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61.
Objects The aims of the study were (1) to review the pathological findings of spinal lipomatous masses associated with congenital spinal dysraphism and (2) to discuss the pathological diagnosis.Methods The pathological records of 47 patients at our institution were reviewed, and three illustrative cases were presented.Conclusion Spinal tumorous lesions associated with spinal dysraphism have been traditionally described as lipoma since they are composed mostly of fatty tissue. However, they are different from lipomas arising in other part of the body in that they often contain various tissues of ecto- and mesodermal origin. In our study, we detected such heterotopic components in 24 out of 47 cases. Although they are also similar to teratoma, it is generally accepted that they are malformative lesions which lack neoplastic potential. We therefore should diagnose them as hamartoma rather than lipoma or teratoma.  相似文献   
62.
Five cases of an unusual pseudoangiomatous variant of spindle cell lipoma are presented. In keeping with more typical cases, these lesions occurred principally in the shoulder and neck regions of adult males. The lesions all had the features of typical spindle cell lipoma but, in addition, exhibited irregular and branching spaces with villiform connective tissue projections, giving a striking angiomatoid appearance. Although the pathogenesis is uncertain, this unusual histological pattern seems to be the result of myxoid degeneration and may lead to a mistaken diagnosis of a true vascular tumour or other non-lipomatous spindle cell lesion.  相似文献   
63.
Although uncommon, many variants of lipomatous lesions in or around salivary glands have been reported in the literature. We report a series of three such cases in the minor salivary gland region. The first case (oral floor) is a well-circumscribed lipocytic lesion admixed with glandular components (mucous acini, serous demilunes and ducts). The second case (alveolar mucosa) is a diffuse lipomatous proliferation with entrapped salivary glandular elements, muscles and blood vessels. The third case (palate) is similar to the first case but the gland is located at the periphery of the lesion. The purpose of the article was to report these three lesions and discuss in relation to other pertaining lipomatous lesions (sialolipoma, lipoadenoma, lipomatosis, lipometaplasia in pleomorphic adenoma and infiltrating lipoma).  相似文献   
64.
BACKGROUNDMost small intestinal lipomas are treated surgically, and some require repeated surgeries for multiple lipomas. However, application of endoscopic submucosal dissection (ESD) technology in the deep small intestine is rarely reported owing to the special anatomical structure of the small intestine, medical equipment limitations, and the lack of relevant experience among endoscopists.CASE SUMMARYTwo patients with small intestinal lipomas treated at the Air Force Medical Center from November 2015 to September 2019 were selected to undergo balloon-assisted ESD to treat the lipomas and explore the technical feasibility and safety of ESD for treating small intestinal lipomas. The two patients successfully underwent balloon-assisted ESD to treat four small intestinal lipomas, with a complete resection rate of 100% (4/4), without intraoperative or postoperative bleeding, perforation, or other complications. After 3-6 mo of postoperative follow-up, the clinical symptoms caused by the lipomas were significantly relieved or disappeared after treatment.CONCLUSIONBalloon-assisted ESD is a safe and reliable new method for treating deep intestinal lipomas and shows good clinical feasibility.  相似文献   
65.
Six spindle cell lipomas and two pleomorphic lipomas were analyzed cytogenetically. One spindle cell lipoma had a supernumerary ring chromosome as the sole anomaly. The other five spindle cell lipomas and both pleomorphic lipomas had hypodiploid stemlines with monosomy 16 or unbalanced aberrations leading to loss of 16q13-qter, a feature distinguishing these lipoma subtypes from other benign and borderline adipose tissue tumor histotypes. Unbalanced aberrations of chromosomes 13 and 10 were found in five and three cases respectively; 13q12 was lost in all of these cases, whereas there was on common deleted segment in chromosome 10. No aberrations involving 12q13–15, which are frequent in typical lipomas, were found. Both pleomorphic lipomas, but none of the spindle cell lipomas, had hypotetraploid sidelines, multiple nonclonal aberrations, and telomeric associations. The present findings reveal a new cytogenetic/histopathological association in adipose tissue tumors.  相似文献   
66.
目的 探讨脊髓髓内脂肪瘤的临床特点及其诱发电位监护下显微神经外科手术治疗方法.方法 对重庆医科大学附属第一医院神经外科2003年3月至2009年1月收治的4例脊髓髓内脂肪瘤患者进行回顾性分析,对其临床表现、诊断方法、治疗与结果作出评价.结果 本组4例患者均在显微镜下行肿瘤分块次全或大部切除术,同时行硬膜减张、椎板切除减压术.术中全程进行诱发电位监护.3例患者出院时症状明显好转,1例出院时症状较术前略有好转.结论 MRI检查是目前诊断脊髓髓内脂肪瘤最有效的影像学手段.为避免术中加重脊髓损伤而出现严重并发症,主张在显微镜下行肿瘤分块次全或大部切除术.术中应用诱发电位监护有助于避免损伤肿瘤周围正常脊髓组织.  相似文献   
67.
A flaccid hemi-face is frequently the most noticeable and cosmetically unacceptable consequence of facial nerve palsy, whether due to trauma, Bell's palsy or other etiologies. A variety of face-lift and reanimation techniques have been utilized in the past, but with time, these frequently require further surgery. We describe the use of Mitek (Norwood, MA) suture anchors for cheek resuspension in a patient with facial palsy. This system is composed of a drill guide, drill, inserter, and anchor. Although the titanium alloy anchors come in multiple sizes, the Mini GII Anchor is typically most appropriate for use in facial procedures. The actual size of the Mini GII Anchor is 1.8 mm in diameter and 5.4 mm in length. Two small arched prongs extend from the body of the anchor, and an eyelet at the superior surface is used for suture placement. When placed into a pre-drilled hole with the insertion tool, the prongs extend, effectively fixing the anchor in place. The drill guide protects adjacent soft tissues during the drilling process and allows drilling to a predetermined fixed depth. Sutures attached to the anchor may then be used for soft tissue fixation to bone.  相似文献   
68.
We report on eleven cases of a distinctive dermal spindle cell lipoma characterized by a mixture of mature adipocytes and spindle-shaped cells in a fibromucinous background. Six lesions showed a moderately well circumscribed plexiform pattern, five a well demarcated nodular pattern with compression of surrounding connective tissue and prominent stromal fibrosis. Clinically, the plexiform type mostly occurred in the thigh-groin-buttock area and the nodular type in the head-neck or acral location. While plexiform lesions were predominantly seen in middle-aged females, nodular types occurred in young adults of either sex. No recurrence was seen in five patients with follow-up. The tumour cells were vimentin positive and a thin cytomplasmic rim of S-100 protein positivity was seen in mature adipocytes. Ultrastructural studies revealed lipoblastic differentiation of spindle-shaped cells with lipid droplets and basal lamina formation. Dermal spindle cell lipomas seem to be the dermal counterpart of the most subcutaneously located spindle cell lipoma.  相似文献   
69.
Lipomatous tumor is least common in the oral cavity. We present a case of atypical lipomatous tumor arising in the lower lip of an 81-year-old male. Clinical diagnosis was mucocele. The tumor measured 12 mm in diameter with a round shape. It was solid, firm, myxomatous and translucent with a small yellowish focus in the central portion. Histologically, the tumor was a circumscribed and well-encapsulated mass with prominent myxoid matrix. The central minor portion showed a well-differentiated liposarcoma. In the myxoid area, lipoblasts and large atypical cells with dense chromatin including floret-like giant cells were seen in abundance. Atypical lipomatous tumor may be indistinguishable from pleomorphic lipoma and its distinction from the latter is based on location as well as relative abundance of floret-type giant cells and lipoblasts. According to its abundance in lipoblasts over floret-like cells, pleomorphic lipoma-like area in our case could also be a part of atypical lipomatous tumor. It may be possible to interpret myxoid change in our case as to represent a superficial counterpart of myxoid malignant fibrous histiocytoma-like change reported in the retroperitoneal lesion.  相似文献   
70.
Four patients with intraosseous lipomas were studied with magnetic resonance imaging. The imaging features and histology of each tumor were compared. Magnetic resonance imaging was very helpful in establishing a pathologic diagnosis. If a severe degree of involution was present, then the magnetic resonance findings could be ambiguous, making diagnosis more difficult.  相似文献   
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