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51.
检查30例关节炎患者的关节液,结果示类风湿性关节炎患者关节液中白细胞数为330~72600/mm~3,粒细胞为9~97%,结合关节液的其它物理性质,对类风湿关节炎的诊断有一定参考价值。并观察到类风湿关节炎患者血清中IgG、IgA、IgM和关节液中IgG高于其它类型关节炎。 相似文献
52.
Ulver DERICI Erdal KAN Dilek ERTOY Turgay ARINSOY Ayse DURSUN Zerrin BICIK Sukru SINDEL 《Nephrology (Carlton, Vic.)》2002,7(3):155-157
SUMMARY: Renal involvement is not uncommon in rheumatoid arthritis (RA). Many RA patients have renal dysfunction either secondary to the drugs used to treat arthritis or because of the chronic inflammation. Renal pathologies have often included amyloidosis, drug-related renal disease and mesangial glomerulonephritis. However, membranoproliferative glomerulonephritis has only been rarely reported. We report a case of rheumatoid arthritis associated with membranoproliferative glomerulonephritis that rapidly progressed to end-stage renal disease. 相似文献
53.
54.
带血管蒂岛状筋膜瓣移植治疗晚期类风湿性髋关节炎 总被引:1,自引:0,他引:1
目的:阐明带血管蒂岛状筋膜瓣移植治疗晚期类风湿性髋关节炎的疗效。材料和方法:对42例48髋晚期类风湿性髋关节炎病人采用以旋股外侧血管降支为蒂的股前外侧筋膜瓣移植行患髋成形术。结果:术后随访4~10.5年,平均4.5年,髋关节活动范围术前平均16.5°,术后228.6°,按照Charnley和吴之康人工髋关节置换术后的疗效评定标准,优良29髋、很好13髋、好6髋,尚可、差、很差无。结论:患者年龄在15~40岁之间为合适的治疗年龄。与人工髋关节置换术相比,本方法对髋关节正常结构破坏小;一旦手术失败仍可选用其它治疗方法弥补;且并发症少、费用低、远期效果好。 相似文献
55.
养阴清热、宣痹通络法治疗类风湿性关节炎的临床研究 总被引:5,自引:0,他引:5
目的 观察清络通痹颗粒治疗类风湿性关节炎阴虚络热证的临床疗效。方法 将118例患者随机分为清络通痹颗粒治疗组63例和雷公藤多甙片对照组55例,观察用药前后主要症状、体征和实验室检测指标的变化。结果 治疗组的临床治愈率为9.52%,临床治愈显效率为38.10%,总有效率为90.48%,疗效明显优于对照组的0%、20%、83.64%(P<0.05);治疗组的类风湿因子滴度、血沉、C反应蛋白、免疫球蛋白也明显降低,与对照组相比差异显著(P<0.05或P<0.01)。结论 清络通痹颗粒具有抗炎镇痛、调节免疫紊乱等作用,从而达到控制病情的治疗效果。 相似文献
56.
SOLVEIG WÅLLBERG-JONSSON GÖSTA DAHLÉN OWE JOHNSON GUNILLA OLIVECRONA & SOLBRITT RANTAPÄÄ-DAHLQVIST 《Journal of internal medicine》1996,240(6):373-380
Objective. To evaluate the impact of chronic inflammation on lipoprotein lipase (LPL) levels and triglyceride metabolism in patients with rheumatoid arthritis (RA). Design. Plasma levels of LPL activity and mass before and after heparin were determined in post-menopausal women with active RA and in controls. The results were related to lipid levels and inflammatory variables. The LPL activity and mass together with triglyceride levels were also measured before and 6 h after an oral fat load. Setting. The study was performed on in- and out-patients at a University Rheumatology clinic. The controls came from the same reference area. Subjects. Altogether 17 consecutive post-menopausal female patients with RA and 16 age and sex matched controls were enrolled for the initial determination of LPL. Fifteen of the patients and 15 of the controls agreed to take part in the fat load. Of these, one patient and one control were excluded. Main outcome measures. LPL determination: basal levels and post-heparin levels of LPL activity and mass. Correlations between LPL and blood lipids (cholesterol, triglycerides), lipoprotein levels (high density lipoprotein, HDL; low density lipoprotein, LDL), erythrocyte sedimentation rate (ESR) acute phase proteins (orosomucoid, haptoglobin, fibrinogen mass) and cytokines (tumour necrosis factor α, TNF-α; interleukin 1β, IL-1β; and interleukin-6, IL-6). Fat tolerance test: LPL activity, mass and triglyceride levels before and 6 h after a per oral fat load. Results. Pre-heparin LPL mass (P<0.01) and activity (P<0.01) were significantly lower in the rheumatoid patients. Pre-heparin LPL mass showed no correlation to the lipid levels, but an inverse correlation to several inflammatory parameters; it was significant for orosomucoid (rs=?0.63, P<0.05) and C-reactive protein (CRP) (rs=?0.54, P<0.05) and close to significant for haptoglobin (rs=?0.48, P=0.087) and IL-6 (rs=?0.52, P=0.061). Six hours after a lipid load the LPL activity and mass were significantly lower in RA (P<0.05 and P<0.01, respectively) but the triglyceride level was not significantly different compared to controls. Conclusion. An inverse relationship exists between inflammatory status and pre-heparin LPL mass. Pre-heparin LPL mass reflects mainly the inactive monomeric fraction of LPL. This has been shown to hinder the uptake of remnant lipoprotein particles through competition with lipoprotein bound dimeric LPL for the LDL receptor-related protein (LRP receptor) on hepatocytes and macrophages in culture. A decrease of the level of monomeric LPL in plasma may thus be beneficial for remnant catabolism. The same mechanism may on the other hand increase macrophage uptake of lipids. This may not affect global lipid metabolism but may be important in driving the atherosclerotic process in the vessel wall. 相似文献
57.
58.
Philippe Druet 《Journal of immunological methods》1992,150(1-2):177-184
59.
应用ELISA测定了54例类风湿性关节炎患者、99例非类风湿性关节炎患者以及100例正常人的血清Ⅱ型胶原抗体,结果阳性率分别为90.7%、0、0.54例类风湿性关节炎患者中有7例血清类风湿因子为阴性而Ⅱ型胶原抗体为阳性,且病程均在半年之内。结果表明:Ⅱ型胶原抗体的检测对类风湿性关节炎具有特异性诊断和早期诊断的临床意义。 相似文献
60.
Surgical Principles
Radical arthroscopic synovectomy of rheumatoid shoulder and elbow.
Revised Version from: Operat. Orthop. Traumatol. 4 (1992), 112–129 (German Edition). 相似文献