经腹腔镜先天性肥厚性幽门狭窄手术

目的 探讨小儿先天性肥厚性幽门狭窄腹腔镜微创手术操作要点及经验教训。方法 回顾性分析本组20例患儿全麻下经腹腔镜行幽门环肌切开术。结果 18例一次手术成功，1例术中中转开腹，1例3d后二次手术。全部病例随访2月，预后较好。结论 腹腔镜手术治疗先天性肥厚性幽门狭窄是腔镜技术在新生儿外科领域的成功运用，掌握操作要点，可推广使用。     

卵巢上皮癌组织中MT1-MMP的表达及意义

目的　探讨膜型基质金属蛋白酶 - 1(membranetype - 1matrixmetalloproteinase,MT1-MMP)在卵巢上皮癌组织中的表达及其与肿瘤生物学行为和预后的关系。方法　用免疫组化SP法检测 5 6例卵巢上皮癌组织、 15例卵巢良性肿瘤组织以及 10例正常卵巢组织中MT1-MMP蛋白的表达。结果　 6 7 9%的卵巢上皮癌组织MT1-MMP表达阳性 ,卵巢良性肿瘤组织很少表达 (4/ 15 ) ,正常卵巢组织中几乎不表达 (1/ 10 ) ,差异有显著性 (P <0 0 1)。MT1-MMP的表达水平与临床分期、组织学分级以及淋巴结转移密切相关。在单因素生存分析中 ,MT1-MMP的表达与患者预后不良有关。但是 ,在多因素分析中 ,MT1-MMP的表达并不是一个相对独立的预后因素。结论　①MT1-MMP在卵巢上皮癌中异常高表达 ;②MT1-MMP表达促进卵巢癌的侵袭和转移 ,可作为判断卵巢癌恶性表型的有用指标 ;③MT1-MMP的阳性表达与患者不良预后有关。     

医疗失效模式与效应分析在前列腺良性增生患者留置导尿管流程管理中的应用

[目的]探讨医疗失效模式与效应分析(HFMEA)在前列腺良性增生(BPH)患者留置导尿管流程管理中的应用效果.[方法]选取2019年1?6月(实施HFMEA管理前)本院老年病科收治的33例BPH留置导尿管患者作为对照组,选择2019年7?12月(实施HFMEA管理后)收治的35例BPH留置导尿管患者作为观察组.应用HF...     

胃癌患者免疫功能及炎症水平的变化与腹腔镜术后发生医院感染的关系

目的 探讨胃癌患者免疫功能及炎症水平的变化与腹腔镜手术后发生医院感染的关系.方法 选取腹腔镜手术治疗胃癌并发术后感染患者70例,同期未感染患者70例.检测感染患者血清中免疫细胞及炎症相关因子水平变化情况.结果 感染组患者血清中CD3+、CD4+、CD8+、CD4+/CD8+水平明显低于未感染组(P<0.05);感染组患...     

腹腔镜与开腹手术治疗良性卵巢囊肿的疗效分析

目的:探讨腹腔镜手术治疗卵巢囊肿的临床应用价值。方法:回顾分析2007年1月至2008年1月在我院分别接受腹腔镜与开腹手术治疗卵巢囊肿的患者各32例。结果:腹腔镜组切口明显小于开腹组,术中出血量、手术时间明显少于开腹组,两组比较差异均具有统计学意义(P<0.001);腹腔镜组患者术后镇痛药物使用人数明显少于开腹组(P<0.001),术后肠蠕动恢复时间、住院天数明显短于开腹组(P<0.001),术后工作恢复时间、术后病率明显优于开腹组(P<0.05)。结论:腹腔镜下卵巢囊肿手术安全有效,具有创伤小、术后恢复快、住院时间短及术后病率低等特点。     

Laparoscopic radical hysterectomy using pulsed bipolar system: comparison with conventional bipolar electrosurgery

OBJECTIVE: To compare the efficacy, results and complications of using the pulsed bipolar system (PlasmaKinetic; Gyrus Medical, Maple Grove, MN) and conventional bipolar electrosurgery (Kleppinger bipolar forceps; Richard Wolf Instruments, Vernon Hills, IL) in laparoscopic radical hysterectomy and pelvic lymphadenectomy in the management of early invasive cervical carcinoma. METHODS: This was a retrospective case-control study. We recruited consecutively 38 patients with cervical cancer for laparoscopic radical hysterectomy with pulsed bipolar system. For comparison, we recruited consecutively the latest 38 patients with cervical cancer for laparoscopic radical hysterectomy with conventional bipolar electrosurgery in the same period. From Jan. 2001 to Dec. 2005, total 76 patients with cervical cancer for laparoscopic radical hysterectomy were recruited for statistical analysis. RESULTS: No significant difference was found between the two groups in terms of age, body weight, staging, and hospital stay. There were statistically significant difference in blood loss and operative time. The blood loss was more in conventional bipolar electrosurgery group (mean 564 ml, median 500 ml, range 50-2400 ml) compared with pulsed bipolar system group (mean 397 ml, median 350 ml, range 100-1200 ml) (p<0.03). But there was no statistically significant difference in blood transfusion between the two groups (p=0.454). The operation time for the conventional bipolar electrosurgery group (mean 229 min, median 232 min, range 121-352 min) was longer than that for the pulsed bipolar system group (mean 172 min, median 177 min, range 65-267 min) (p<0.001). None of the laparoscopic procedure was required to be converted to laparotomy. There was no significant difference in the intra-operative complication, but there was statistically less postoperative complication in the pulsed bipolar system group (p<0.01). There was no significant difference in recurrence rate in both groups. CONCLUSIONS: Our findings indicate that pulsed bipolar system is more effective in laparoscopic radical hysterectomy when compared with conventional bipolar electrosurgery. Pulsed bipolar system has advantage over conventional bipolar electrosurgery in less blood loss, shorter operative time, less postoperative complication and may offer an alternative option for patients undergoing laparoscopic radical hysterectomy.     

应用下腹部横纹切口腹腔镜肾切除术的术中护理

目的:探讨应用下腹部皮肤横纹切口在腹腔镜下肾切除术的手术配合经验。方法:配合下腹部皮肤横纹切口腹腔镜下肾切除术患者38例,男23例,女15例。术前进行细致充分的准备,术中熟练配合,密切观察病情。结果:38例手术均顺利完成,切口均为甲级愈合,切口长5～9cm,平均6cm。随访3～22个月,均健在。33例肿瘤患者未发现肿瘤种植转移,亦未见肿瘤复发。结论:对应用下腹部皮肤横纹切口在腹腔镜下肾切除术的患者给予密切配合可确保手术顺利完成,减少并发症的发生。     

常用静脉麻醉药对腹腔镜胆囊切除术后呕吐的影响

目的观察常用静脉全麻药异丙酚、硫喷妥钠及依托咪酯对腹腔镜胆囊切除术后恶心呕吐的影响。方法将330例行腹腔镜胆囊切除术患者随机分为三组,每组110例,分别以异丙酚2mg/kg、硫喷妥钠5mg/kg、依托咪酯0.4mg/kg诱导麻醉,其他药物及麻醉方式均相同。结果术后0～6h内,异丙酚组恶心呕吐的发生率及平均发生次数明显低于硫喷妥钠组及依托咪酯组(P0.05),硫喷妥钠组与依托咪酯组比较差异无统计学意义(P0.05);术后6～48h的时间段内,三组患者恶心呕吐的发生率及发生次数比较差异无统计学意义(P0.05)。结论异丙酚在腹腔镜胆囊切除术后早期抗呕吐作用明显。     

腹腔镜与传统开腹治疗子宫肌瘤的临床效果对比研究

目的探讨腹腔镜手术与传统开腹手术治疗子宫肌瘤的临床效果。方法 71例患者被随机分为实验组（n=36）和对照组（n=35）,实验组组给予腹腔镜子宫肌瘤剔除手术,对照组给予传统开腹手术。结果实验组手术时间显著长于对照组（t=4.386,P〈0.01）,但术中出血量、术后排气时间和住院时间均显著少于对照组（t=4.275,P〈0.01;t=3.369,P〈0.01;t=3.763,P〈0.01）,术后1年复发率差异无统计学意义（x2=2.012,P〉0.05）。结论对于子宫肌瘤我们更倾向于患者行腹腔镜手术,但应根据患者自身具体情况,选择适合自己的手术方式,以有效改善病情。