通过医院治疗控制症状回家服药时间1年以上5例，l～l／年6例，2年以上1例，眼药期间经过随访医护人员及亲属的心理安慰治疗及重视休养环境．建立家庭病历，预防并发症等痊愈门倒，好转1例。…     

Graves病硫脲类药物治疗所致甲减（附32例临床分析）

Ｇｒａｖｅｓ病硫脲类药物治疗所致甲减（附３２例临床分析）广东省广宁县人民医院内科（５２６３００）梁如庆广州军区广州总医院内分泌科王国华，林延德Ｇｒａｖｅｓ病（弥漫性甲状腺肿伴甲状腺功能亢进症）的治疗方面，鉴于多数患者对手术有顾虑，同位素碘治疗尚不能普...     

Functional Maturation of Neuroendocrine Gonadal Axis is Altered by Specific Phase Relations of Circadian Neurotransmitter Activity in Japanese Quail

The preset study was designed to ascertain the effects of temporal relationship of circadian neural oscillations on puberty attainment and reproductive growth of Japances Quail,Coturnix coturnix japonica,Serotonin and dopamine precursors(5-hydroxytryptophan,5-HTP and L-dihydroxyphenylalanine,L-DOPA,5mg/100g body weight)were injected daily,8and 12h apart in two groups of one-day ld chick,while cotrols received two daily injections of normal saline.Weekly/biweekly observations(body weight,cloacal gland size,testicular volume and activity,ovarian follicular diameter and rate of egg production)were made until 9 weeks of age,when the experiment was terminated.Results indicate that 8 h relationship completely suppressed gonadal growth even under long photoperiod(LD16:8),while a 12 h relationship induced precocious sexual maturity and increased the rate of reproductin(spermatogenesis and egg production).It is concluded that circadian phase relationship of serotonergic and dopaminergic activity may not only determine the onset of reproduction in this pultry species,but may also alter the rate of reproduction possibly by affecting photoperiodic mechanism of reproductive regulation.