全文获取类型
收费全文 | 818篇 |
免费 | 19篇 |
专业分类
耳鼻咽喉 | 6篇 |
儿科学 | 34篇 |
妇产科学 | 25篇 |
基础医学 | 90篇 |
口腔科学 | 7篇 |
临床医学 | 66篇 |
内科学 | 210篇 |
皮肤病学 | 20篇 |
神经病学 | 46篇 |
特种医学 | 52篇 |
外科学 | 136篇 |
综合类 | 2篇 |
预防医学 | 43篇 |
眼科学 | 36篇 |
药学 | 25篇 |
中国医学 | 2篇 |
肿瘤学 | 37篇 |
出版年
2023年 | 51篇 |
2022年 | 63篇 |
2021年 | 46篇 |
2020年 | 89篇 |
2019年 | 24篇 |
2018年 | 26篇 |
2017年 | 31篇 |
2016年 | 42篇 |
2015年 | 53篇 |
2014年 | 66篇 |
2013年 | 25篇 |
2012年 | 29篇 |
2011年 | 17篇 |
2010年 | 30篇 |
2009年 | 26篇 |
2008年 | 13篇 |
2007年 | 15篇 |
2006年 | 13篇 |
2005年 | 15篇 |
2004年 | 7篇 |
2003年 | 15篇 |
2002年 | 12篇 |
2001年 | 6篇 |
2000年 | 10篇 |
1999年 | 17篇 |
1998年 | 10篇 |
1997年 | 12篇 |
1996年 | 16篇 |
1995年 | 5篇 |
1994年 | 11篇 |
1993年 | 2篇 |
1992年 | 4篇 |
1991年 | 4篇 |
1990年 | 9篇 |
1989年 | 3篇 |
1988年 | 4篇 |
1987年 | 5篇 |
1986年 | 2篇 |
1985年 | 3篇 |
1984年 | 1篇 |
1980年 | 1篇 |
1976年 | 1篇 |
1975年 | 1篇 |
1964年 | 1篇 |
1946年 | 1篇 |
排序方式: 共有837条查询结果,搜索用时 31 毫秒
131.
《Hepatology (Baltimore, Md.)》1995,21(4):908-912
Several lines of evidence have suggested that immune mechanisms are involved in the pathogenesis of hepatitis B virus (HBV)- and hepatitis C virus (HCV) -related hepatitis. Study of patients with dual HBV and HCV infection raises the question of which is etiologically more relevant in determining the liver cell damage. To address this issue, proliferation of peripheral blood mononuclear cells (PBMCs) in response to a panel of HBV and HCV antigens was assayed in 13 patients with chronic dual hepatitis B and C, 7 patients with chronic hepatitis B, 7 patients with chronic hepatitis C, and 6 patients with hepatitis B surface antigen (HBsAg) carrier state. Although HBV or HCV hepatitis patients had a significant response to HBV or HCV antigens, respectively, the patients with dual hepatitis B and C exclusively responded to HCV antigens, but not to HBV antigens. One patient who was seropositive for both HBV-DNA and HCV-RNA showed a low response to HBV antigens initially but lost the response 3 months later and became responsive to more HCV antigens. These findings suggest that HCV has a dominant role in the immune response of the patients with dual HBV and HCV infection. 相似文献
132.
133.
134.
135.
136.
137.
138.
Rate and appropriateness of polypharmacy in older patients with hemophilia compared with age‐matched controls
下载免费PDF全文
![点击此处可从《Haemophilia》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Pier Mannuccio Mannucci Alessandro Nobili Emanuela Marchesini Emily Oliovecchio Laura Cortesi Antonio Coppola Elena Santagostino Paolo Radossi Giancarlo Castaman Lelia Valdrè Cristina Santoro Annarita Tagliaferri Cosimo Ettorre Ezio Zanon Giovanni Barillari Isabella Cantori Teresa Maria Caimi Gianluca Sottilotta Flora Peyvandi Alfonso Iorio 《Haemophilia》2018,24(5):726-732
139.
《Digestive and liver disease》2018,50(1):20-26
Background and aimThe aim of this systematic review and meta-analysis was to assess the risk of post-polypectomy bleeding (PPB) in patients that underwent colorectal polypectomy and exposed to ASA/NSAIDs.MethodsRelevant publications were identified in MEDLINE/EMBASE for the period 1950–2016. Studies with specified ASA/NSAIDs exposure and bleeding rate were included. Study quality was ascertained according to Newcastle-Ottawa Scale. Forest plot was based on fixed or random effect models in relation to the heterogeneity.Results11 studies (4 prospective and 7 retrospective) including 9307 patients were included in the analyses. Overall, 344 patients (OR 1.8; 95% CI 1.2–2.7; p-value 0.001, I2 52%) experienced rectal bleeding after procedure. While the rate of immediate PPB on aspirin and/or NSAIDs was not increased (OR 1.1; CI 95% 0.6–2.1; d.f. = 1, p = 0.64, I2 0%), the risk of delayed PPB was augmented (OR 1.7; 95% CI 1.2–2.2; d.f. = 8, p = 0.127, I2 36%).ConclusionsASA/NSAIDs are not a risk factor for immediate PPB but the chance of delayed is increased. 相似文献
140.
《Néphrologie & thérapeutique》2019,15(6):430-438
Positron emission tomography combined with computed tomography (PET/CT) is a nuclear imaging technique which provides anatomical and functional information. PET/CT is increasingly used in non-oncological nephrology since conventional radiological approaches after injection of contrast agents are relatively contra-indicated in patients with chronic kidney disease (CKD). PET/CT after i.v. injection of 18F-fluoro-deoxy-glucose (FDG) is not toxic and is characterized by a high sensitivity. The level of irradiation (∼5 mSv) is acceptable. CKD does not significantly influence tissue uptake of 18F-FDG. The purpose of the present review aims at detailing the non-oncological indications of 18F-FDG PET/CT in general nephrology and after kidney transplantation. Particularly, 18F-FDG PET/CT appears useful in the diagnosis of cyst infection in patients with autosomal dominant polycystic kidney disease, as well as in the characterization of retroperitoneal fibrosis. In kidney transplant recipients, 18F-FDG PET/CT may help in the diagnostic work-up of suspected acute rejection, thereby eventually avoiding unnecessary kidney transplant biopsy. Perspectives in 18F-FDG PET/CT imaging are discussed, including innovative approaches of image analysis. 相似文献