数字人体微观研究——量子人体态和力学量的表象

本文主要从量子人体态的表象,量子人体算符的矩阵表示,量子人体公式的矩阵表述,量子人体的么正变换,量子人体的狄喇克符号和量子人体线性谐振子与占有数表象六个方面进行了研究,得到了满意的结果;为数字人体的微观研究提供了理论依据.     

Electrophysiological estimates of the time course of semantic and metrical encoding in Chinese speech production

Previous research has shown that conceptual/semantic information precedes segmental information in stress language production (such as English or Dutch). The present study investigated the relative time course of semantic and metrical encoding during Chinese (a tone language) production. Participants were shown pictures and carried out a dual-choice go/nogo decision based on semantic information (whether the depicted item was of a living or non-living object) and metrical information (whether the tone of picture's name was one type, tone 1 or tone 2, or the other type, tone 3 or tone 4). The behavior data, the N200 (related to response inhibition) and the lateralized readiness potentials (LRP, related to response preparation) indicated that semantic encoding was prior to metrical encoding. It provided evidence for early semantic encoding and later metrical encoding of speech production, and supported the serial model or the cascading model, rather than the parallel model of language production. This conclusion relating to the time course of semantic versus segmental encoding in stress languages might be generalized to semantic versus metrical encoding in tone languages such as Chinese.     

小儿肺热咳喘口服液联合奥司他韦治疗小儿病毒性肺炎的临床研究

目的探讨小儿肺热咳喘口服液联合磷酸奥司他韦颗粒治疗小儿病毒性肺炎的临床疗效。方法选取2017年3月—2018年2月中国人民解放军第306医院收治的病毒性肺炎患儿124例为研究对象,按照随机数字表法分为对照组和治疗组,每组各62例。对照组口服磷酸奥司他韦颗粒,体质量15 kg 30 mg/次,15～23 kg 45 mg/次,23～40 kg 60 mg/次,40 kg 75 mg/次,2次/d。治疗组在对照组治疗的基础上口服小儿肺热咳喘口服液,1～3岁,10m L/次,3次/d;4～7岁,10m L/次,4次/d;8～12岁,20 mL/次,3次/d。两组患儿均连续治疗5 d。观察两组的临床疗效,比较两组的临床改善情况和细胞因子水平。结果治疗后,对照组和治疗组的总有效率分别为80.65%、93.55%,两组比较差异有统计学意义(P0.05)。治疗后,治疗组体温恢复正常时间、咳嗽消失时间、肺啰音消失时间短于对照组,两组比较差异有统计学意义(P0.05)。治疗后,两组C反应蛋白(CRP)、白细胞介素-6(IL-6)、基质金属蛋白酶9(MMP-9)、肿瘤坏死因子α(TNF-α)水平均显著降低,同组治疗前后比较差异有统计学意义(P0.05);且治疗组细胞因子水平明显低于对照组,两组比较差异具有统计学意义(P0.05)结论小儿肺热咳喘口服液联合磷酸奥司他韦颗粒治疗小儿病毒性肺炎具有较好的临床疗效,能改善临床症状,调节细胞因子水平,具有一定的临床推广应用价值。     

舞蹈治疗动作体验对抑郁患者心理状态的影响

  目的  比较真实动作与规定动作体验对抑郁患者心理状态的不同影响并探究其作用机制。  方法  于2021年11—12月协和深圳医院精神科招募26名抑郁患者,按随机区组分别进入实验组与控制组,每组13例。实验组进行真实动作体验,控制组进行规定动作体验。体验前后采用压力感知量表、内感受性知觉多维评估量表、海德堡状态问卷、身体自我效能感量表分别测评。  结果  相较于前测,实验组后测的压力感知显著改善[(2.89±0.97)分vs.(3.84±0.94)分,P < 0.001],幸福感显著提高[(3.51±1.04)分vs.(4.10±0.89)分,P < 0.001],内感受性知觉显著增强[(3.70±0.59)分vs.(4.37±0.63)分,P < 0.001];控制组压力感知显著改善[(3.17±0.72)分vs.(3.59±0.67)分,P=0.003],幸福感显著提高[(3.50±0.82)分vs.(4.04±0.95)分,P=0.006],实验组相较于控制组,压力感知(t=2.394, P=0.023)与内感受性知觉(t=2.400, P=0.025)的改善更显著。内感受性知觉完全中介了动作方式对压力感知的影响(中介效应值为0.243,P < 0.05,占总效应的46%)。  结论  基于舞蹈治疗的动作体验能有效改善抑郁患者的心理状态。内感受性知觉的中介作用可能是真实动作相较于规定动作更有利于抑郁患者减轻压力感知的重要作用机制。      

我科实施护理风险管理的方法与效果

目的降低护理风险，保障孕产妇的住院安全。方法成立护理风险管理小组，按照风险管理程序，实施护理风险鉴别、风险评估、风险控制、风险监督。结果孕产妇对护理的满意度及护理质量提高，护理投诉事件降低。结论对产科病区实施风险管理，可以有效提高护理质量。     

HOLOGIC直接转换DR系统平板探测器分析

本文回顾了放射摄影系统的发展历史,讲述了直接转换DR系统的图像捕获机制,对HOLOGIC直接转换DR系统的Se/TFT探测器的板层结构进行了分析,介绍了几种不同设计方案像素线路的工作原理.     

数字人体微观研究:量子人体的散射理论模型

散射理论模型是量子人体信息机理研究的主要内容.本文主要讨论了量子人体的相互作用表象,量子人体态随时间演化的算符和量子人体的微扰论展开;阐述了量子人体的散射矩阵,量子人体S矩阵的微扰论的展开,量子人体的散射截面和量子人体的分波法;最后,从七个方面对全文进行了结语概括;为量子人体散射机理研究提供理论模型.     

NF-κB调控可卡因行为敏化的BDNF机制简

目的獉獉：探讨脑源性神经营养因子（BDNF）是否作为核因子NF-κB的靶基因,参与NF-κB对可卡因行为敏化的影响。方法獉獉：建立NF-κB抑制剂DDTC作用下的小鼠可卡因诱导行为敏化模型,用Real-time PCR检测海马、前额叶皮质、伏隔核中Bdnf的表达。结果獉獉：可卡因可诱导伏隔核和海马（而非前额叶皮质）中Bdnf的上调,而在DDTC的作用下,总Bdnf及BdnfⅣ在伏隔核、海马和前额叶皮质中分别表达下调、不变和上调。结论獉獉：在不同的脑区NF-κB作用的机制可能不同,在伏隔核中,Bdnf可能作为NF-κB的靶基因参与可卡因行为敏化的形成。     

Protective mechanisms of coenzyme-Q10 may involve up-regulation of testicular P-glycoprotein in doxorubicin-induced toxicity

The anticancer drug; doxorubicin (DOX), causes testicular toxicity as an adverse effect. P-glycoprotein (P-gp) is a multidrug resistance efflux transporter expressed in blood-testis barrier, which extrudes DOX from the testis. We investigated whether DOX-induced gonadal injury could be prevented by the use of antioxidant; coenzyme-Q10 (CoQ10). The involvement of P-gp expression, as a possible protective mechanism, was also investigated. CoQ10 was administered orally for 8 days, and DOX toxicity was induced via a single i.p. dose of 15 mg/kg at day 4. Concomitant administration of CoQ10 with DOX significantly restored testicular oxidative stress parameters and the distorted histopathological picture, reduced the up-regulation of caspase 3 caused by DOX, and increased P-gp expression. We show for the first time that CoQ10 up-regulates P-gp as a novel mechanism for gonadal protection. In conclusion, CoQ10 protects against DOX-induced testicular toxicity in rats via ameliorating oxidative stress, reducing apoptosis and up-regulating testicular P-gp.     

Combined effects of oxytetracycline and Pb on earthworm Eisenia fetida

Combined effects of oxytetracycline (OTC) and Pb on lysosomal membrane stability and coelomocyte apoptosis of earthworm were studied in the paper. Compared with control, the lysosomal membrane stability decreased and coelomocyte apoptosis increased in the treatments of single OTC and Pb contamination. As for compound pollution, combined effect of (5 mg/kg OTC + 50 mg/kg Pb) treatment on earthworm lysosomal was synergistic (except 28 d). However, it was antagonistic at higher concentration of (10 mg/kg OTC + 50 mg/kg Pb) and (20 mg/kg OTC + 50 mg/kg Pb) treatment. In addition, coelomocyte apoptosis of earthworm decreased significantly compared with single OTC, indicating an antagonistic reaction. And joint toxicity of OTC and Pb decreased significantly with the increasing OTC concentration.