Comparison of two closed surgical techniques at isolated pediatric radial neck fractures

IntroductionThis paper aims to compare the clinical and radiological results of children operated using elastic stable intramedullary nailing as described by Métaizeau to those with the closed reduction and percutaneous pinning (CRPP).MethodsResults of 21 pediatric patients with radial neck fracture who were treated by two pediatric surgeons between January 2011 and December 2013 were reviewed retrospectively. 10 were treated with the Métaizeau method versus 11 with the CRPP. Operation time, fluoroscopic exposure time, Mayo elbow performance score (MEPS) and radiological assessment at final follow-up 1 year or greater and complications were main outcome measures.ResultsThe MEPS were excellent in all the patients of both groups. Reduction quality was excellent in 8 patients and good in 2 of the Métaizeau, and excellent in 9 and good in 2 of the CRPP. The fluoroscopy and operating times were statistically significantly greater, 3-fold and 2-fold respectively, in the Métaizeau method compared to the CRPP with comparable functional and radiological results.ConclusionSurgeon should adhere to a closed surgical method of his/her experience for excellent result.Level of evidenceTherapeutic Level III.     

一种新的T波终点定义方法及其在QT间期检测中的应用

T波终点识别是ECG信号QT间期检测中的关键技术。由于T波末端呈对数衰减及易受杂音叠加的影响,使得高精度的T波终点识别显得困难。定义T波末端衰减率至某一阈值δ的时刻为T波终点,并将此法应用于QT间期的自动检测。以T波顶点为标识,将其后的0.2 s数据叠加成一个平均信号φ(t),以函数φ^(t)=Aeαt拟合φ的末端,并利用最小二乘法确定其参数。将此φ函数作为模板去匹配心电图的T波可获得相应的A和α值,并通过微分运算得出T波终点的位置。利用此方法进行QT间期检测,显示出良好的准确性和鲁棒性。     

The association between periodontitis and interleukin-6 genetic polymorphism -174 G/C: A meta-analysis

BackgroundTo evaluate the association between periodontitis and interleukin-6 (IL6) -174 G/C polymorphism by data synthesis and subgroup analysis.MethodsEighteen case-control studies from 16 articles with 1616 cases and 1511 controls were included in this meta-analysis by searching the public databases including PubMed, Embase and Web of Science databases by Jun 2018. Data syntheses were performed using Stata 9.0.ResultsThere were inverse associations of IL6 -174 G/C polymorphism with both general periodontitis and overall periodontitis. In CC vs. GG inheritance model, whose effect was the most profound, the genetic polymorphism reduced the risks of general and overall periodontitis by 60% (95% CI = 0.25-0.65, P < 0.01) and 31% (95% CI = 0.38-0.97, P = 0.04) respectively. In addition, the G/C variation was likely to be protective against moderate (allele C vs. allele G: OR = 0.61, 95% CI = 0.43-0.87, P = 0.01; CC + GC vs. GG: OR = 0.57, 95% CI = 0.37-0.89, P = 0.01) and severe periodontitis (allele C vs. allele G: OR = 0.58, 95% CI = 0.41-0.84, P < 0.01; CC vs. GG: OR = 0.33, 95% CI = 0.13-0.82, P = 0.02) exclusively in Brazilian people. No reliable evidence was found regarding chronic periodontitis.ConclusionThis meta-analysis suggests that IL6 -174 G/C polymorphism may be negatively associated with risk of periodontitis.