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81.
本文报告了1990年5月以来脑干区大型、复杂占位病变15例.其中,位于脑干内3例,脚间窝2例,岩尖部4例,全岩骨区1例,全斜坡区2例,第四脑室内3例.本组采用以扩大了的岩骨入路为主的联合入路,行肿瘤全切除8例,次全切除5例.2例仅作了活检加减压术.除1例死亡外,均恢复良好.本文结合文献,对脑干区手术入路进行了讨论. 相似文献
82.
Wijeyesinghe E. C. R.; Hawkins T.; keavey Pauline M.; Wilkinson R. 《Nephrology, dialysis, transplantation》1988,3(2):209-213
The value of the Technetium-99m tin colloid (TTC) scan in thediagnosis of renal transplant rejection occurring more than1 month following transplantation was assessed. To our knowledge,use of this agent has not previously been reported. Gamma cameraimaging was performed on 15 occasions in 14 patients in whomplasma creatinine was rising and in three patients in whom renalfunction was stable. Both a qualitative and a quantitative assessmentof images was made. The radioactivity recorded over the graft at 1216 mmpost injection was expressed as a percentage of that recordedat 04 min. In the nine patients in whom graft perfusionwas adequate to allow interpretation of the TTC scan and inwhom rejection was diagnosed by biopsy (six cases) or on clinicalgrounds (three cases), the index ranged from 45 to 153%. Intwo patients the graft was poorly perfused and the accumulationof TTC was predictably low despite the presence of rejection.In the seven patients with either a stable creatinine or withrising creatinine not due to rejection, the index ranged from5 to 43%. Previously reported studies have shown that sulphur colloidsmay be of value in diagnosing graft rejection. This study suggeststhat Tc99m tin colloid may be regarded as a suitable alternativescanning agent and that some simplification of data collectionand analysis can be achieved. 相似文献
83.
The fixation of a distally ruptured ulnar collateral ligament of the MP 1 (Metacarpophalangeal) joint without a portion of ligament which can be sutured or a small bony fragment can be accomplished with a variety of methods, most of which require drillholes through borth cortices and a counter incision as well as the removal of the material at a second stage [1, 11, 13, 15]. The Mitek bone mini anchor (Ethicon-Mitek®) proved to be a reliable and quick alternative [10, 12, 16, 18, 19]. It was successfully used in eleven patients with excellent stability of the reconstructed joint. 相似文献
84.
一种便携式野战多功能骨科手术器械。重量仅1.1kg,体积为215mm×105mm×15mm,如铅笔盒,而功能多达33种,具有结构紧凑、操作简便、一械多用、轻巧便携。价廉实用、效价比高的特点。是基层巡诊、抢险救灾救治中适用的骨科器械。 相似文献
85.
人骨髓间充质干细胞体外分化为雪旺样细胞的方法 总被引:4,自引:0,他引:4
目的 :建立人骨髓间充质干细胞体外向雪旺样细胞定向诱导分化的方法。方法 :取健康人骨髓血标本 ,利用percoll(密度为 1.0 73 g·ml-1)分离骨髓单个核细胞 ,在DMEM LG + 10 % (体积分数 )FBS中培养 ,通过流式细胞术对培养细胞进行表型测定 ,对第 2、3、5、8代间充质干细胞进行定向诱导分化 ,用单抗S 10 0、神经胶质纤维酸性蛋白 (glialfibrillargacidicprotein ,GFAP) ,通过免疫组化方法对诱导的细胞进行鉴定。 结果 :经 percoll分离的间充质干细胞可传 16代 ,细胞数增加了大约 6× 10 7倍。流式细胞术结果显示 :percoll分离出来的未经培养的细胞 ,其CD2 9+CD4 4 +CD3 4 -CD4 5 -细胞数为 3 2 .4 7%± 3 .4 9% ,而培养后贴壁细胞中CD2 9+CD4 4 +CD3 4 -CD4 5 -细胞数为 94 .3 8%± 1.5 0 %。诱导后免疫组化染色结果显示 :由 β ME +bFGF预诱导、β ME +bFGF诱导的S 10 0阳性细胞最多 ,可达 90 %± 4 % ,GFAP阳性细胞为 2 1%± 5 %。结论 :人骨髓中间充质干细胞能定向诱导分化成雪旺样细胞。 相似文献
86.
O. D. Golenko E. E. Batrak M. F. Kharchenko 《Bulletin of experimental biology and medicine》1998,125(3):282-285
Inhibitory effect of glycosaminoglycans isolated from peripheral blood granulocytes of patients with chronic myeloleukemia
and normal subjects on increment in colony-forming units of fibroblasts in monolayer cultures of rat bone marrow is determined
by the degree of sulfation of their main component chondroitin-4-sulfate and by increased content of heparan sulfate.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 125, No. 3, pp. 319–322, March, 1998 相似文献
87.
Felipe A. Calvo David Ortiz de Urbina Luis Sierrasesúmaga Oscar Abuchaibe Ignacio Azinovic Federico Antillon Manuel Santos Jos Canadell 《Pediatric blood & cancer》1991,19(6):478-485
From September 1984 to December 1989, 38 patients of pediatric age with localized bone sarcomas received intraoperative radiotherapy (IORT) as part of a multidisci plinary treatment program. The age ranged from 6 to 21 years. The tumor histologies were 22 osteosarcomas and 16 Ewing's sarcomas. Thirty-four had initial primary disease (90%) and 4 were treated for local recurrence (10%). IORT was used on 32 untreated patients and in 6 previously treated with external beam radiotherapy (EBR). The IORT field included the surgically exposed tumor bed area. Single radiation doses ranging from 10 to 20 Gy were delivered, using 6–20 MeV electron beams. The median follow-up time for the entire group is 25 months (2–65+ months). The projected 5-year disease-free and overall survival rates are 65% and 69%, respectively. One patient developed a local recurrence in each histological group: one chondroblastic osteosarcoma and one cervical Ewing's sarcoma. Six patients died from metastatic progression: 3 initially recurrent tumors and three primary disease cases. Severe neuropathy and soft tissue necrosis were seen in some patients as IORT related complications. IORT is a feasible technique to be integrated in multidisciplinary programs that may promote local control in pediatric and adolescent patients with bone sarcomas. Peripheral nerves are dose-limiting tissue structures for IORT. 相似文献
88.
瘤体骨切除灭活再植治疗四肢长骨巨细胞瘤 总被引:21,自引:0,他引:21
体内刮除及灭活植骨治疗骨巨细胞瘤(GCT)的复发率高。我科从1986年6月~1996年2月治疗四肢长骨GCT24例。随访11个月~8年4个月。其中7例采用局部切刮体内灭活植骨和(或)骨水泥充填治疗。结果1例感染,6例复发,1例恶变后死于肺转移。作者自1991年1月采用瘤体骨切除,离体灭活再植,与骨残端体内灭活相结合,骨缺损采用自家腓、髂骨移植,L-梯形加压钢板(L-TCP)或梯形加压钢板(TCP)固定治疗17例,其中12例保留关节,5例做膝关节融合。本组无菌创口感染1例,1例复发。在保留关节的12例中9例关节功能恢复优良,1例尚可,2例差。充分说明瘤段骨切除体外灭活再植术疗效确实,复发率低。保留关节术式适于关节破坏较轻(<=1/2)者,结合关节残端体内灭活和有效的骨结构重建,有利于恢复关节功能。如关节面累及>1/2,宜做骨关节端切除,灭活再植,下肢宜做关节融合或人工关节置换术。 相似文献
89.
自体骨髓多次注射治疗家兔骨缺损的实验研究 总被引:1,自引:0,他引:1
目的:观察骨髓多次注射的成骨性能。方法:利用家兔实验性骨缺损模型,通过大体、组织学观察,生物力学测定,评价骨髓不同移植次数促进骨缺损愈合的情况。结果:骨髓单次移植能够促进骨缺损的愈合,然而,骨髓二次移植组骨折愈合程度明显优于骨髓单次移植组,但骨髓三次移植组与骨髓二次移植组骨折愈合无明显差异。结论:在骨折愈合早期增加骨髓移植次数,能明显增强骨髓的成骨能力,加快骨折愈合 相似文献
90.
M. Kneissel P. Roschger W. Steiner D. Schamall G. Kalchhauser A. Boyde M. Teschler-Nicola 《Calcified tissue international》1997,61(2):95-100
There is abundant data on cancellous bone in the aging human spine, but little relating to the growing vertebral cancellous
bone in childhood and adolescence. The purpose of this study was to map vertebral cancellous bone in a growth and age series
of historic skeletal samples and to make comparisons with data published on recent material. Lumbar vertebral bodies were
collected from 65 skeletons (0–60 years) from a medieval Nubian population. Ethnohistoric information was collected to interpret
conditions that might have influenced bone structure and metabolism. The cancellous bone was studied three dimensionally,
using stereophotography and scanning electron microscopy and morphometrically by performing a semiautomatic structural analysis
on digitized backscattered electron images of polymethacrylate-embedded material. The cancellous bone structure in the children
consisted mainly of a densely packed, uniform network of small rodlike trabeculae. The greatest bone volume fraction with
small, more platelike trabeculae was observed during adolescence. In young adults, larger platelike trabeculae were present
in the central zone and smaller trabeculae in the superior and inferior zones, as described for modern skeletal material.
Structural changes associated with aging were observed much sooner than in modern man. By the estimated age of approximately
50–60 years, the predominant architectural elements were slender rarified rods in both sexes. The ethnohistorical data suggest
that this was essentially a black African population of physically active peasants, not likely to suffer Vitamin D insufficiency
or deficient calcium intake. Thus an earlier onset of the biological age changes in cancellous bone found in modern populations
was probably prevalent.
Received: 1 March 1996 / Accepted: 31 December 1996 相似文献