浅谈医药高等职业教育中的药理学教学

近年来 ,随着教育体制改革的不断深入 ,高等职业教育迎来了新的发展机遇。医药高等职业教育作为其中的重要组成部分 ,主要培养目标是适应医药生产、流通及临床应用的社会服务型人才。药理学作为研究机体与药物之间相互作用规律的一门学科 ,是医学和药学之间的重要桥梁。其内容覆盖面广 ,涉及生理、生化、病理、微生物、免疫及临床医学等知识 ,主要为临床合理用药及药品的研制、生产、经营提供理论指导 ,是医药高职各专业必须掌握的专业知识。然而 ,药理学这门课内容多 ,难点多 ,学生普遍反映较繁杂 ,不易理解、掌握。因此 ,该课程在针对高职…     

Triptolide inhibits T cell activation and proliferation via multiple pathways

Triptolide is potent immunosuppressive has been reported to inhibit autoimmunity, compound isolated from Chinese herbal medicine. Triptolide allograft attributed to the suppression of T cells via NF - kB rejection and GVHD, and its efficacy was previously pathway and apoptosis. In the present study, we detailedly analyzed Triptolide＇ s function on murine primary T cell. We found that Triptolide could inhibit T cell activation and proliferation by dramatically down - regulating cell division and cell cycle. Triptolide inhibited T cell activation in a dose- dependent manner, and the inhibition was mediated by both NF- kB pathway and AP - 1 pathway.     

P17 Pharmacology in the integrated course ＂Basic Medical Sciences＂ in Zhejiang University School of Medicine

According to traditional teaching mode, the courses in preclinical medicine including pharmacology are separately run. This mode causes a series of disadvantages including loose connection between knowledge in different disciplines and weak ability to bridge basic preclinical knowledge and clinical practice. In order to overcome the disadvantages and promote the teaching efficiency, we constructed a new integrated course-Course of Basic Medical Sciences, which includes 6 traditional courses, anatomy, histology and embryology, physiology, pathology, pathophysiology and pharmacology. We integrated these courses based on the human organ systems and according to the principle-＂ From macro to micro, From morphological to functional, From normal to abnormal and From disease to drug therapy＂ and published the series of textbook in 2004. The contents of pharmacology are taught just after pathology and pathophysiology in every organ system. In comparison with the traditional teaching mode, teachers of pharmacology need not spend a lot of time to review preceding knowledge of anatomy and histology, physiology, pathophysiology and pathology. This is helpful in saving time and improving the teaching efficiency.     

清胃散加减结合针灸治疗各型牙痛125例

鸡鸣泻又名晨泻、五更泻，亦有称肾泄者。前二者是以发病时间为名，后者以病理变化命名。此病临床较为常见，一般认为，本病多由阳不足，命门火衰，阴寒内盛所致。因为“肾为胃关”，若肾阳不足，关闭不密，则大便下泻；另一种认识是，子丑五更之后，阳气当渐盛而未复，阴气极盛，则令人洞泄不止。因此，前人治鸡鸣泻用四神丸温肾固涩，后人效法，笔者也更是如此。但在临床实践中，笔者发现应用四神丸，效者固有，不效者亦复不少。原因何在？因为“绵绵晨泻病，不尽命火衰”（南京中医药大学丁光迪教授语），笔者亦深有同感，临证之中探索出…     

对中等职业教育药理实验教学改革的探索

传统的药理实验课仅仅是做为印证、加深课堂理论知识的一种辅助性教学.     

螃蜞菊药理作用及临床观察统计分析

螃蜞菊(又名水花生、喜旱莲子草)为苋科植物空心莲子草(Alteranthera philoxeroides)的根或茎叶。生于田野荒地、池沼、水沟等处,分布北京、江苏、浙江、江西、福建、湖南、湖北等地。全年可采,多鲜用。 [成分]含6甲氧基木犀草素7a—L—鼠李糖甙(7a-L-Rhamnosyl-6-methoxylueolin) [药理]体外试验有抑菌作用(脑膜炎球菌、白     

复方胆宁片的实验研究

复方胆宁片的实验研究湖南省中医药研究院（４１０００６）刘炳午，盛忠宜，唐正平主题词＠复方胆宁片／药理学，实验研究为了探讨复方胆宁片时总胆管、奥狄氏括约肌紧张度的影响以及抑制胆色素类结石、抗炎镇痛等作用的机理，笔者对其进行了实验研究，现将结果报道如下：...