全文获取类型
收费全文 | 4971篇 |
免费 | 471篇 |
国内免费 | 38篇 |
专业分类
耳鼻咽喉 | 8篇 |
儿科学 | 483篇 |
妇产科学 | 30篇 |
基础医学 | 503篇 |
口腔科学 | 25篇 |
临床医学 | 195篇 |
内科学 | 155篇 |
皮肤病学 | 116篇 |
神经病学 | 2590篇 |
特种医学 | 26篇 |
外科学 | 144篇 |
综合类 | 336篇 |
预防医学 | 134篇 |
眼科学 | 78篇 |
药学 | 438篇 |
4篇 | |
中国医学 | 192篇 |
肿瘤学 | 23篇 |
出版年
2024年 | 17篇 |
2023年 | 105篇 |
2022年 | 75篇 |
2021年 | 147篇 |
2020年 | 229篇 |
2019年 | 182篇 |
2018年 | 190篇 |
2017年 | 175篇 |
2016年 | 188篇 |
2015年 | 139篇 |
2014年 | 304篇 |
2013年 | 292篇 |
2012年 | 202篇 |
2011年 | 260篇 |
2010年 | 204篇 |
2009年 | 184篇 |
2008年 | 149篇 |
2007年 | 154篇 |
2006年 | 154篇 |
2005年 | 147篇 |
2004年 | 121篇 |
2003年 | 110篇 |
2002年 | 107篇 |
2001年 | 98篇 |
2000年 | 88篇 |
1999年 | 118篇 |
1998年 | 111篇 |
1997年 | 108篇 |
1996年 | 89篇 |
1995年 | 79篇 |
1994年 | 70篇 |
1993年 | 82篇 |
1992年 | 65篇 |
1991年 | 61篇 |
1990年 | 48篇 |
1989年 | 53篇 |
1988年 | 39篇 |
1987年 | 33篇 |
1986年 | 43篇 |
1985年 | 68篇 |
1984年 | 79篇 |
1983年 | 66篇 |
1982年 | 40篇 |
1981年 | 29篇 |
1980年 | 27篇 |
1979年 | 27篇 |
1978年 | 22篇 |
1977年 | 20篇 |
1976年 | 16篇 |
1975年 | 16篇 |
排序方式: 共有5480条查询结果,搜索用时 0 毫秒
11.
本文对28例小儿病毒性心肌炎患者进行了T细胞检测,发现患儿外周血T细胞亚群有明显改变。提示:小儿病毒性心肌炎患者均有不同程度的一过性细胞免疫功能低下。而体液免疫功能正常,我们在临床给与一般治疗的同时,佐以胸腺因子治疗,明显改善症状,取得良好疗效。 相似文献
12.
曾艺东 《白求恩军医学院学报》2005,3(3):137-138
目的观察喜炎平与维生素K3联合治疗小儿秋季腹泻的疗效.方法将89例秋季腹泻患儿随机分为2组.治疗组采用喜炎平与维生素K3联合治疗,对照组则采用利巴韦林治疗,疗程5d.结果治疗组的总有效率为93.3%,显著优于对照组的65.9%(X2=10.37,P<0.01).结论喜炎平与维生素K3联合治疗小儿秋季腹泻值得进一步推广. 相似文献
13.
Although fever may induce seizures, especially in children, its occurrence following epileptic spells has been rarely described, except from generalized convulsive status epilepticus. We present two patients suffering from focal seizures accompanied by episodes of post-ictal fever, and review similar reports in the literature of the last 40 years. Temperature changes following non-convulsive seizures might be induced by gene upregulation occurring in the hypothalamus, the nucleus tractus solitarius, or in other brain regions, producing a local inflammatory response. Direct propagation of electrical discharges seems less consistent with the timing of development of this symptom. Heterogeneity of reported clinical features argues against the assumption of a definite localizing or lateralizing value for post-ictal fever. 相似文献
14.
François Marty 《L'évolution Psychiatrique》2006,71(2):247
The concept of adolescence emerged progressively during the twentieth century. At the onset psychoanalysis focused on puberty as a second stage in the sexual maturity of Man, before it considered adolescence as an active process in the psychic life of the human being. The present article reexamines the development of this concept in the history of ideas in general in order to demonstrate its importance in the history of psychoanalysis. The themes that are sucessively covered include the precursors of the concept in the nineteenth century, the birth of its theorization, the Aichhorn years, and adolescence identified as a psychic process, which participates to a significant degree in subjectivization. 相似文献
15.
T. Hammen F. Kerling M. Schwarz A. Stadlbauer O. Ganslandt B. Keck B. Tomandl A. Dörfler H. Stefan 《European journal of neurology》2006,13(5):482-490
Up to 30% of patients with temporal lobe epilepsy (TLE) remain without remarkable changes in MRI. In this study we investigated the role of (1)H-MR spectroscopy ((1)H-MRS) in lateralizing the affected hemisphere in the mentioned patient group. Twenty-two consecutive patients diagnosed with TLE were investigated by high resolution MRI and (1)H-MRS. We examined the incidence and diagnostic accuracy of temporal metabolite alterations determined by Linear Combination of Model Spectra (L C Model) via water reference. Metabolite values of each hemisphere of TLE patients were compared with healthy controls. Results of metabolite alterations were related to intensive video EEG focus localization. Reduction of N-acetylaspartate + N-acetylaspartyl-glutamate (tNAA) in the affected hemisphere revealed identification in six of nine patients (66%) with unilateral TLE. Group comparison revealed a significant reduction of tNAA (6.1+/-0.8*) in the involved temporal lobe compared with controls (6.67+/-0.4*, P=0.026). Choline levels were significantly increased in the affected hemisphere (1.42+/-0.17*) compared with healthy controls (1.22+/-0.17*, P=0.035). The results of our study show that (1)H-MRS is able to identify the affected hemisphere of MRI negative TLE patients and can be used as an additive tool in multimodal focus localization. 相似文献
16.
Infantile myofibromatosis, congenital fibrosarcoma and congenital/infantile haemangiopericytoma are generally considered distinct entities. Overlapping microscopic features between infantile myofibromatosis and congenital fibrosarcoma, and between infantile myofibromatosis and congenital/infantile haemangiopericytoma, however, have been noted, but not formally reported. This report concerns six neonatal tumours, each exhibiting more than one of the above patterns, supporting a histogenetic relationship among these entities. Immunohistochemistry for smooth muscle actin was found to be useful in the diagnosis of congenital/infantile haemangiopericytoma, and also served to support a histogenetic relationship with the other two entities under consideration. 相似文献
17.
Yoshinori Hamada Masazumi Tsuji Munehisa Kogata Koshiro Hioki Tadashi Matsuda 《Surgery today》1995,25(8):754-756
We report herein a new method of performing laparoscopic pyloromyotomy for infantile hypertrophic pyloric stenosis, using refined surgical techniques. The pyloric tumor was immobilized by grasping the first portion of the duodenum and the anterior wall of the stomach, and electrocoagulation was used prior to incising the pyloric tumor to minimize bleeding during the procedure. Although this technique has been applied in only two patients so far, we present the details herein. We believe that with technical and instrumental refinements, the speed and safety of laparoscopic pyloromyotomy will improve and it will become an alternative to open surgery in pediatric patients. 相似文献
18.
19.
本文对72例全身抽搐发作的患者且24小时脑电图监测期间有临床发作的动态脑电图进行分析,年龄1个月 ̄62岁,其中1个月 ̄14岁67例,结果显示:在临床发作状态下,AEEG均显示痫性放电,且有五种波形。其中42例仅在临床发作时有痫性放电,而发作间歇期背景活动均正常。根据临床及AEEG波形特点,确诊阵挛性发作38例,强直-阵挛性发作13例,复杂性部分发作13例,局限性发作泛化7例,强直发作1例。我们的研 相似文献
20.
Droperidol (DROP) is used in the emergency department (ED) for sedation, analgesia, and its antiemetic effect. Its ED safety profile has not yet been reported in patients (pts). OBJECTIVES: To document the use of DROP in high-risk pts (those with head injury, alcohol or cocaine intoxication, and/or remote or recent seizures), and to determine the number of serious and minor adverse events (AEs)-seizures, hypotension, extrapyramidal side effects (EPSEs)-after DROP. METHODS: The ED database (EmSTAT) was queried to determine who received intramuscular or intravenous DROP in the ED in 1998; further chart review was done if the patient was considered high risk for or had experienced an AE. Multiple regression analysis using a random-effects model determined the significance of each variable in the occurrence of AEs. RESULTS: 2,468 patients (aged 20 months to 98 years; 112 < or =17 years; 141 > or =66 years) received DROP for agitation (n = 1,357), pain (1,135), anxiety (99), vomiting (173), or other reasons (50). There were 945 pts considered high risk; 933 charts were reviewed (DROP mean dose 4.1 +/- 2.0 mg); of these, 50 patient visits did not meet the criteria for high risk. There were 622 pts with head trauma (401 with alcohol use), including 47 with computed tomography (CT) scans positive for brain injury, 64 with cocaine use, and 197 with recent or remote seizures (137 with alcohol use). Minor AEs such as transient hypotension occurred in 96 pts after DROP (73 with alcohol use); 20 received intravenous fluids, while an additional 28 pts (8 with alcohol use) received rescue medications for EPSEs. Six possible serious AEs occurred in pts with serious comorbidities; 2 cases of respiratory depression, 3 post-DROP seizures, and 1 cardiac arrest (resuscitated) 11 hours after DROP in a cocaine-intoxicated pt (normal QT interval). There was no significant difference among high-risk groups in the occurrence of AEs. CONCLUSIONS: The vast majority of pts who received DROP in the ED did not experience an AE. A few serious AEs were noted following DROP in patients with serious comorbidities; it is not clear that DROP was causative. 相似文献