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101.
Dynamic contrast enhancement of paragangliomas of the head and neck: evaluation with time-resolved 2D MR projection angiography 总被引:5,自引:3,他引:2
Arnold SM Strecker R Scheffler K Spreer J Schipper J Neumann HP Klisch J 《European radiology》2003,13(7):1608-1611
Our objective was to evaluate tumor hemodynamics of paragangliomas of the head and neck. A 2D magnetic resonance projection
angiography (MRPA) protocol was developed. Six patients with histologically proven paragangliomas were included in the study.
The sequence protocol and data post-processing procedure were optimized in view of a high temporal resolution and maximum
contrast-to-noise ratio. Image-time series of two freely orientated slabs could be obtained. Correlation analysis was performed
to generate selective arterial and venous weighted angiographic images. Glomus tumors showed a rapid and intense homogeneous
enhancement following the intravenous administration of contrast material. The smallest tumors investigated measured 10 mm
and could be visualized clearly. Time-resolved analysis of the tumor enhancement revealed an early bolus arrival within the
vascular bed of the tumor and prolonged incomplete washout indicating blood pooling. The dynamic contrast enhancement of glomus
tumors can be evaluated non-invasively with MRPA providing a high temporal resolution and high image quality. The characteristic
contrast enhancement of glomus tumors can be helpful in the diagnostic workup of lesions that may mimic glomus tumors. 相似文献
102.
We investigated strategies involved in odour intensity coding by the primary olfactory centre of insects, the antennal lobe (AL), the structural and functional analogue of the olfactory bulb. Using calcium imaging in the honeybee, we simultaneously measured the projection neuron output responses and a compound signal dominated by receptor neuron input in identified olfactory glomeruli to odours spanning seven log units of concentration. A comparison of the two processing levels indicates that the intercellular computation within the AL modulates and contrast-enhances the primary olfactory signals. As a result the AL network optimizes the olfactory code: odour representation is improved at lower concentrations, the relative activity of olfactory glomeruli allows encoding odour quality over up to four log-unit concentrations, and odour-intensity is reliably represented in the overall excitation across AL. 相似文献
103.
Conzelmann S Malun D Breer H Strotmann J 《The European journal of neuroscience》2001,14(10):1623-1632
Olfactory sensory neurons expressing different members of the mOR37 odourant receptor subfamily send their axons to distinct glomeruli located in the immediate vicinity in the olfactory bulb [Strotmann, J., Conzelmann, S., Beck, A., Feinstein, P., Breer, H. & Mombaerts, P. (2000) J. Neurosci., 20, 6927-6938]. In this study, the potential of transgenic mouse lines was used to explore the onset of receptor expression, the outgrowth of axons as well as the glomerulus formation for two neuron populations expressing different mOR37 subtypes. The data indicate a synchronous time course of these features for both neuron populations. From E15 until the day of birth, the axons of the two mOR37 populations terminate in a common, small area of the presumptive olfactory bulb. During a short postnatal phase, the two axon populations segregate into distinct, protoglomerular structures; some aberrant fibers can still be observed during this period. 相似文献
104.
This paper investigates the generalized ??2 model approximation for differential linear repetitive processes (LRPs). For a given LRP, which is assumed to be stable along the pass, we are aimed at constructing a reduced‐order model of the LRP such that the generalized ??2 gain of the approximation error LRP between the original LRP and the reduced‐order one is less than a prescribed scalar. A sufficient condition to characterize the bound of the generalized ??2 gain of the approximation error LRP is presented in terms of linear matrix inequalities (LMIs). Two different approaches are proposed to solve the considered generalized ??2 model approximation problem. One is the convex linearization approach, which casts the model approximation into a convex optimization problem, while the other is the projection approach, which casts the model approximation into a sequential minimization problem subject to LMI constraints by employing the cone complementary linearization algorithm. A numerical example is provided to demonstrate the proposed theories. Copyright © 2010 John Wiley & Sons, Ltd. 相似文献
105.
The external limiting membrane of the avian embryonic optic tectum is isolated by mechanically separating the neuronal mesencephalon from the overlying mesenchymal tissue. The preparation consists of a basal lamina which is covered on its neural side by endfeet of neuroepithelial cells and has attached to it on its meningeal side a collageneous stroma, containing blood vessels. The external limiting membrane can be flat-mounted on a piece of nitrocellulose filter as mechanical support. It covers an area between 0.3 and 1 cm2, depending on the age of the donor embryo. The endfeet can be removed together with all cellular components of the meninges by treatment with 2% Triton-X-100 or with distilled water. The basal lamina itself is approximately 80 nm thick and consists of two laminae rarae and a central lamina densa. Immunohistochemical staining reveals that the basal lamina in the embryo, after isolation and after detergent extraction of the isolated preparation, contains type IV collagen, nidogen, laminin, and low density heparan sulfate proteoglycan as do other basement membranes. Antibodies against the neural cell adhesion molecule (N-CAM), chondroitin sulfate proteoglycan, and fibronectin fail to stain the external limiting membrane, but these proteins were clearly identified in the blood vessel-containing meninges or in the optic tectum. The flat-mounted external limiting membrane preparation was used as substrate to culture several different neural tissues of central and peripheral origin. Explants of neural crest cells, dorsal root ganglia, and sympathetic ganglia can be cultured on the external limiting membrane. All explants grow well on the basal lamina preparations whether the endfeet are attached or detergent-extracted prior to explantation; however, neurite outgrowth from sympathetic ganglia is reduced in the presence of the endfeet. Although the endfoot-lined external limiting membrane represents at least part of the immediate environment encountered by retinal axons as they invade the optic tectum and despite its excellent properties as a substrate for retinal axons in vitro, cues guiding the orientation of axons were not detected in the flat-mounted preparation. 相似文献
106.
WGA-HRP was applied to the pelvic and pudendal nerves of Sprague-Dawley and Wistar rats to compare the segmental levels of the resulting labeling. L6 and S1 were the segme its at which the sacral parasympathetic nucleus and the denser primary afferents occurred in Sprague-Dawley rats. The levels found in Wistar rats were S1 and S2, Thus indicating a disparity between both strains of rats in the spinal level of the sacral parasympathetic nucleus and the primary afferents. 相似文献
107.
Following horseradish peroxidase (HRP) injections into the preoptic retinopetal nucleus (PRN), neurons in the ipsilateral optic tectum were labeled retrogradely. Labeled neurons exhibited a 'Golgi-like' appearance, somata of these neurons were pyriform or round, and most of them were located in the stratum album centrale (SAC) or the stratum periventriculare (SPV). These neurons had a long apical dendrite, which ramified in the upper-half of SGC into horizontally arborized dendritic fields. The main trunk of the apical dendrites also gave off several branches in the stratum fibrosum et griseum superficiale (SFGS) and reached the stratum opticum (SO). These neurons resemble the 'large pyriform neurons' of Vanegas et al. (Vanegas, H., Laufer, M. and Amat, J., The optic tectum of a perciform teleost. I. General configuration and cytoarchitecture, J. Comp. Neurol., 154 (1974) 43-60) except that in the tecto-PRN neurons the axons originates from the apical dendritic shaft at or near the level of the SAC. Judging from their dendritic patterns, the tectal neurons projecting indirectly to the retina may receive non-retinal inputs besides the retinal input. 相似文献
108.
An HRP study of the central projections from primary sensory neurons innervating the rat masseter muscle 总被引:1,自引:0,他引:1
Retrograde and transganglionic transport of horseradish peroxidase has been used to study the cell bodies of origin and the central projections of neurons innervating the rat masseter muscle. Labeled cell bodies were observed both in the trigeminal ganglion and in the mesencephalic trigeminal nucleus. Major central projections from mesencephalic trigeminal neurons were traced to the supratrigeminal nucleus and to the brainstem reticular formation. Smaller projections from these neurons could be followed to the borders of the solitary tract and hypoglossal nuclei as well as to lamina V of nucleus caudalis and corresponding areas in the dorsal horn at C1−C2 spinal cord segments. Labeling from trigeminal ganglion neurons was observed close to the trigeminal tract in all subdivisions of the trigeminal sensory nuclear complex and in the dorsal horn lamina I at C1 and C2 levels. 相似文献
109.
A. Hofbauer H. Holländer 《Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale》1986,65(1):145-155
Summary Retinal and cortical afferents to the superior colliculus of the rabbit were labelled simultaneously by injecting 3H-leucine into the right eye and HRP into the left visual cortex. It could be shown that there is some convergence of retinal and cortical input onto common postsynaptic elements in the superficial grey, but these cases were found to be rather rare indicating that most afferents from the retina and the visual cortex terminate either on different postsynaptic cells or on different parts of common postsynaptic cells. 相似文献
110.
The projection of the nucleus reticularis tegmenti pontis and adjacent regions of the pontine nuclei to the central cerebellar nuclei in the cat 总被引:1,自引:0,他引:1
The projection of the nucleus reticularis tegmenti pontis (NRTP) and the pontine nuclei (NP) to the central cerebellar nuclei (CCN) was investigated by means of anterograde transport of tritiated leucine. Although termination was found in all the CCN, it was most pronounced in the lateral nucleus and the lateral aspect of the posterior interposed nucleus. The extreme lateral aspect of the anterior interposed nucleus and the caudal part of the fastigial nucleus received a projection of modest intensity. Termination in the infracerebellar nucleus and group Y is likely to be present but could not be confirmed with certainty from the light microscopical material. The contribution from the NP was small and originated from the dorsolateral and dorsal paramedian subdivisions of the NP. Within the NRTP the total area giving rise to projections to the CCN was extensive, and the origin of the projections to the individual CCN overlapped considerably. The projection of the NRTP to the ventrocaudal part of the lateral nucleus was found in conjunction with a projection to the ventrolateral part of the posterior interposed nucleus. Both projections seemed to branch off the fiber bundle terminating in the ventral paraflocculus. Similar correlations could be established in the projection of the NRTP to the dorsal paraflocculus and crus II of the ansiform lobule with other parts of the lateral and posterior interposed nuclei. It was concluded that the transverse, lobular organization of mossy fibers, which differs fundamentally from the longitudinal, modular organization of climbing fibers, is maintained in the collateral projection to the CCN. The results are further discussed in relation to the corticonuclear projection and the engagement of the NRTP and different parts of the CCN in pontocerebellar circuits. 相似文献