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51.
Background and purposePhysical rehabilitation plays an important role in the recovery of motor function after a stroke. This study aimed to evaluate the effects of Tai Chi Yunshou (TCY), a form of physical therapy, on upper-limb function and balance in stroke survivors.MethodsMEDLINE, Embase, CENTRAL and five Chinese databases were retrieved from inception to July 1, 2020 (updated on March 31, 2022). Randomized controlled trials of TCY versus no-treatment for stroke were included. The RoB-2 was used to evaluate the quality of included studies. Upper-limb motor impairment, balance, and activities of daily living (ADLs) were measured by Fugl-Meyer Assessment Upper Extremity Scale (FMA-UE), Berg Balance Scale (BBS), and Barthel Index (BI), respectively. Data synthesis was performed using RevMan (v5.3), and expressed as mean difference (MD) with 95% confidence intervals (CI).ResultsSeven studies with 529 participants were included. Compared with no-treatment, TCY improved FMA-UE (MD = 7.31, 95% CI: 5.86–8.77, minimal clinically important difference [MCID]: 9–10), BBS (MD = 4.68, 95% CI: 0.28–9.07, MCID: 4), and BI (MD = 4.12, 95% CI: 3.28–4.96, MCID: 1.85) in stroke survivors.ConclusionTCY may benefit balance and ADLs in rehabilitation after a stroke, but it may not improve upper-limb function clinically.  相似文献   
52.
药物流产与手术流产对再次妊娠的影响   总被引:4,自引:0,他引:4  
目的 比较药物流产与手术流产对妇女再次妊娠孕期和分娩期的母儿影响 ,为临床选择恰当的人工流产方式提供依据。方法 按知情同意的原则 ,在曾经作过一次药物流产的健康孕妇中 ,随机选择 1 5 0例作为研究组 ;在曾经作过一次手术流产的健康孕妇中选择对照组 1 5 0例 ,研究组与对照组病例资料的基线的差异没有统计学意义 (P>0 .0 5 ) ,具有可比性。观察两组病例的孕期和分娩期母儿的并发症发生情况 ,并随访到分娩后 1周。结果药物流产后再次妊娠的先兆流产发生率、分娩期胎盘异常、早产儿和产后出血发生率比手术流产都低 (P<0 .0 5 ) ,其他结果在两组间的差异没有统计学意义。结论 药物流产对再次妊娠母儿的影响可能小于手术流产 ,故可以作为终止非意愿妊娠的首选 ,尤其是对未育妇女  相似文献   
53.
Background:Intravenous thrombolysis (IVT) is an effective way for treating acute ischemic stroke (AIS). However, its effects have not been established among AIS patients with unclear stroke symptoms or with stroke onset for >4.5 h.Methods:We searched PubMed, Embase, Web of Science, Cochrane Central Register of Controlled Trials and Google Scholar databases for randomized controlled trials that compared IVT (IVT group) and placebo or usual care (control group [CG]) in AIS patients with disease onset for >4.5 h. The outcomes of interest included the favorable functional outcome (defined as modified Rankin Scale [mRS] scores 0–1) at 90 days, the functional independence (defined as mRS scores 0–2) at 90 days, proportion of patients with symptomatic intracerebral hemorrhage (sICH) and death at 90 days. We assessed the risk of bias using the Cochrane tool. Pre-specified subgroup analyses were performed by age (≤70 years or >70 years), National Institute of Health Stroke Scale (NIHSS, ≤10 or >10) and time window (4.5–9.0 h or >9.0 h).Results:Four trials involving 848 patients were eligible. The risk of bias of included trials was low. Patients in the IVT group were more likely to achieve favorable functional outcomes (45.8% vs. 36.7%; OR 1.48, 95% CI 1.12–1.96) and functional independence (63.8% vs. 55.7%; OR 1.43, 95% CI 1.08–1.90) at 90 days, but had higher risk of sICH (3.0% vs. 0.5%; OR 5.28, 95% CI 1.35–20.68) at 90 days than those in the CG. No significant difference in death at 90 days was found between the two groups (7.0% vs. 4.1%; OR 1.80; 95% CI 0.97–3.34).Conclusions:Use of IVT in patients with extended time window may improve their functional outcomes at 90 days, although IVT may induce increased risk of sICH. Care of these patients should well balance the potential benefits and harms of IVT.  相似文献   
54.
Background: Reflex sympathetic dystrophy (RSD) is the common complication among stroke and cerebral injury patients, which is lack of safe and effective treatment. Electroacupuncture (EA) may potentially be a reliably therapy, but the evidence is insufficiency. Methods: Cochrane Library, MEDLINE, Embase, Chinese National Knowledge Infrastructure, Wan Fang Data, the Chinese Biology Medicine disc, etc., were searched, until July 20, 2018. We included random control trials that contrast EA with conventional rehabilitation therapy for the treatment of RSD. Main outcomes were visual analog scale score and Fugl-Meyer upper limb motor function scoring scale, other outcomes such as Barthel index, and hand swelling score were also collected. Data in included studies were extracted into an excel and pooled by Stata/MP 14.1. Results: We incorporated 13 studies involving 1040 RSD patients and outcomes were from 2 to 6 weeks' follow-up. The analgesic effect between 2 groups had statistically significant difference (weighted mean difference [WMD] = ?1.122, 95% confidence interval [CI] [?1.682 to ?.562], P?=?.000], a statistical difference existed in improving dysfunction between 2 groups: (WMD?=?6.039, 95% CI [2.231?.916], P?=?.000). EA groups had a better effect on improving activities of daily life abilities (WMD?=?12.170, 95% CI [6.657?17.682], P < .00011] and better detumescence effect (WMD = ?.800, 95% CI [?1.972 to ?.212], P = .000] contrast to conventional rehabilitation therapy. Conclusions: This meta-analysis supports that EA has a positive effect on alleviating pain, improving limb dysfunction, and promoting activities of daily living. On account of moderate-quality random control trials and high heterogeneity, further high-quality studies are imperative to optimize the EA treatment program.  相似文献   
55.
高风险植入类无源医疗器械的上市后监测是医疗器械风险管理的重要环节,通过对高风险医疗器械上市后安全性信号的监测和评价,最大限度地控制医疗器械潜在的风险,保证医疗器械安全、有效地使用,避免发生群体性严重后果,是医疗器械生产、经营、使用机构和技术监测部门的共同职责.为了更好地促进和辅助高风险植入类无源医疗器械的上市后监测,本...  相似文献   
56.
目的总结国内针刺临床试验数据缺失报告情况,并初步探讨缺失数据经二次分析后对原始结论的影响。方法检索中国知网自2006年1月至2015年12月中文发表的针刺随机对照试验(RCT)文献,筛查后计算缺失数据报告率及数据缺失率,分析数据缺失的原因及意向性分析使用情况;对纳入研究中有缺失数据的两臂分类变量结局指标研究进行意向性分析(ITT),比较分析结果与原文结论的一致性。结果纳入3008篇针刺RCT文献,其中1184篇(39.4%)研究报告了数据缺失情况。2007年数据缺失情况报告率有所下降,但2006—2015年间报告率总体呈上升趋势。3008篇RCT报告中343篇(11.4%)报告了数据缺失原因。对1184篇报告数据缺失情况的研究分析显示,321篇(27.1%)试验报告无缺失数据,余863篇存在数据缺失,数据缺失率≥20%、≥10%且<20%、<10%的报告分别为28篇(2.4%)、209篇(17.6%)、626篇(52.9%)。3008篇纳入报告中仅有63篇(2.1%)提及了ITT分析,且只有30篇(1.0%)报告了ITT分析结果。对358篇报告了分类结局变量的两臂试验数据进行了二次分析,其中108篇(30.2%)研究与原始结论不一致;92篇(85.2%)可能存在假阳性结果,16篇(14.8%)可能存在假阴性结果。结论国内针刺临床研究者对缺失数据的报告及其对研究结果产生的影响的重视程度较低,未采用合理方法处理缺失数据可能会造成假阴性或假阳性的结论。  相似文献   
57.
Knee osteoarthritis (KOA) is a common disorder in elderly. There is no known cure for KOA, and thus therapeutic strategies of alleviating symptoms are increasingly emphasized. Moxibustion has been widely used to treat KOA; however, results are inconclusive. The aim of our study is to critically reassess the effects of moxibustion on KOA.We searched PubMed, EMBASE, Cochrane Central Register of Controlled Trials (CENTRAL), and Chinese Biomedical Literature database (CBM) through 25 November 2015. Two independent reviewers selected studies and abstracted information, as well as assessed the risk of bias using Cochrane risk of bias tool. The random-effects meta-analyses were performed based on abstracted data.We initially captured 163 citations and added 4 records through checking review. After critical appraisal, 13 RCTs were included. Meta-analyses indicated that moxibustion is not statistically different from oral drug in improving the response rate (MD = 1.09; 95% CI = 1.00, 1.20; P = 0.05), alleviating pain and improving physical function. Our meta-analysis also found that moxibustion is superior to usual care and sham moxibustion in reducing WOMAC score (MD = 7.56; 95% CI = 4.11, 11.00; P = 0.00), pain and function, as well as increasing QoL. Moreover, most AEs caused by moxibustion can heal without medical care.We concluded that moxibustion treatment is equal to the oral drugs and intra-articular injections and may be an alternative in treating patients with KOA.  相似文献   
58.
Backgroundand purpose: Although several studies have reported that thread embedding acupuncture (TEA) is effective for lumbar herniated intervertebral disc (LHIVD), the evidence remains limited because previous studies had a high risk of bias. This study aimed to investigate the efficacy and safety of TEA for LHIVD through a rigorously designed trial.Materials and methodsThis was a randomized, patient-assessor-blinded, sham-controlled trial. Participants were screened according to eligibility criteria, and 70 patients with LHIVD were randomly allocated to the TEA and sham TEA (STEA) groups in a 1:1 ratio. Both groups received TEA or STEA treatment at 23 acupoints once per week for eight weeks. Changes in low back pain, radiating pain, Oswestry disability index, Roland–Morris disability questionnaire, EuroQol 5–Dimensions 5–Levels, and global perceived effect were measured at baseline and at 4, 8, 12, and 16 weeks after screening and compared between the two groups.ResultsTEA showed no significant difference in all outcomes compared to STEA immediately after eight weeks of treatment. After an additional eight weeks of follow-up, TEA showed a more significant effect on the low back pain than STEA (p < 0.05) and showed a better tendency in maintaining or enhancing the improvement of radiating pain, function, and quality of life even after the end of treatment. No serious adverse events were observed.ConclusionTEA is effective in improving low back pain in patients with LHIVD and may help improve function and quality of life, especially in the long term.  相似文献   
59.
Background and purposeThe use of dry needling (DN) with other treatments may be more beneficial in managing post-stroke spasticity. We report the effects of DN plus exercise therapy (ET) on wrist flexor spasticity.Patient presentationThe patient was a 45-year-old man with an 8-year history of stroke. The outcome measures included the Modified Modified Ashworth Scale (MMAS), Hmax/Mmax ratio, H-reflex latency, Action Research Arm Test (ARAT), Fugl-Meyer Assessment (FMA), and range of motion (ROM) which were assessed before (T1), after (T2), and after 3-week follow-up (T3).ConclusionThe MMAS was improved at T2 from “3” to “2”. The Hmax/Mmax decreased from 0.77 to 0.53 at T3. The H-reflex latency increased from 15.4 ms to 18.5 ms at T3. The wrist active and passive ROM increased ∼30° and ∼20° at T2, respectively.A 4-session DN plus ET may improve spasticity and ROM. No meaningful improvement was observed in function.  相似文献   
60.
目的 分析运用多准则决策分析法(MCDA)进行中药临床综合评价研究的文献特征和方法学现状,为今后研究者设计和实施中药MCDA研究提供建议.方法 计算机检索PubMed、The Cochrane Library、EMbase、SinoMed及中国知网(CNKI)、维普数据库(CQVIP)、万方数据库,获取自各数据库建库至...  相似文献   
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