基于肠道菌群浅析针灸疗法与多囊卵巢综合征

作为常见的内分泌紊乱性疾病之一,多囊卵巢综合征（polycystic ovary syndrome,PCOS）的患病率呈上升趋势,且逐渐年轻化。针灸疗法作为一种操作简便、不良反应小的特色疗法,可调节肠道菌群,从而有效改善肥胖型PCOS患者的临床症状。本文对肠道菌群与PCOS的关系及针灸疗法基于肠道菌群治疗肥胖型PCOS的机制进行浅析。     

基于文献计量学分析针灸治疗卒中后吞咽障碍的研究动态

[目的] 利用CiteSpace软件对国内针灸治疗卒中后吞咽障碍的相关文献进行可视化分析,揭示该研究领域前沿动态及热点演变,为今后的研究提供建议和参考。[方法] 通过检索中国知网、万方、维普三大中文数据库,检索出从建库至2023年6月针灸治疗卒中后吞咽障碍的相关文献,利用CiteSpace 6.1.R6软件对发文量、作者、机构、     

5-羟色胺及其相关代谢物与运动性中枢疲劳

5-HT作为脑内重要神经递质,参与机体情绪、食欲、睡眠等多项生理功能的调节,又与运动性中枢疲劳发生息息相关.康复理疗是运动疲劳恢复手段之一,对运动性疲劳的消除和运动员竞技状态的提高有良好效果.     

电针配合神经生长因子对脑缺血大鼠学习记忆能力的影响

Objective To observe the effect of nerve growth factor(NGF)and electro-acupuncture(EA) on learning and memory in rats with cerebral ischemia.Methods An experimental model of cerebral ischemiareperfusion was established in 40 rats,who were then randomly divided into a model group,a sham operated group,a NGF group,an acupuncture group and a NGF plus acupuncture group.Three weeks were allowed for the recovery of the blood-brain barrier lesion caused by ischemia-reperfusion before intravenous injection of NGF(10μg/kg,once daily for 15 days)via the vena caudalis.In the two acupuncture groups,this was administered in combination with EA at the Baihui(DU20)and Yamen(DU15)acupoints(frequency 100 Hz,2 mA,20 min/time,once daily for 15 days).Morris' water maze test was used to assess any changes in spatial learning and memory abilities.Results The ischemic rats showed significant learning and memory disorders compared with the sham-operated group.In the NGF group,the rats' learning and memory abilities did not impmve significantly compared with the model group and the EA group.Significantly better learning was observed in the NGF+EA group compared with the model group,the EA group and the NGF group.Conclusion NGF combined with EA can improve the learning and memory abilities of rats with learning and memory dysfunction caused by cerebral ischemia-repedusion.     

颈椎病治疗新思路--颈腰同治

摘要：[目的]探讨针灸“颈腰同治”思路治疗颈椎病的理论依据及临床可行性。[方法]根据颈椎病与腰部疾患的·陆床相关性,从传统经络学说、解剖及脊柱力学平衡的角度,分析颈椎病发病过程中颈部与腰部的相互影响,寻求针灸治疗颈椎病更为有效的治疗方案。[结果]“颈腰同治”治疗颈椎病的理论依据主要在传统经络上,颈椎与腰椎主要靠足太阳经与督脉加强彼此相互联系;生理解剖上,椎体及其周围肌肉、韧带共同维护脊柱的生理平衡;生物力学角度,脊柱力学平衡的改变,可以使颈腰同时受累。[结论]针灸“颈腰同治”治疗颈椎病具有充分的理论基础和较好的临床疗效,为针灸临床治疗颈椎病提供了一种新的治疗思路,值得临床进一步验证与推广。     

小青龙汤对气道高反应性的作用及其神经调节机制的探讨

[目的]探讨小青龙汤对哮喘豚鼠气道高反应性的作用及气道非肾上腺素能非胆碱能神经（NANC）对气道张力的调节机制。[方法]对卵清蛋白诱导的过敏性哮喘动物模型动物给予小青龙汤灌胃治疗。体积描记法测定呼吸功能,肺组织病理切片HE染色观察肺组织形态学,并通过硝酸酶还原法测定血清一氧化氮（NO）含量。[结果]相较正常组,小青龙汤治疗组可降低血清NO含量,并减轻气道狭窄与气道壁炎性细胞的浸润,使肺泡间隔和肺泡腔趋于正常,作用呈浓度依赖性。[结论]小青龙汤可通过降低NANC神经递质NO分泌量,恢复NANC神经对支气管平滑肌的正常调节功能,缓解气道平滑肌痉挛,改善哮喘急性发作时的肺通气功能,降低气道高反应性。     

电针配合神经生长因子对脑缺血大鼠学习记忆能力的影响

Objective To observe the effect of nerve growth factor(NGF)and electro-acupuncture(EA) on learning and memory in rats with cerebral ischemia.Methods An experimental model of cerebral ischemiareperfusion was established in 40 rats,who were then randomly divided into a model group,a sham operated group,a NGF group,an acupuncture group and a NGF plus acupuncture group.Three weeks were allowed for the recovery of the blood-brain barrier lesion caused by ischemia-reperfusion before intravenous injection of NGF(10μg/kg,once daily for 15 days)via the vena caudalis.In the two acupuncture groups,this was administered in combination with EA at the Baihui(DU20)and Yamen(DU15)acupoints(frequency 100 Hz,2 mA,20 min/time,once daily for 15 days).Morris' water maze test was used to assess any changes in spatial learning and memory abilities.Results The ischemic rats showed significant learning and memory disorders compared with the sham-operated group.In the NGF group,the rats' learning and memory abilities did not impmve significantly compared with the model group and the EA group.Significantly better learning was observed in the NGF+EA group compared with the model group,the EA group and the NGF group.Conclusion NGF combined with EA can improve the learning and memory abilities of rats with learning and memory dysfunction caused by cerebral ischemia-repedusion.     

颈源性肩周炎发病与推拿治疗机制研究概况

笔者通过查阅国内外相关文献,总结颈源性肩周炎发病与推拿治疗的相关机制,发现颈椎病引发的颈神经根、窦椎神经和交感神经受刺激,影响肩关节及其周围软组织的正常代谢,产生炎症反应,是颈源性肩周炎的发病机制。而推拿治疗本病的机制有解除肌肉痉挛、改善血液淋巴循环、松解软组织粘连、恢复颈椎力学平衡及镇痛。     

微小RNA在卵巢早衰中的研究概况及应用前景

微小RNA（microRNA,简写为miRNA）是一类真核生物内源性小分子单链RNA（核糖核酸）,长约21~25个核苷酸的非编码RNA,通过结合到mRNA的3’非编码区（3’UTR）,降解mRNA或者抑制其翻译过程,从而抑制转录后基因表达。研究发现miRNA在妇科肿瘤、多囊卵巢综合征、子宫内膜异位症等疾病均有表达且起到了重要作用,最新研究发现miRNA在卵巢早衰发生发展过程中起到了重要作用,本文对miRNA在卵巢早衰研究中的进展及应用前景做如下报道。     

“肺肠同治”法辅助治疗慢性阻塞性肺疾病急性加重期肺热腑实证机械通气患者临床研究

[目的]观察肺肠同治法辅助治疗慢性阻塞性肺疾病急性加重期（acute exacerbation of chronic obstructive pulmonary disease,AECOPD）肺热腑实证机械通气患者的临床疗效。[方法]选取62例浙江中医药大学附属第三医院呼吸与危重症医学科及重症医学科AECOPD并接受有创机械通气的患者,按随机数字表法分为常规治疗组和治疗组,每组31例。常规治疗组予西医治疗,治疗组在西医基础上加用肺肠同治方,观察并比较两组患者中医症候积分、血气指标、呼吸机参数、机械通气时间、并发症和临床疗效。[结果]与本组治疗前比较,常规治疗组血气,呼吸机参数,中医症候（咳喘、咳痰、腹胀便秘、发热、胸闷）积分及总分均改善（P<0.05）;治疗组血气,呼吸机参数,中医症候（咳喘、咳痰、腹胀便秘、发热、胸闷、食欲减退）积分及总分均改善（P<0.05）。组间比较,治疗组血气,呼吸机参数,中医症候（胸闷、咳喘、腹胀便秘、食欲减退）积分及总分,临床疗效较常规治疗组改善明显（P<0.05）;机械通气时间较常规治疗组缩短,并发症减少（P<0.05）。[结论]肺...