脊柱侧弯矫正术中唤醒心理应激的影响

目的 比较脊柱侧弯矫正术中异氟醚复合瑞芬太尼静吸复合麻醉和异丙酚复合瑞芬太尼靶控静脉麻醉对病人术中唤醒时间、苏醒质量及术后心理应激的影响.方法 60例择期行脊柱侧弯矫正术,美国麻醉医师协会(ASA)的标准分级Ⅰ～Ⅱ级,排除合并高血压、冠心病及精神疾病的病例,年龄18～35岁,随机分为异氟醚复合瑞芬太尼静吸复合组(A组)和异丙酚复合瑞芬太尼靶控静脉麻醉组(B组),每组30例.对A、B两组病人分别于术前1天,术后1天、2天、1周进行跟踪随访调查,用Zung抑郁量表(SDS)、焦虑量表(SAS)来测试评分,作为应激水平的监测(得分大于等于50作为判定焦虑或抑郁症状的标准).结果 A组患者自主呼吸恢复时间、呼之睁眼时间和指令动作恢复时间均短于B组(P<0.05),且唤醒即刻心率、平均动脉压均低于B组,有统计学意义(P＜0.05); SDS、SAS测评结果A组明显低于B组,经统计学处理有显著差异(P＜0.05).结论 异氟醚复合瑞芬太尼静吸复合麻醉用于脊柱侧弯矫正术中可缩短唤醒时间,增加了唤醒试验的可调控性,且唤醒期间血流动力学波动小;唤醒对术后心理应激影响小,具有良好的临床应用价值.     

结核感染T细胞斑点试验在手、腕部腱鞘结核诊断中的应用评价

目的 探讨结核感染T细胞斑点试验(T-cell spot of Tuberculosis,T-SPOT.TB)在手、腕部腱鞘结核诊断中的临床应用价值.方法 通过对2012年1月至2018年1月我院收集64例怀疑手、腕部腱鞘结核临床资料进行回顾性分析,根据病理诊断及临床表现判断有无结核分枝杆菌感染;全部病例均经过T-SP...     

Fatigue Cracking Evolution and Model of Cold Recycled Asphalt Mixtures during Different Curing Times

This paper aims to investigate the fatigue cracking evolution of cold recycled asphalt mixtures with asphalt emulsion (CRME) under different curing times. The fatigue cracking model of CRME based on damage mechanics and fracture mechanics was analyzed according to the fatigue loading curve. Firstly, the fatigue cracking evolution of CRME was studied through an SCB strength test and SCB fatigue test. Then, the fatigue damage mechanics were used to establish a nonlinear fatigue cracking model, and the damage degree of CRME at the initial cracking point was determined. The Paris formula was used to characterize the law of fatigue crack propagation. Finally, the microstructure of CRME was observed by scanning electron microscopy (SEM) with the backscattering method. The results indicate that the initial cracking point appears at around 60% of the fatigue life according to the SCB fatigue test by means of image analysis. The damage variable was obtained through the cracking model, and the value of the damage variable was determined as 0.06–0.17 at the initial cracking point. In addition, the Paris formula showed that the crack growth of CRME can be reflected by the stress intensity factor and correlative parameters. Moreover, cement hydration products were mixed with the asphalt membrane to form a denser spatial structure during the curing process, which may provide higher fatigue performance of CRME. This research may provide a theoretical reference for studying the fatigue cracking behavior of CRME.     

影响出国维和待命士兵应付方式的相关因素

目的 了解参加维和部队士兵在出国前的心理应付方式,探讨应激性心理障碍与应付方式的关系。方法 采用应付方式问卷量表（CSQ）,艾森克（EPQ）个性问卷量表和生活事件量表,Zung焦虑自评量表（SAS）、抑郁自评量表（SDS）,对维和待命士兵进行测评,分组进行对照分析。结果 年龄与“自责”、“幻想”因子呈负相关,文化程度与“求助”因子呈负相关,军龄与“解决问题”呈正相关,与“自责”呈负相关;正性事件分值与“求助”、“合理化”因子呈正相关,负性事件分值与“自责”、“退避”呈正相关,生活事件总值与“自责”、“退避”呈正相关。结论 士兵应付方式与年龄、军龄、文化程度、性格具有相关性,焦虑抑郁组应付方式和对照组有较大差异。在士兵中进行应付方式的教育和训练,有益于平战时的心理健康。     

手法复位结合中药熏洗对踝关节骨折患者等速肌力的影响

目的观察中医手法复位结合中药熏洗对踝关节骨折患者踝关节周围的等速肌力的影响。方法60例踝关节骨折患者随机分为中医组和手术组,各30例。临床愈合后一年半左右进行随访,分析比较两组患者踝关节肌力的等速测试指标。结果手术组患足踝关节肌力的等速测试指标明显低于中医组。结论中医综合治疗有利于踝关节骨折患者踝关节周围肌力的恢复。     

日常胎动记录图预测和评估脐带绕颈胎儿宫内安危的价值研究

背景 胎动(FM)是唯一依赖孕妇自我评估的主观性指标,却可客观反映胎儿宫内安全情况;如何将FM量化并使其成为一个相对客观的评价指标一直是产科医师研究和关注的焦点.目的 通过应用日常胎动记录图(DFMC)预测和评估脐带绕颈胎儿的宫内安危.方法 回顾性选取2010年1月—2016年1月在浙江衢化医院住院分娩的足月孕妇100...     

江苏省医学生酒精滥用相关因素研究

目的 探讨江苏省医学生酒精滥用的危险因素,为制订减少有害使用酒精策略提供参考依据.方法 以江苏省医学生酒精滥用现况调查中319例酒精滥用者作为病例组,按照1:2匹配同性别、专业、年级的对照组638人.采用SPSS 22.0软件进行单因素和多因素条件Logistic回归分析模型分析.结果 江苏省医学生饮酒率为44.59％...     

Evidences for the Involvement of Monoaminergic and GABAergic Systems in Antidepressant-like Activity of Tinospora cordifolia in Mice

The present study was taken up to investigate the effect of petroleum ether extract of Tinospora cordifolia (Wild.) Miers, on depression in mice. The extract (50, 100 and 200 mg/kg, p.o.) was administered for 14 successive days to Swiss young albino mice (either sex) and evaluated for antidepressant-like activity using tail suspension test and forced swim test. Petroleum ether extract at all three doses produced significant antidepressant-like effect in tail suspension test as well as in forced swim test and their efficacies were found to be comparable to imipramine (15 mg/kg, p.o.) and sertraline (20 mg/kg, p.o.). The extract at a dose of 50 mg/kg showed most potent effect and did not show any significant change in locomotor functions of mice as compared to control. The antidepressant-like effect of the extract was significantly reversed by pretreatment of animals with prazosin (a α(1)-adrenoceptor antagonist), sulpiride (a selective dopamine D(2)-receptor antagonist), p-CPA (a serotonin synthesis inhibitor) and baclofen (GABA-B agonist), when tested in tail suspension test. Moreover, petroleum ether extract also reduced the mouse whole brain monoamine oxidase (MAO-A and MAO-B) activities as compared to control, resulting in increase in the levels of brain monoamines. Therefore, the extract may have potential therapeutic value for the management of depressive disorders.     

伊曲康唑与酮康唑比较治疗老年口咽部白色念珠菌感染

目的：评价伊曲康唑对老年口咽部白色念珠菌感染的疗效。方法：患口咽部白色念珠菌感染的老年病人３１例，男性１９例，女性１２例；年龄６６±ｓ８ａ。分治疗组１６例，对照组１５例。前者用伊曲康唑１００ｍｇ，ｐｏ，ｂｉｄ，疗程３ｗｋ；后者用酮康唑２００ｍｇ，ｐｏ，ｂｉｄ，疗程４ｗｋ。结果：伊曲康唑组临床有效率为１００％，酮康唑组为９３％，２组比较无显著性差异（Ｐ＞０．０５）。但伊曲康唑的显效时间、疗程较酮康唑短（Ｐ＜０．０１）。伊曲康唑的不良反应比酮康唑少而轻。结论：伊曲康唑为治疗老年口咽部白色念珠菌感染的有效药物。