全文获取类型
收费全文 | 188858篇 |
免费 | 12935篇 |
国内免费 | 4696篇 |
专业分类
耳鼻咽喉 | 1549篇 |
儿科学 | 2548篇 |
妇产科学 | 3067篇 |
基础医学 | 25253篇 |
口腔科学 | 3431篇 |
临床医学 | 12575篇 |
内科学 | 23710篇 |
皮肤病学 | 2186篇 |
神经病学 | 15337篇 |
特种医学 | 6778篇 |
外国民族医学 | 1篇 |
外科学 | 14967篇 |
综合类 | 25139篇 |
现状与发展 | 21篇 |
一般理论 | 8篇 |
预防医学 | 15327篇 |
眼科学 | 2355篇 |
药学 | 26085篇 |
54篇 | |
中国医学 | 12731篇 |
肿瘤学 | 13367篇 |
出版年
2024年 | 434篇 |
2023年 | 2480篇 |
2022年 | 5608篇 |
2021年 | 7662篇 |
2020年 | 6309篇 |
2019年 | 6118篇 |
2018年 | 6169篇 |
2017年 | 6885篇 |
2016年 | 6962篇 |
2015年 | 6425篇 |
2014年 | 7272篇 |
2013年 | 11288篇 |
2012年 | 9173篇 |
2011年 | 11117篇 |
2010年 | 7078篇 |
2009年 | 7183篇 |
2008年 | 8813篇 |
2007年 | 9724篇 |
2006年 | 9220篇 |
2005年 | 8485篇 |
2004年 | 7390篇 |
2003年 | 6590篇 |
2002年 | 5238篇 |
2001年 | 4718篇 |
2000年 | 3938篇 |
1999年 | 3341篇 |
1998年 | 2661篇 |
1997年 | 2745篇 |
1996年 | 2505篇 |
1995年 | 2194篇 |
1994年 | 2127篇 |
1993年 | 1784篇 |
1992年 | 1670篇 |
1991年 | 1569篇 |
1990年 | 1368篇 |
1989年 | 1118篇 |
1988年 | 1093篇 |
1987年 | 986篇 |
1986年 | 925篇 |
1985年 | 1361篇 |
1984年 | 1175篇 |
1983年 | 879篇 |
1982年 | 918篇 |
1981年 | 733篇 |
1980年 | 732篇 |
1979年 | 508篇 |
1978年 | 321篇 |
1977年 | 286篇 |
1976年 | 262篇 |
1975年 | 190篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
21.
《The surgeon》2015,13(5):286-291
BackgroundCure of aneurysms which involve the aorta at the level of the visceral arteries and the thoracoabdominal segment remains a considerable surgical enterprise with a relatively high mortality and morbidity despite improvements of the surgical procedure and anesthetic technique. Fenestrated and branched endovascular stent grafts are currently available offering an attractive less invasive option especially for most frail patients. These grafts are relatively recent, technically more demanding to insert than the current stent graft for infrarenal aneurysm and besides, given the relative low frequency of the disease, they are much less used by practitioners. Thus, unconditional widespread of this sophisticated technique may not necessarily benefit patients.MethodsWe reviewed our experiences and articles regarding this concern, 1) who should perform this new technique and 2) in what kind of setting.ConclusionBased on the combined complexities of 1) patients selection, 2) proper planning and manufacturing of the graft, 3) the need for outstanding imaging and operating facilities, 4) and the required endovascular skill of physicians involved in the procedure, we feel that only highly specialized centers should be allowed to perform this complex procedure. 相似文献
22.
目的探讨经皮冠状动脉介入(PCI)和静脉溶栓在急性心肌梗死患者中的应用价值。方法选择我院2013年1月至2014年9月收治的60例急性心肌梗死患者作为研究对象,随机分为实验组和对照组各30例。实验组患者采用PCI治疗,对照组患者采用静脉溶栓治疗,比较两组患者血管再通率、死亡发生率、ST段回落情况、住院时间、近远期不良事件发生率、左室舒张末径和左室射血分数变化情况。结果实验组血管再通率显著高于对照组,差异有统计学意义(P<0.05),而近期和远期不良事件发生率均低于对照组,近期不良事件发生率组间比较差异有统计学意义(P<0.05),而远期不良事件发生率比较差异无统计学意义(P>0.05)。实验组患者死亡发生率、ST段回落和住院时间均低于对照组,差异均有统计学意义(P<0.05)。实验组左室射血分数在术后1个月、3个月和6个月时均显著高于对照组,差异均有统计学意义(P<0.05)。结论急性心肌梗死患者应用PCI治疗可显著提高血管再通率、降低死亡和不良事件发生率,有效改善心功能。 相似文献
23.
24.
《Cancer cell》2020,37(1):123-134.e5
25.
26.
Fluid role boundaries: exploring the contribution of the advanced nurse practitioner to multi‐professional palliative care 下载免费PDF全文
27.
《Clinical neurophysiology》2020,131(1):213-224
ObjectiveSystematically review the abnormalities in event related potential (ERP) recorded in Rett Syndrome (RTT) patients and animals in search of translational biomarkers of deficits related to the particular neurophysiological processes of known genetic origin (MECP2 mutations).MethodsPubmed, ISI Web of Knowledge and BIORXIV were searched for the relevant articles according to PRISMA standards.ResultsERP components are generally delayed across all sensory modalities both in RTT patients and its animal model, while findings on ERPs amplitude strongly depend on stimulus properties and presentation rate. Studies on RTT animal models uncovered the abnormalities in the excitatory and inhibitory transmission as critical mechanisms underlying the ERPs changes, but showed that even similar ERP alterations in auditory and visual domains have a diverse neural basis. A range of novel approaches has been developed in animal studies bringing along the meaningful neurophysiological interpretation of ERP measures in RTT patients.ConclusionsWhile there is a clear evidence for sensory ERPs abnormalities in RTT, to further advance the field there is a need in a large-scale ERP studies with the functionally-relevant experimental paradigms.SignificanceThe review provides insights into domain-specific neural basis of the ERP abnormalities and promotes clinical application of the ERP measures as the non-invasive functional biomarkers of RTT pathophysiology. 相似文献
28.
Wan-Jie Gu 《Journal of thoracic disease》2015,7(11):1885-1886
It is well known that a meta-analysis of randomized controlled trials aims to increase the power and precision of the estimated intervention effects. However, when a meta-analysis includes a limited number of patients and a small number of events, overestimation of intervention effect estimates may occur and could cause spurious results. Although many biases can cause the overestimation, random error may be the most common cause. Trial sequential analysis (TSA) can explore the independent effect of random error on intervention effect estimates in meta-analyses and protect meta-analyses against overestimation due to random error. 相似文献
29.
《Journal of Clinical Orthopaedics and Trauma》2019,10(2):380-386
Additive manufacturing is a rapidly emerging technology which is being successfully implemented in the various field of medicine as well as in orthopaedics, where it has applications in reducing cartilage defects and treatments of bones. The technology helps through systematic collection of information about the shape of the "defects" and precise fabrication of complex 3D constructs such as cartilage, heart valve, trachea, myocardial bone tissue and blood vessels. In this paper, a large number of the relevant research papers on the additive manufacturing and its application in medical specifically orthopaedics are identified through Scopus had been studied using Bibliometric analysis and application analysis is undertaken. The bibliometric analysis shows that there is an increasing trend in the research reports on additive manufacturing applications in the field of orthopaedics. Discussions are on using technological advancement like scanning techniques and various challenges of the orthopaedic being met by additive manufacturing technology. For patient-specific orthopaedic applications, these techniques incorporate clinical practice and use for effective planning. 3D printed models printed by this technology are accepted for orthopaedic surgery such as revision of lumbar discectomy, pelvic surgery and large scapular osteochondroma. The applications of additive manufacturing in orthopaedics will experience a rapid translation in future. An orthopaedic surgeon can convert need/idea into a reality by using computer-aided design (CAD) software, analysis software to facilitate the manufacturing. Thus, AM provides a comprehensive opportunity to manufacture orthopaedic implantable medical devices. 相似文献
30.
OBJECTIVES: To assess the effectiveness and safety of additional bedtime H2‐receptor antagonists (H2RAs) in suppressing nocturnal gastric acid breakthrough (NAB) via a systematic review. METHODS: Eligible trials were identified by searching the Cochrane Central Register of Controlled Trials (CENTRAL) (Cochrane Library Issue 2, 2004), MEDLINE (January 1966–June 2004), EMBASE (January 1980–June 2004) and CINAHL (January 1982–June 2004). Additional hand‐searching was conducted on the proceedings of correlated conferences, eight important Chinese journals and references of all included trials. All randomized controlled trials evaluating H2RAs for the control of NAB were eligible for inclusion. The systematic review was conducted using methods recommended by The Cochrane Collaboration. RESULTS: Only two randomized crossover studies, comprising 32 participants, met the inclusion criteria. Because the design, dosage and duration of the treatments were different between the studies, it was not possible to conduct meta‐analysis. There were no consistent conclusions found between the two included studies in evaluating H2RAs for the control of NAB. CONCLUSIONS: No implications for practice at this stage can be concluded. Appropriately designed large‐scale randomized controlled trials with long‐term follow up are needed to determine the effects of additional bedtime H2RAs in suppressing NAB. 相似文献